Immunodeficiency of Aging

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Prevention and Control of Influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP)

2001 • 4,817 citations

The Concept of Immunological Surveillance

2015 • 1,586 citations

Risk Factors for Lung Cancer and for Intervention Effects in CARET, the Beta-Carotene and Retinol Efficacy Trial

1996 • 1,248 citations

Slowing of wound healing by psychological stress

1995 • 1,096 citations

Disclosure of traumas and immune function: Health implications for psychotherapy.

1988 • 1,042 citations

Population-Based Study of Herpes Zoster and Its Sequelae

1982 • 924 citations

-Tocopherol and beta-Carotene Supplements and Lung Cancer Incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: Effects of Base-line Characteristics and Study Compliance

1996 • 884 citations

Chronic stress alters the immune response to influenza virus vaccine in older adults.

1996 • 791 citations

Regulation of the immune response by prostaglandins

1980 • 772 citations

Admission criteria for immunogerontological studies in man: The senieur protocol

1984 • 754 citations

Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.

1993 • 752 citations

The Incidence of Herpes Zoster

1995 • 626 citations

Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults

1995 • 613 citations

Options for the control of influenza III

1997 • 591 citations

Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects

1990 • 581 citations

Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative.

1993 • 577 citations

Vitamin E Supplementation and In Vivo Immune Response in Healthy Elderly Subjects

1997 • 541 citations

RETRACTED: Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjects

1992 • 529 citations

Stress, loneliness, and changes in herpesvirus latency

1985 • 500 citations

Potassium and Calcium Channels in Lymphocytes

1995 • 488 citations

AGEING, IMMUNE RESPONSE, AND MORTALITY

1974 • 480 citations

Interleukin‐6: A Cytokine for Gerontolgists

1993 • 457 citations

Immune Parameters in a Longitudinal Study of a Very Old Population of Swedish People: A Comparison Between Survivors and Nonsurvivors

1995 • 374 citations

Aging and Immune Function

1991 • 361 citations

Age and sex associations of 40 autoimmune diseases

1994 • 355 citations

A Population-Based Serologic Survey of Immunity to Tetanus in the United States

1995 • 350 citations

Tuberculosis as an Endemic and Nosocomial Infection among the Elderly in Nursing Homes

1985 • 345 citations

The Incidence of Giant Cell Arteritis in Olmsted County, Minnesota: Apparent Fluctuations in a Cyclic Pattern

1995 • 338 citations

The Clinical Effectiveness of Pneumococcal Vaccine in the Elderly

1988 • 323 citations

Interleukin-6 and aging: blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction.

1993 • 322 citations

Psychosocial enhancement of immunocompetence in a geriatric population.

1985 • 316 citations

Nutrition and immunology

1988 • 314 citations

[EPIDEMIOLOGY OF CANCER].

1963 • 314 citations

Vitamin E

1995 • 309 citations

Cell-Mediated Immunity as a Predictor of Morbidity and Mortality in Subjects Over 60

1990 • 304 citations

Immune Responses to Varicella-Zoster in the Aged

1982 • 289 citations

Lymphocyte Phytohemagglutinin Responsiveness, Immunoglobulins and Autoantibodies in Aging Humans

1973 • 286 citations

Prevalence of Undiagnosed Pernicious Anemia in the Elderly

1996 • 284 citations

Promotion of wound repair in old mice by local injection of macrophages.

1989 • 247 citations

Dietary Restriction of Adult Male Rhesus Monkeys: Design, Methodology, and Preliminary Findings From the First Year of Study

1993 • 224 citations

AIDS Risk Behaviors Among Late Middle-aged and Elderly Americans

1994 • 220 citations

EXPERIMENTAL INDUCTION OF ATHERO-ARTERIOSCLEROSIS BY THE SYNERGY OF ALLERGIC INJURY TO ARTERIES AND LIPID-RICH DIET

1966 • 202 citations

Giant cell arteritis in Iceland.

