The Immunological Significance of the Thymus

The clonal selection theory of acquired immunity

1959 • 2,008 citations

STUDIES ON ANTIBODY PRODUCTION

1955 • 1,573 citations

IMMUNOLOGICAL FUNCTION OF THE THYMUS

1961 • 1,359 citations

Immunity to Methylcholanthrene-Induced Sarcomas

1957 • 1,241 citations

SYSTEMIC LUPUS ERYTHEMATOSUS

1954 • 1,009 citations

Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.

1960 • 736 citations

Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin.

1953 • 686 citations

The behaviour and fate of skin autografts and skin homografts in rabbits: A report to the War Wounds Committee of the Medical Research Council.

1944 • 661 citations

Myasthenia Gravis: A New Hypothesis

1960 • 585 citations

Effect of Hormones on Lymphatic Tissue

1952 • 512 citations

Quantitative studies on tissue transplantation immunity. II. The origin, strength and duration of actively and adoptively acquired immunity

1954 • 426 citations

Immunofluorescence Demonstration of a Muscle Binding, Complement-Fixing Serum Globulin Fraction in Myasthenia Gravis.

1960 • 396 citations

The clonal selection theory of acquired immunity

1960 • 396 citations

Effect of neonatal thymectomy on the immunological responsiveness of the mouse

1962 • 375 citations

Quantitative studies on tissue transplantation immunity IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease

1959 • 317 citations

Functional alterations in lymphoid tissue induced by adrenal cortical secretion

1945 • 293 citations

Changes in Serum Complement Activity in Patients with Myasthenia Gravis.

1960 • 247 citations

Experimental analysis of the origin of cell types in the development of the mouse thymus

1961 • 224 citations

Skin Homograft Survival in Thymectomized Mice.

1962 • 211 citations

CELLULAR ORIGIN OF RHEUMATOID FACTOR

1959 • 206 citations

IMMUNOLOGIC UNRESPONSIVENESS INDUCED BY PROTEIN ANTIGENS

1955 • 201 citations

Transplantation of Polyoma Virus-induced Tumors in Mice

1961 • 199 citations

CELLULAR SITES OF FORMATION OF GAMMA GLOBULIN

1957 • 197 citations

The significance of antigen in animal tissues.

1949 • 183 citations

EXPERIMENTAL STUDIES ON THE RÔLE OF PLASMA CELLS AS ANTIBODY PRODUCERS

1943 • 178 citations

THE LOCALIZATION OF HOMOLGOUS PLASMA PROTEINS IN THE TISSUES OF YOUNG HUMAN BEINGS AS DEMONSTRATED WITH FLUORESCENT ANTIBODIES

1953 • 171 citations

The Significance of Antigen in Animal Tissues

1949 • 170 citations

The Effect of Splenectomy on the Formation of Circulating Antibody in the Adult Male Albino Rat

1950 • 170 citations

Immunological Recognition of Self

1961 • 166 citations

The Thymic Origin of the Plasma Lymphocytosis Stimulating Factor

1956 • 161 citations

Histological changes in the striped muscles in myasthenia gravis

1953 • 151 citations

Alteration of Homograft Reaction by A-methopterin in Lethally Irradiated Mice Treated with Homologous Marrow

1958 • 143 citations

Lymphocytopoiesis in the bursa of Fabricius

1959 • 142 citations

Quantitative Studies on the Induction of Tolerance of Skin Homografts and on Runt Disease in Neonatal Rats<xref ref-type="fn" rid="fn1">2</xref>

1962 • 140 citations

Precipitin production in chickens. XXI. Antibody production in bursectomized chickens and in chickens injected with 19-nortestosterone on the fifth day of incubasion.

1960 • 138 citations

THE NEW VIEWS AS TO THE MORPHOLOGY OF THE THYMUS GLAND AND THEIR BEARING ON THE PROBLEM OF THE FUNCTION OF THE THYMUS

1921 • 136 citations

IMMUNOLOGICAL DETERMINANTS OF POLYOMA VIRUS ONCOGENESIS

1962 • 130 citations

Detection of Antigenic Differences in Isologous Host-Tumor Systems by Pretreatment with Heavily Irradiated Tumor Cells

