Retinoic acid resistance of estradiol-independent breast cancer cells coincides with diminished retinoic acid receptor function

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Statistical methods

1967 • 19,533 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

Textbook of Endocrinology

1952 • 1,475 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation award lecture.

1988 • 703 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

A new retinoic acid receptor identified from a hepatocellular carcinoma

1988 • 613 citations

Familial breast-ovarian cancer locus on chromosome 17q12-q23

1991 • 513 citations

Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer.

1990 • 511 citations

Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site.

1990 • 377 citations

Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

1990 • 330 citations

Mitogenic stimulation of human breast cancer cells in a growth factor‐defined medium: Synergistic action of insulin and estrogen

1988 • 245 citations

Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor

1990 • 211 citations

Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms.

1992 • 200 citations

At least four different chromosomal regions are involved in loss of heterozygosity in human breast carcinoma

1989 • 198 citations

Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.

1991 • 194 citations

Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation.

1991 • 155 citations

lnterleukin-1 Stimulates andAll-Trans-Retinoic Acid Inhibits Collagenase Gene Expression through Its 5′ Activator Protein-1-Binding Site

1990 • 154 citations

Estrogen Stimulates Transcription of c-junProtooncogene

1990 • 150 citations

Expression and regulation of retinoic acid receptors in human breast cancer cells.

1992 • 143 citations

A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell.

1990 • 134 citations

Direct effects of estrogen on c-fos and c-myc protooncogene expression and cellular proliferation in human breast cancer cells

1989 • 122 citations

Presence of Two Members of c-erbA Receptor Gene Family (c-erbAbeta and c-erbA2) in Smallest Region of Somatic Homozygosity on Chromosome 3p21-p25 in Human Breast Carcinoma

1989 • 99 citations

Retinoic acid, a developmental signalling molecule

1990 • 93 citations

‘Nuclear’ oncogenes convert extracellular stimuli into changes in the genetic program

1989 • 83 citations

Phenotypic transformation of normal rat kidney cells in a growth‐factor‐defined medium: Induction by a neuroblastoma‐derived transforming growth factor independently of the EGF receptor

1985 • 81 citations

Retinoid-sensitive cells and cell lines

1990 • 80 citations

Genomic alterations in human breast carcinomas

1990 • 79 citations

Nuclear receptors for retinoids: mediators of retinoid effects on normal and malignant cells

1991 • 68 citations

Role of estrogen-induced insulin-like growth factors in the proliferation of human breast cancer cells.

1990 • 54 citations

The effects of retinoids on proliferative capacities and macromolecular synthesis in human breast cancer MCF-7 cells

1980 • 52 citations

Retinoid modulation of estradiol-stimulated growth and of protein synthesis and secretion in human breast carcinoma cells.

1990 • 52 citations

Effect of retinoic acid and 4-hydroxytamoxifen on human breast cancer cell lines

1984 • 48 citations

Stimulation of TPA-Responsive Element Activity by a Cooperative Action of Insulin and Estrogen in Human Breast Cancer Cells

1990 • 47 citations

Retinoic acid resistance of the variant embryonal carcinoma cell line RAC65 is caused by expression of a truncated RARα

1992 • 43 citations

Regulation of c-myc and c-fos proto-oncogene expression by animal cell growth factors

1988 • 41 citations

Retinoic acid receptors in myeloid leukemia: characterization of receptors in retinoic acid-resistant K-562 cells

1991 • 34 citations

Study of an antiestrogenic effect of retinoic acid in MCF-7 cells

1992 • 29 citations

Modulation of microfilament protein composition by transfected cytoskeletal actin genes.

1988 • 20 citations

Cytoplasmic Retinoic Acid-Binding Protein in Retinoic Acid-Resistant Human Breast Cancer Sublines<xref ref-type="fn" rid="FN1">2</xref>

1984 • 17 citations

Histiocytic lymphoma with sclerosis arising from a nodular lymphoma with a special stromal reaction.An ultrastructural study

1977 • 14 citations

Selective isolation of human breast carcinoma cells resistant to the growth‐inhibitory effects of retinol

1990 • 9 citations

Who goes there?

1988 • 2 citations