1994 • 187 citations

Epidemiology of primary glomerular diseases in a French region. Variations according to period and age

1994 • 179 citations

Importance of age at infection with HIV-1 for survival and development of AIDS in UK haemophilia population

1996 • 178 citations

Immunological responses of healthy elderly population.

1982 • 177 citations

Estimates of the US health impact of influenza.

1993 • 169 citations

Epstein-Barr virus replication within pulmonary epithelial cells in cryptogenic fibrosing alveolitis.

1995 • 164 citations

Effect of social support on stress-related changes in cholesterol level, uric acid level, and immune function in an elderly sample

1985 • 163 citations

Age, Thymic Involution, and Circulating Thymic Hormone Activity*

1978 • 162 citations

Stress, behavior, and immunity: Animal models and mediating mechanisms

1982 • 161 citations

Specific Humoral Immunity in the Elderly: in vivo and in vitro Response to Vaccination

1993 • 159 citations

Age‐related changes in lymphokine production related to a decreased number of CD45RB^hi CD4⁺ T cells

1991 • 154 citations

Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E

1997 • 152 citations

Association of Influenza Immunization With Reduction in Mortality in an Elderly Population

1988 • 150 citations

Immunological studies of Aging. III. Cytokinetic basis for the impaired response of lymphocytes from aged humans to plant lectins.

1977 • 146 citations

The inositol 1,4,5-trisphosphate receptor is essential for T-cell receptor signaling.

1995 • 143 citations

Stress and the memory T-cell response to the Epstein-Barr virus in healthy medical students.

1993 • 140 citations

Sensitivity of lymphocytes to prostaglandin E2 increases in subjects over age 70.

1979 • 139 citations

Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae.

1993 • 139 citations

Cytokine production pathway in the elderly

1996 • 138 citations

The Significance of the Tuberculin Skin Test in Elderly Persons

1987 • 136 citations

Age-related factors in cancers of the breast, ovary, and endometrium

1987 • 134 citations

Long-term vasectomy: effects on the occurrence and extent of atherosclerosis in rhesus monkeys.

1980 • 133 citations

Pathology, biology, and clinical staging of renal cell carcinoma.

1989 • 128 citations

Risk of Cancer after Herpes Zoster

1982 • 126 citations

Age-related effects in T cell activation and proliferation

1993 • 124 citations

Reversal of the Immunosenescent Phenotype by Dehydroepiandrosterone: Hormone Treatment Provides an Adjuvant Effect on the Immunization of Aged Mice with Recombinant Hepatitis B Surface Antigen

1993 • 124 citations

Ig VH hypermutation is absent in the germinal centers of aged mice.

1995 • 122 citations

Age-Related Decreases in IL-2 Production by Human T Cells Are Associated with Impaired Activation of Nuclear Transcriptional Factors AP-1 and NF-AT

1996 • 119 citations

Melatonin as immunompdulator in immunodeficient mice

1992 • 119 citations

Atherosclerosis induced in hypercholesterolaemic baboons by immunological injury; and the effects of intravenous polyunsaturated phosphatidyl choline

1971 • 117 citations

In vivo levels and in vitro production of interferon-gamma in fibrosing interstitial lung diseases

1992 • 116 citations

Mechanisms of age-related decline in antigen-specific T cell proliferative response: IL-2 receptor expression and recombinant IL-2 induced proliferative response of purified tac-positive T cells

1986 • 114 citations

Aging and the immune system

1997 • 109 citations

Absolute Peripheral Blood Lymphocyte Count and Subsequent Mortality of Elderly Men

1986 • 108 citations

Expression of the Macrophage Scavenger Receptor in Atheroma

1995 • 106 citations

Circadian characteristics of circulating interleukin-6 in men

1995 • 106 citations

Influences of Dietary Restriction on Immunity to Influenza in Aged Mice

1991 • 102 citations

Antitumoral properties of aged human monocytes.

1995 • 100 citations

Immune Responses Of Elderly Persons 4 Years After Receiving A Live Attenuated Varicella Vaccine

1994 • 99 citations

Effects of stress on methyltransferase synthesis: An important DNA repair enzyme.