1960 • 130 citations

Untersuchungen über Blut und Bindegewebe

1909 • 130 citations

Reactions of Graft against Their Hosts

1959 • 129 citations

A quantitative study of the hemopoietic organs of young albino rats

1940 • 125 citations

The Growth of Cells <italic>in Vivo</italic> in Diffusion Chambers. II. The Role of Cells in the Destruction of Homografts in Mice<xref ref-type="fn" rid="fn1">2</xref>

1955 • 120 citations

The Effect of Thymectomy on the Lymphoid Tissues of the Mouse

1960 • 119 citations

THE AUTOIMMUNE RESPONSE IN MYASTHENIA GRAVIS

1962 • 114 citations

Auto-immune Disease: I. Modern Immunological Concepts

1959 • 113 citations

THE ROLE OF LYMPHOCYTES IN NORMAL AND IMMUNE GLOBULIN PRODUCTION, AND THE MODE OF RELEASE OF GLOBULIN FROM LYMPHOCYTES

1946 • 106 citations

Search for a neuromuscular blocking agent in the blood of patients with myasthenia gravis

1959 • 102 citations

Thymic tumor and acquired agammaglobulinemia: a clinical and experimental study of the immune response.

1956 • 102 citations

A quantitative study of the hemopoietic organs of young adult albino rats

1942 • 97 citations

The Lymphocyte

1958 • 90 citations

Further experimental studies on the role of the plasma cells as antibody producers.

1947 • 90 citations

Immunological aspects of homo- and heterologous bone marrow transplantation in irradiated animals

1957 • 86 citations

Analysis of the Thymus Influence in Leukæmogenesis

1961 • 85 citations

Further Experimental Studies on the Rôle of the Plasma Cells As Antibody Producers

1947 • 84 citations

Acquired Hypogammaglobulinemia in an Adult

1956 • 83 citations

Precipitin Production in Chickens

1960 • 83 citations

Effect of Thymectomy on ‘Delayed’ Hypersensitive Reactions

1962 • 80 citations

Pathological changes in F1 hybrid mice following transplantation of spleen cells from donors of the parental strains.

1959 • 77 citations

THE THYMIC LYMPHOCYTOSIS‐STIMULATING FACTOR

1958 • 75 citations

MODIFICATION OF THE IMMUNE RESPONSE BY RADIATION AND CORTISONE

1957 • 75 citations

THE INFLUENCE OF THYMECTOMY ON ANTIBODY FORMATION

1961 • 73 citations

The rate of mitotic activity in the lymphoid organs of the rat

1949 • 71 citations

Effect of the graft-versus-host reaction on the immunological responsiveness of the mouse

1961 • 70 citations

Studies on the Lymphocyte Production. Investigations on the Nucleic Acid Turnover in the Lymphoid Organs

1945 • 69 citations

TRANSMISSION BY SPLENIC CELLS OF AN AUTOIMMUNE DISEASE OCCURING SPONTANEOUSLY IN MICE

1961 • 68 citations

Antibody Production in the Opossum Embryo

1962 • 68 citations

A Study of the Role of the Thymus and Spleen in the Formation of Antibodies in the Rabbit

1948 • 67 citations

Quantitative studies on the ability of cells of different origins to induce tolerance of skin homografts and cause runt disease in neonatal mice

1961 • 66 citations

Prolongation Of Life With Prevention Of Leukemia By Thymectomy In Mice

1946 • 65 citations

Etiology and Pathogenesis of Mouse Leukemia

1962 • 64 citations

STUDIES ON THE REACTION OF INJECTED HOMOLOGOUS LYMPHOID TISSUE CELLS AGAINST THE HOST

1958 • 64 citations

Comparison of Antibody Responses Associated with the Transfer of Rabbit Lymph-Node, Peritoneal Exudate, and Thymus Cells

1957 • 63 citations

Immunological Tolerance

1961 • 63 citations

Thymus Specificity in Lethally Irradiated Mice Treated with Rat Bone Marrow

1957 • 59 citations

STRAIN VARIATION IN MORTALITY AND RUNT DISEASE IN MICE THYMECTOMIZED AT BIRTH

1962 • 59 citations

Thymic Tumour and Erythroblastic Aplasia Report of Three Cases and a Review of the Syndrome

1960 • 55 citations

Refractory Anemia, Agammaglobulinemia, and Mediastinal Tumor

1957 • 54 citations

Fate of Homologous Adult Spleen Cells injected into New-born Mice

1960 • 52 citations

Über die Natur der Thymus-Elemente

1906 • 50 citations

Antibody Production by Thymus and Peyer's Patches Intraocular Transplants

1955 • 50 citations

Studien über die Thymusinvolution. Die akzidentelle Involution bei Hunger

1908 • 48 citations

Origin and Fate of Cells in the Medulla of Rat Thymus.

