Regulation of c-myc and c-fos proto-oncogene expression by animal cell growth factors

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

1985 • 753 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

1977 • 695 citations

Functional role for c-myc in mitogenic response to platelet-derived growth factor

1984 • 578 citations

Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos

1987 • 523 citations

Extreme instability of myc mRNA in normal and transformed human cells.

1984 • 522 citations

Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression.

1986 • 516 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Enhanced Transcription of c- myc in Bursal Lymphoma Cells Requires Continuous Protein Synthesis

1985 • 469 citations

Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation.

1986 • 468 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

Levels of c-myc oncogene mRNA are invariant throughout the cell cycle

1985 • 426 citations

Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.

1987 • 381 citations

C-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment

1984 • 362 citations

Microinjected c- myc as a Competence Factor

1985 • 361 citations

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.

1986 • 335 citations

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF

1985 • 331 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors

1985 • 300 citations

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.

1986 • 293 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Participation of c- myc Protein in DNA Synthesis of Human Cells

1986 • 282 citations

Metabolism of c-myc gene products: c-myc mRNA and protein expression in the cell cycle.

1985 • 271 citations

Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells

1985 • 263 citations

Stimulation and inhibition of growth by EGF in different A431 cell clones is accompanied by the rapid induction of c-fos and c-myc proto-oncogenes.

1985 • 257 citations

Regulation of c-myc transcription and mRNA abundance by serum growth factors and cell contact.

1986 • 254 citations

Posttranscriptional mechanisms are responsible for accumulation of truncated c-myc RNAs in murine plasma cell tumors

1985 • 227 citations

Mitogens increase phosphorylation of phosphoinositides in thymocytes

1984 • 223 citations

c-fos expression is neither sufficient nor obligatory for differentiation of monomyelocytes to macrophages

1986 • 204 citations

Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells.

1985 • 203 citations

Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes

1985 • 176 citations

Truncation of exon 1 from the c-myc gene results in prolonged c-myc mRNa stability.

1985 • 172 citations

Identification of a Transcriptional Enhancer Element Upstream from the Proto-Oncogene fos

1985 • 171 citations

Inducible binding of a factor to the c-fos regulatory region.

1987 • 168 citations

Proto-oncogene expression in regenerating liver is simulated in cultures of primary adult rat hepatocytes.

1986 • 167 citations

Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor.

1986 • 159 citations

Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.

1985 • 152 citations

Induction of c-fos and c-myc mRNA by epidermal growth factor or calcium ionophore is cAMP dependent.

1986 • 151 citations

Tumor necrosis factor and interleukin-1 cause a rapid and transient stimulation of c-fos and c-myc mRNA levels in human fibroblasts.

1987 • 150 citations

Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level.

1985 • 149 citations

c-myc regulation during retinoic acid-induced differentiation of F9 cells is posttranscriptional and associated with growth arrest.

1986 • 147 citations

Insulin as a growth factor in rat hepatoma cells. Stimulation of proto-oncogene expression.

1987 • 143 citations

Thyrotropin and dibutyryl cyclic AMP increase levels of c-myc and c-fos mRNAs in cultured rat thyroid cells.

1986 • 140 citations

Multiple Protein-Binding Sites in the 5′-Flanking Region Regulate c-fos Expression

1986 • 133 citations

Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture.

1984 • 132 citations

Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: Similar RNA levels in tumor and proliferating normal cells

1984 • 116 citations

Induction of the c- fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

1986 • 111 citations

Two independent growth factor-generated signals regulate c-fos and c-myc mRNA levels in Swiss 3T3 cells.

1987 • 105 citations

Potentiation of growth factor activity by exogenous c-myc expression.

1986 • 99 citations

The specific induction of myc protooncogene expression in normal human B cells is not a sufficient event for acquisition of competence to proliferate.

1985 • 97 citations

Expression of c-fos in NIH3T3 cells is very low but inducible throughout the cell cycle.

1986 • 97 citations

Interleukin-3-dependent expression of the c-myc and c-fos proto-oncogenes in hemopoietic cell lines.

1986 • 89 citations

Cytoplasmic transfer of the mitogenic response to platelet-derived growth factor.

1981 • 88 citations

Tumorigenicity of fibroblast lines expressing the adenovirus E1a, cellular p53, or normal c-myc genes.

1986 • 85 citations

Transformation of mammalian fibroblasts and macrophages in vitro by a murine retrovirus encoding an avian v-myc oncogene.

1984 • 84 citations

Bombesin induction of c‐fos and c‐myc proto‐oncogenes in Swiss 3T3 cells: Significance for the mitogenic response

1987 • 77 citations

Antisense RNA of Proto-Oncogene c-fos Blocks Renewed Growth of Quiescent 3T3 Cells

1987 • 70 citations

Relatively Stable Population of c-myc RNA that Lacks Long Poly(A)

1987 • 44 citations

A microtubule-activated ATPase from sea urchin eggs, distinct from cytoplasmic dynein and kinesin.

1986 • 37 citations

Murine c-myc retroviruses alter the growth requirements of myeloid cell lines.

1987 • 34 citations

Dissociation of c-fos Induction from Macrophage Differentiation in Human Myeloid Leukemic Cell Lines

1987 • 33 citations

Heparin-treated, v-myc-transformed chicken heart mesenchymal cells assume a normal morphology but are hypersensitive to epidermal growth factor (EGF) and brain fibroblast growth factor (bFGF); cells transformed by the v-Ha-ras oncogene are refractory to EGF and bFGF but are hypersensitive to insulin-like growth factors.

1985 • 31 citations

Differential Responsiveness of myc- and ras-Transfected Cells to Growth Factors: Selective Stimulation of myc-Transfected Cells by Epidermal Growth Factor

1986 • 29 citations

c-myc Regulation during Retinoic Acid-Induced Differentiation of F9 Cells Is Posttranscriptional and Associated with Growth Arrest

1986 • 24 citations

Dissociation of c-fos induction from macrophage differentiation in human myeloid leukemic cell lines.

1987 • 21 citations

Tumorigenicity of Fibroblast Lines Expressing the Adenovirus E1a, Cellular p53, or Normal c-myc Genes

1986 • 19 citations

Relatively stable population of c-myc RNA that lacks long poly(A).

1987 • 18 citations