1985 • 98 citations

Aging and immunity to tuberculosis: increased susceptibility of old mice reflects a decreased capacity to generate mediator T lymphocytes.

1987 • 95 citations

Age-Related Reductions in the Activation of Mitogen-Activated Protein Kinases p44mapk/ERK1 and p42mapk/ERK2 in Human T Cells Stimulated via Ligation of the T Cell Receptor Complex

1996 • 94 citations

A Human T-Lymphotropic Retrovirus (HTLV-III) as the Cause of the Acquired Immunodeficiency Syndrome

1985 • 89 citations

Sperm Antibodies in Vasectomized Men

1972 • 89 citations

Diminished Calcium Signal Generation in Subsets of T Lymphocytes That Predominate in Old Mice

1990 • 89 citations

Age‐Related Decline in Interleukin 2 Production in Response to Influenza Vaccine

1990 • 88 citations

Age-related changes in the capability of the bone marrow to generate B cells.

1988 • 88 citations

Age-Related Differences in Cytokine Secretion

1994 • 87 citations

Positive Correlation between H,K-Adenosine Triphosphatase Autoantibodies and Helicobacter pylori Antibodies in Patients with Pernicious Anemia

1994 • 87 citations

The effect of aging on the expression of interleukin 2 messenger ribonucleic acid

1986 • 85 citations

Stimulation of murine T cell subsets with anti-CD3 antibody. Age-related defects in the expression of early activation molecules.

1989 • 85 citations

Age-related variation in the proportion and activity of murine liver natural killer cells and their cytotoxicity against regenerating hepatocytes.

1988 • 85 citations

Increased Anti-Influenza A Virus Cytotoxic T Cell Activity following Vaccination of the Chronically III Elderly with Live Attenuated or Inactivated Influenza Virus Vaccine

1995 • 85 citations

Effects of Aging on Natural Killer Cell Activity and Activation by Interleukin-2 and IFN-α

1994 • 84 citations

Age Differences in Eicosanoid Production of Mouse Splenocytes: Effects on Mitogen-induced T-cell Proliferation

1994 • 84 citations

Age‐associated changes in mitogen‐induced protein phosphorylation in murine T lymphocytes

1992 • 82 citations

Age-associated changes in human T cell phenotype and function

1994 • 81 citations

Incidence of biopsy-proven primary glomerulonephritis in an Italian Province

1996 • 80 citations

Monokine Secretion in Aging and Protein Malnutrition

1989 • 80 citations

Should adult tetanus immunization be given as a single vaccination at age 65?

1993 • 80 citations

The Influence of an Aging Immune System on Cancer Incidence and Progression

1993 • 80 citations

Immunology and Aging

1965 • 79 citations

Dehydroepiandrosterone (DHEA) treatment reverses the impaired immune response of old mice to influenza vaccination and protects from influenza infection

1995 • 78 citations

Fever, tumor necrosis factor, and interleukin-6 in young, mature, and aged Fischer 344 rats

1992 • 76 citations

Reduced proliferation in T lymphocytes in aged humans is predominantly in the CD8+ subset, and is unrelated to defects in transmembrane signaling which are predominantly in the CD4+ subset

1989 • 73 citations

A comprehensive analysis of peripheral blood lymphocytes in healthy aged humans by flow cytometry

1993 • 72 citations

In Vitro Glutathione Supplementation Enhances Interleukin-2 Production and Mitogenic Response of Peripheral Blood Mononuclear Cells from Young and Old Subjects

1994 • 70 citations

Aging and Immunity

1992 • 70 citations

Interleukin 2, interleukin 2 receptor, and interferon-γ synthesis and mRNA expression in phorbol myristate acetate and calcium lonophore A23187-stimulated T cells from elderly humans

1989 • 69 citations

Decreased Immunity and Increased Morbidity in the Elderly

2009 • 67 citations

Splenic and inguinal lymph node T cells of aged mice respond differently to polyclonal and antigen-specific stimuli

1992 • 67 citations

Old mice are able to control low-dose aerogenic infections with Mycobacterium tuberculosis

1995 • 67 citations

Nutritional support improves antibody response to influenza virus vaccine in the elderly.