1958 • 48 citations

Quantitative Cytological Studies on Thymic Lymphoid Cells in Normal, Preleukaemic and Leukaemic Mice

1961 • 47 citations

Problems in the Surgical Management of Thymic Tumors*

1957 • 44 citations

Thymoma Associated with Myocarditis and the L.E.-Cell Phenomenon

1961 • 44 citations

STUDIES ON THE TRANSFER OF LYMPH NODE CELLS

1954 • 41 citations

Cellular Dose and Age of Host in the Induction of Tolerance

1961 • 41 citations

Delayed Deaths in Sublethally X-rayed F ₁ Hybrid Mice Injected with Parental Strain Spleen Cells

1958 • 39 citations

A Lymphocytosis Stimulating Factor in the Plasma of Chronic Lymphatic Leukaemic Patients

1956 • 38 citations

Susceptibility to Lymphoma Induction by Gross' Passage A Virus in C3Hf/Bi Mice of Different Ages: Relation to Thymic Cell Multiplication and Differentiation<xref ref-type="fn" rid="fn1">2</xref>

1962 • 35 citations

THE DIFFERENTIATION OF CELLS AS A CRITERION FOR CELL IDENTIFICATION, CONSIDERED IN RELATION TO THE SMALL CORTICAL CELLS OF THE THYMUS

1916 • 35 citations

THE BEHAVIOUR OF THYMUS GRAFTS IN HIGH AND LOW LEUKAEMIA STRAINS OF MICE

1961 • 32 citations

Myasthenia gravis followed by systemic lupus erythematosus

1961 • 32 citations

Runt Disease--I

1962 • 29 citations

Thymic involution and regeneration in the albino rat, following injection of acid colloidal substances

1949 • 29 citations

Studies on Mouse Leukaemia. The Fate of Thymus Homografts in Immunologically Tolerant Mice

1960 • 29 citations

PATHOLOGY OF THE THYMUS AND OTHER ORGANS IN MYASTHENIA GRAVIS

1951 • 28 citations

Congestive heart failure in postmenopausal muscular dystrophy: Myositis, myocarditis, thymoma

1957 • 27 citations

STUDIES ON THE HISTOGENESIS OF AUTOPLASTIC THYMUS TRANSPLANTATIONS

1926 • 27 citations

Periodic Acid–Schiff Positive Giant Cells in the Mouse Thymus Cortex

1961 • 26 citations

Thymoma and Hemopoietic Insufficiency

1959 • 23 citations

Precipitin production in chickens. V. The effect of splenectomy on antibody formation.

1950 • 22 citations

TATTOOING OF CAPILLARY HEMANGIOMA

1962 • 22 citations

Further Studies on the Plasma Lymphocytosis Stimulating Factor in Chronic Lymphatic Leukaemia and some other Disease States

1956 • 22 citations

THE HISTOLOGIC PICTURE IN THYROXIN‐INDUCED LYMPHATIC HYPERPLASIA

1959 • 19 citations

Thoracic Duct Lymph and Lymphocytes in the Guinea Pig

1956 • 19 citations

Fate of Antibody Following in vivo Combination with Specific Antigen.

1953 • 19 citations

THE EFFECT OF COLCHICINE ON CIRCULATING ANTIBODIES, ANTIBODY PRODUCING TISSUES AND BLOOD CELLS IN RAT

1953 • 18 citations

CONSEQUENCES OF THYMECTOMY UPON THE LEUCOPOIESIS IN GUINEA PIGS

1957 • 18 citations

Precipitin Production in Chickens

1950 • 13 citations

A chromatographic comparison of the nucleic acids from isologous newborn, adult, and neoplastic thymus.

1961 • 6 citations

THE WEIGHT OF LYMPHOID ORGANS AND THEIR RESPONSE TO ACTH FOLLOWING THYMECTOMY IN THE RAT

1959 • 6 citations

[Effects of a purified thymus extract on the leukopoiesis of thyroidectomized guinea pigs].

1956 • 3 citations