A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

1964 • 2,108 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells

1980 • 1,094 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

1989 • 885 citations

Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

1982 • 791 citations

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

1990 • 745 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

A third human retinoic acid receptor, hRAR-gamma.

1989 • 686 citations

A new retinoic acid receptor identified from a hepatocellular carcinoma

1988 • 613 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Retinoic acid and thyroid hormone induce gene expression through a common responsive element

1988 • 586 citations

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain

1989 • 566 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse

1989 • 482 citations

Vitamin A and pattern formation in the regenerating limb

1982 • 463 citations

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

1989 • 437 citations

Thyroid hormone receptor α isoforms generated by alternative splicing differentially activate myosin HC gene transcription

1988 • 425 citations

Isolation of male embryonal carcinoma cells and their chromosome replication patterns

1982 • 422 citations

Differential expression and ligand regulation of the retinoic acid receptor alpha and beta genes.

1989 • 403 citations

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

1989 • 387 citations

Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter

1987 • 361 citations

Retinoic Acid-Induced Neural Differentiation of Embryonal Carcinoma Cells

1983 • 308 citations

Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity

1989 • 308 citations

Nucleotide sequence and evolution of a mammalian α-Tubulin messenger RNA

1981 • 275 citations

Gene Regulation by Steroid Hormones

1990 • 255 citations

Retinoids, homeobox genes, and limb morphogenesis

1989 • 242 citations

Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox.

1988 • 219 citations

Retinoic acid-induced neural differentiation of embryonal carcinoma cells.

1983 • 213 citations

Differentiation and maturation of embryonal carcinoma-derived neurons in cell culture

1988 • 203 citations

Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation

1989 • 192 citations

The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.

1987 • 177 citations

Cyclic AMP analogs and retinoic acid influence the expression of retinoic acid receptor alpha, beta, and gamma mRNAs in F9 teratocarcinoma cells.

1990 • 173 citations

v-erbA specifically suppresses transcription of the avian erythrocyte anion transporter (Band 3) gene

1988 • 153 citations

3. Teratocarcinomas and Embryonic Stem Cells

2016 • 141 citations

Most highly repeated dispersed DNA families in the mouse genome.

1984 • 136 citations

Activation of four homeobox gene clusters in human embryonal carcinoma cells induced to differentiate by retinoic acid

1988 • 135 citations

Metabolism of retinoic acid and retinol during differentiation of F9 embryonal carcinoma cells.

1985 • 127 citations

Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb

1989 • 115 citations

Positional signalling by Hensen’s node when grafted to the chick limb bud

1986 • 110 citations

Polymorphisms in the coding and noncoding regions of murinePgk-1 alleles

1990 • 95 citations

We have a morphogen!

1987 • 85 citations

Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells.

1989 • 79 citations

Isolation and characterization of mouse mutant embryonal carcinoma cells which fail to differentiate in response to retinoic acid.

1981 • 77 citations

Retinoic acid synthesis by cytosol from the alcohol dehydrogenase negative deermouse

1989 • 61 citations

Cell density and cell cycle effects on retinoic acid-induced embryonal carcinoma cell differentiation

1990 • 61 citations

Identification of a translation inhibitory element (TIE) in the 3′ untranslated region of the human interferon-β mRNA

1988 • 59 citations

Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system

1989 • 56 citations

Smooth muscle actin expression during P19 embryonal carcinoma differentiation in cell culture

1990 • 53 citations

Nucleotide sequence and evolution of ETn elements.

1987 • 52 citations

Most Highly Repeated Dispersed DNA Families in the Mouse Genome

1984 • 50 citations

Membrane origin for a signal eliciting a program of cell differentiation

1984 • 44 citations

Metabolism of retinoids by embryonal carcinoma cells.

1985 • 42 citations

Retinoic acid induces a pattern of digits in anterior half wing buds that lack the zone of polarizing activity

1989 • 41 citations

Differential effects of physiological concentrations of retinoic acid in vitro on chondrogenesis and myogenesis in chick craniofacial mesenchyme

1989 • 37 citations

Interruption of two immunoglobulin heavy-chain switch regions in murine plasmacytoma P3.26Bu4 by insertion of retroviruslike element ETn.

1987 • 27 citations

Synthesis and Processing of Small B2 Transcripts in Mouse Embryonal Carcinoma Cells

1990 • 26 citations

Synthesis and processing of small B2 transcripts in mouse embryonal carcinoma cells.

1990 • 21 citations

Polymorphisms in the coding and noncoding regions of murinePgk-1 alleles

1990 • 6 citations

Interruption of Two Immunoglobulin Heavy-Chain Switch Regions in Murine Plasmacytoma P3.26Bu4 by Insertion of Retroviruslike Element ETn

1987 • 5 citations