1985 • 66 citations

Myasthenia Gravis and Elderly People

1996 • 65 citations

Cytokine production and aging: overproduction of IL-8 in elderly males in response to lipopolysaccharide

1994 • 65 citations

Pineal function during aging: attenuation of the melatonin rhythm and its neurobiological consequences

1994 • 64 citations

γ-Interferon, Interleukin-4 and Interleukin-6 In Vitro Production in Old Subjects

1993 • 64 citations

Therapeutic Approaches to Varicella-Zoster Virus Infections

1992 • 64 citations

Abolished in vitro antibody response in elderly: Exclusive involvement of prostaglandin-induced T suppressor cells

1982 • 63 citations

NON-STEROIDAL ANTI-INFLAMMATORY AGENTS INHIBIT THE SYNTHESIS OF IgM RHEUMATOID FACTOR IN VITRO

1982 • 63 citations

Differential tyrosine-specific protein phosphorylation in mouse T lymphocyte subsets. Effect of age.

1993 • 63 citations

Cell proliferation and cytokine production by CD4⁺ cells from old mice

1991 • 61 citations

Effect of age on the human high affinity interleukin 2 receptor of phytohaemagglutinin stimulated peripheral blood lymphocytes.

1989 • 61 citations

DHEAS as an Effective Vaccine Adjuvant in Elderly Humans

1995 • 60 citations

Age-dependent decline in rejoining of X-ray-induced DNA double-strand breaks in normal human lymphocytes

1989 • 60 citations

Immunomodulatory Therapy With Thymopentin and Indomethacin

1991 • 60 citations

Partial reversal of the cellular immune defect in common variable immunodeficiency with indomethacin.

1978 • 59 citations

Improvement of the immunoglobulin subclass response to influenza vaccine in elderly nursing-home residents by the use of high-dose vaccines

1993 • 59 citations

Age-related alterations in the activation and expression of phosphotyrosine kinases and protein kinase C (PKC) among human B cells☆

1993 • 58 citations

Age-Related Changes in Suppressor Functions of Human T Cells

1979 • 58 citations

Loss of immune competence with age may be due to a qualitative abnormality in lymphocyte membranes

1979 • 57 citations

Bone marrow declines as a site of B-cell precursor differentiation with age: relationship to thymus involution.

1994 • 57 citations

Defective control of cytoplasmic calcium concentration in T lymphocytes from old mice

1989 • 55 citations

Lower antibody response to tetanus toxoid associated with higher auto-anti-idiotypic antibody in old compared with young humans

1993 • 54 citations

T cell activation in the elderly: Evidence for specific deficiencies in T cell/accessory cell interactions

1990 • 54 citations

Growth Hormone and the Immune Response to Bacterial Infection

1996 • 54 citations

Circulating antibodies to lung protein(s) in patients with cryptogenic fibrosing alveolitis.

1994 • 54 citations

Split-Virus Influenza Vaccines: Do They Provide Adequate Immunity in the Elderly?

1994 • 54 citations

Cytokine sensitivity of human NK cells during immunosenescence. 2. IL2-induced Interferon gamma secretion

1996 • 53 citations

First 500,000 AIDS cases—United States, 1995

1996 • 53 citations

Effect of age on the expressed B cell repertoire: role of B cell subsets

1993 • 52 citations

Immunological Functions of Aged Human Monocytes

1995 • 51 citations

Aging, immunity, and malignancy.

1970 • 51 citations

Tetanus surveillance--United States, 1989-1990.

1992 • 50 citations

Age-related decrease in frequencies of B-cell precursors and specific helper T cells involved in the IgG anti-tetanus toxoid antibody production in humans

1982 • 50 citations

Changes in lymphocyte sensitivity to prostaglandin E, histamine, hydrocortisone, and X irradiation with age: Studies in a healthy elderly population

1982 • 49 citations

Humoral and cellular immune response to influenza virus vaccination in aged humans

1993 • 49 citations

Effect of diet and plasma fatty acid composition on immune status in elderly men

1994 • 47 citations

Distribution of non-Hodgkin's lymphoma in the United States between 1950 and 1975.

