B cell hyperresponsiveness to interleukin 2 and the age-associated decline in murine lupus

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

Separation of mouse spleen cells by passage through columns of sephadex G-10

1974 • 650 citations

A Requirement for Two Cell Types for Antibody Formation in vitro

1967 • 612 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.

1987 • 565 citations

Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.

1986 • 477 citations

Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE).

1983 • 453 citations

Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus.

1982 • 421 citations

Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2.

1981 • 334 citations

Increased Spontaneous Polyclonal Activation of B Lymphocytes in Mice with Spontaneous Autoimmune Disease

1978 • 305 citations

Interleukin 2 deficiency is a common feature of autoimmune mice.

1981 • 198 citations

Demonstration of Activation of B Lymphocytes in New Zealand Black Mice at Birth by an Immunoradiometric Assay for Murine IgM

1977 • 183 citations

Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice.

1980 • 166 citations

Enzyme immunoassay for antibodies to native DNA

1983 • 118 citations

B cell dependence on and response to accessory signals in murine lupus strains.

1983 • 108 citations

Correction of interleukin-2 production in patients with systemic lupus erythematosus by removal of spontaneously activated suppressor cells.

1985 • 92 citations

Significance of Self‐Recognition and Interleukin‐2 for Immunoregulation, Autoimmunity and Cancer

1982 • 87 citations

Production of interleukin 3 and gamma-interferon by an antigen-specific mouse suppressor T cell clone.

1985 • 77 citations

Cellular basis of in vitro anti-DNA antibody production: evidence for T cell dependence of IgG-class anti-DNA antibody synthesis in the (NZB X NZW)F1 hybrid.

1986 • 68 citations

In vitro correction of the interleukin 2 defect of autoimmune mice

1983 • 60 citations

Class-specific regulation of anti-DNA antibody synthesis and the age-associated changes in (NZB x NZW)F1 hybrid mice.

1987 • 55 citations

Cellular processing of pre-proparathyroid hormone involves rapid hydrolysis of the leader sequence.

1979 • 46 citations

Genetic control of lymphocyte suppression. I. Lack of suppression in aged NZB mice is due to a B cell defect.

1978 • 39 citations

Limiting dilution analysis of interleukin 2 and colony-stimulating factor producer cells in normal and autoimmune mice.

1984 • 28 citations

Interleukin‐2 deficiency, genes, and systemic lupus erythematosus

1982 • 28 citations

Interleukin 2 is a proliferative signal for B cells from autoimmune mice

1986 • 24 citations

Is autoimmunity a side-effect of interleukin 2 production?

1986 • 22 citations

Genetic regulation of hypergammaglobulinaemia and the correlation to autoimmune traits in (NZB X NZW) F1 hybrid.

1984 • 18 citations

Suppression of antigen-specific interleukin 2 production in the MRL/MpJ-lpr/lpr Mouse

1986 • 7 citations