1980 • 47 citations

In vivo immunopotentiating activity of thymopentin in aging humans: Increase of Il-2 production

1987 • 46 citations

Localisation of a pulmonary autoantigen in cryptogenic fibrosing alveolitis.

1994 • 46 citations

Decreased specific antibody synthesis in old adults: Decreased potency of antigen-specific B cells with aging

1990 • 45 citations

Age and Dose Related Alteration of in Vitro Mixed Lymphocyte Culture Response of Blood Lymphocytes from A-Bomb Survivors

1989 • 45 citations

Enhanced frequency of mitogen‐responsive T cell precursors in old mice injected with thymosin α₁

1987 • 45 citations

Reduced Activation of Transcriptional Factor AP-1 among Peripheral Blood T Cells from Elderly Humans after PHA Stimulation: Restorative Effect of Phorbol Diesters

1993 • 45 citations

Age-related increase in the fraction of CD27−CD4+ T cells and IL-4 production as a feature of CD4+ T cell differentiationin vivo

1994 • 45 citations

Immunology and Infectious Disease

1990 • 45 citations

Follicular dendritic cells in the alternative antigen transport pathway: microenvironment, cellular events, age and retrovirus related alterations.

1992 • 44 citations

Current status and prospects of live varicella vaccine

1992 • 44 citations

Dysregulation of the humoral immune response in old mice

1995 • 43 citations

Evidence for a Defective Accumulation of Protective T Cells in Old Mice Infected with Mycobacterium tuberculosis

1993 • 42 citations

Age-associated changes in proliferative and differentiative response of human B cells and production of T cell-derived factors regulating B cell functions

1987 • 41 citations

Human B cel proliferative responses during aging. Reduced RNA synthesis and DNA replication after signal transduction by surface immunoglobulins compared to B cell antigenic determinants CD20 and CD40

1991 • 40 citations

Recombinant Vaccinia Virus Expressing the PR/8 Influenza Hemagglutinin Gene Overcomes the Impaired Immune Response and Increased Susceptibility of Old Mice to Influenza Infection

1993 • 39 citations

Altered major histocompatibility complex‐restricted antigen recognition by T cells from elderly humans

1992 • 39 citations

Age-related impairment of the in vitro antibody response in the human.

1980 • 38 citations

Clonally Expanded CD8 T Cells in Patients with Polymyalgia Rheumatica and Giant Cell Arteritis

1996 • 38 citations

Cytotoxic T Lymphocyte Responses to a Liposome-Adjuvanted Influenza A Virus Vaccine in the Elderly

1995 • 37 citations

Acquired Immunodeficiency Syndrome in the Elderly

1994 • 37 citations

Age-Associated Decline in IL-4 Production by Murine T Lymphocytes in Extended Culture

1993 • 37 citations

Aging and the Mobilization of Intracellular Calcium by Phytohemagglutinin in Human T Cells

1989 • 35 citations

Age-related changes of expression of IL-2 receptor subunits and kinetics of IL-2 internalization in T cells after mitogenic stimulation

1988 • 34 citations

Immunosenescence: Clinical and Pharmacologic Considerations

1985 • 34 citations

Differential expression of the α- and β-isoforms of protein kinase C in peripheral blood T and B cells from young and elderly adults

1995 • 34 citations

V_H‐Gene Family Dominance in Ageing Mice

1994 • 34 citations

Comparison of one- and two-dose regimens of influenza vaccine for elderly men.

1987 • 34 citations

Life events and illness onset: A review

1978 • 32 citations

Effect of synthetic thymic humoral factor (THF-γ2) on T cell activities in immunodeficient ageing mice

1992 • 31 citations

Chromosomes of older humans are more prone to aminopterine-induced breakage.

1989 • 31 citations

Differential Expression of Various T Cell Surface Markers in Young and Elderly Subjects

1995 • 31 citations

Specific antibody synthesis in vitro. II. Age-associated thymosin enhancement of antitetanus antibody synthesis

1984 • 31 citations

Diet Nutrition and Immunity

1994 • 31 citations

Thymopentin reduces the susceptibility of aged mice to cutaneous leishmaniasis by modulating CD4 T-cell subsets.

1992 • 30 citations

Nutrition is an important determinant of immunity in old age.

1990 • 29 citations

First 500 000 AIDS Cases-United States, 1995

1995 • 29 citations

The Immunoepidemiology of Aging

1977 • 28 citations

Functional analysis of the immunosenescence of the human B cell system: dissociation of normal activation and proliferation from impaired terminal differentiation into IgM immunoglobulin-secreting cells.

1986 • 28 citations

A Neuroendocrine-Immune Theory of Aging

1990 • 28 citations

Progress in Gerontology: Polymyalgia Rheumatica and Temporal Arteritis

1992 • 27 citations

A randomized study of neuroimmunotherapy with low-dose subcutaneous interleukin-2 plus melatonin compared to supportive care alone in patients with untreatable metastatic solid tumour

1995 • 27 citations

Mel14⁺CD4⁺ T cells from aged mice display functional and phenotypic characteristics of memory cells

1994 • 27 citations

Human Gastric H,K-Adenosine Triphosphatase β-Subunit Is a Major Autoantigen in Atrophic Corpus Gastritis: Expression of the Recombinant Human Glycoprotein in Insect Cells

1994 • 27 citations

Transmembrane Signaling Changes with Aging^a

1992 • 27 citations

The in vivo effects of neutralizing antibodies against IFN-γ, IL-4, or IL-10 on the humoral immune response in young and aged mice

1995 • 26 citations

The relationship between white blood cells and arterial disease

1994 • 25 citations

Mechanisms Underlying the Increased Susceptibility of Aged Mice to Tuberculosis

2009 • 25 citations

Analysis of the age-related decline in alloreactivity of CD4+ and CD8+ T cells in CBA/Rij mice

1990 • 24 citations

Basal Natural Killer Cell Activity of Young versus Elderly Humans

1995 • 24 citations

Modulation of immune response in aged humans through different administration modes of thymopentin

1985 • 24 citations

LYMPHOCYTE SUBPOPULATIONS ANALYSIS IN PERIPHERAL BLOOD IN POLYMYALGIA RHEUMATICA/GLANT CELL ARTERITIS

1993 • 23 citations

Age-related decrease in the number of hemopoietic stem cells and progenitors in senescence accelerated mice

1990 • 23 citations

Immune effects of preoperative immunotherapy with high-dose subcutaneous interleukin-2 versus neuroimmunotherapy with low-dose interleukin-2 plus the neurohormone melatonin in gastrointestinal tract tumor patients.

1995 • 23 citations

Secretion of cytokines upon allogeneic stimulation: effect of aging.

1994 • 23 citations

Factors influencing the secondary antibody response to flagellin in man.

1978 • 22 citations

Insulin-like growth factor I is an independent coregulatory modulator of natural killer (NK) cell activity.

1996 • 22 citations

Calcium signals in T lymphocytes from old mice

1996 • 22 citations

Management of tetanus in the elderly.

1992 • 22 citations

Age restriction in antigen-specific immunosuppression.

1987 • 21 citations

Age-related changes of the antigen-specific antibody formation in vitro and PHA-induced T-cell proliferation in individuals who met the health criteria of the senieur protocol

1992 • 21 citations

A decreased functional capacity of CD4+ T cells underlies the impaired DTH reactivity in old mice

1990 • 19 citations

Sister chromatid exchange and proliferation pattern in lymphocytes from newborns, elderly subjects and in premature aging syndromes

1990 • 19 citations

Augmentation of the immune response to influenza vaccine by acetylsalicylic acid: a clinical trial in a geriatric population.

1994 • 19 citations

Age associated changes in mitogen induced proliferation and cytokine production by lymphocytes of the long-lived Brown Norway rat

1993 • 18 citations

Diminished Cell-Cell Binding by Lymphocytes from Healthy, Elderly Humans: Evidence for Altered Activation of LFA-1 Function With Age

1995 • 18 citations

Antibody Protection in Aging: Influence of Idiotypic Repertoire and Antibody Binding Activity to a Bacterial Antigen

1995 • 18 citations

Natural killer cell cytotoxicity in elderly humans after influenza immunization

1996 • 18 citations

Impaired humoral immune responses to mycobacterial antigen in aged murine gut-associated lymphoid tissues

1990 • 18 citations

Effect of host age upon interleukin-2-mediated anti-tumor responses in a murine fibrosarcoma model

1990 • 17 citations

Production of anti-acetylcholine receptor-alpha antibody in vitro by peripheral blood lymphocytes of patients with myasthenia gravis: role of immunoregulatory T cells and monocytes.

1994 • 16 citations

Age-dependent appearance of non-major histocompatibility complex-restricted helper T cells.

1993 • 16 citations

Tetanus in Switzerland 1980?1989

1993 • 15 citations

In vivo immunologic intervention in age-related T cell defects in murine gut-associated lymphoid tissues by IL2

1990 • 15 citations

Biology of Aging: Retrospect and Prospect

1977 • 15 citations

An In Vitro Analogue of Immune Dysfunction with Altered Immunoglobulin Production in the Aged

1989 • 14 citations

The Use of Monozygotic and Dizygotic Twins to Estimate the Effects of Inheritance on the Levels of Immunoglobulin Isotypes and Antibodies to Phosphocholine

1993 • 14 citations

Impaired autoreactive T cell-induced T cell-T cell interaction in aged mice

1988 • 13 citations

Effects of Growth Hormone and Estrogen on T Lymphocytes in Older Women

1996 • 13 citations

IgD‐receptor up‐regulation on human peripheral blood T cells in response to IgD in vitro or antigen in vivo correlates with the antibody response to influenza vaccination

1996 • 13 citations

T and B lymphocytes reacting with the extracellular loop of the β2-adrenergic receptor (β2AR) are present in the peripheral blood of patients with myasthenia gravis

1996 • 13 citations

Postherpetic neuralgia: current concepts and management.

1994 • 12 citations

Tetanus

1992 • 12 citations

Cancer and age.

1989 • 11 citations

Increase of cross(auto)-reactive antibodies after immunization in aged mice: a cellular and molecular study.

1994 • 11 citations

Modulation of IL-2, IFN-γ, TNF-α and IL-4 production in mice of different ages by thymopentin

1992 • 10 citations

Effects of interleukin-4 on antigen-specific antibody synthesis by lymphocytes from old and young adults.

1994 • 10 citations

Morphological fate and sequelae of human atherosclerosis: Evaluation of immune mechanisms in atherogenesis through immunohistological and ultrastructural analysis

1995 • 10 citations

Relationship between Humoral Immunoaugmenting Properties of DHEAS and IgD‐Receptor Expression in Young and Aged Mice^a

1995 • 10 citations

Tetanus in Auckland: a preventable disease.

1994 • 8 citations

Characterization and immunogenicity of a candidate subunit vaccine against varicella-zoster virus

1994 • 8 citations

Effects of prostaglandin E1 on the production of IgM and IgG class anti-dsDNA antibodies in NZB/W F1 mice.

1993 • 7 citations

Enrichment for Th1 Cells in the Mel-14+ CD4+ T Cell Fraction in Aged Mice

1995 • 7 citations

IVth INTERNATIONAL AIDS CONFERENCE

1988 • 6 citations

Complement levels in the squirrel monkey (Saimiri sciureus).

1982 • 5 citations

Psychological status and immunological parameters of institutionalized aged.

1991 • 5 citations

Adult vaccinations: protecting your patients from avoidable illness.

1993 • 4 citations

Treatment of herpes simplex and varicella zoster infections.

1994 • 1 citations

Deleted Work

1955 • 0 citations