Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

Muscarinic activation of ionic currents measured by a new whole-cell recording method.

1988 • 1,777 citations

Depletion of intracellular calcium stores activates a calcium current in mast cells

1992 • 1,748 citations

Capacitative calcium entry revisited

1990 • 1,499 citations

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps.

1991 • 1,282 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

1989 • 887 citations

The variance of sodium current fluctuations at the node of Ranvier

1980 • 772 citations

‘Quanta’ Ca²⁺ release and the control of Ca²⁺ entry by inositol phosphates ‐ a possible mechanism

1990 • 743 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

CALCIUM CHANNELS: Mechanisms of Selectivity, Permeation, and Block

1987 • 528 citations

CONDUCTANCE FLUCTUATIONS AND IONIC PORES IN MEMBRANES

1977 • 510 citations

Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.

1989 • 402 citations

Inositol 1,4,5-trisphosphate activates a channel from smooth muscle sarcoplasmic reticulum

1988 • 399 citations

Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.

1991 • 351 citations

Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.

1990 • 292 citations

Coupling between intracellular Ca2+ stores and the Ca2+ permeability of the plasma membrane. Comparison of the effects of thapsigargin, 2,5-di-(tert-butyl)-1,4-hydroquinone, and cyclopiazonic acid in rat thymic lymphocytes.

1991 • 243 citations

IP ₃ Receptor: Localization to Plasma Membrane of T Cells and Cocapping with the T Cell Receptor

1992 • 213 citations

Early Signal Transduction by the Antigen Receptor Without Commitment to T Cell Activation

1988 • 169 citations

Second messenger‐activated calcium influx in rat peritoneal mast cells.

1989 • 163 citations

Single-channel and whole-cell recordings of mitogen-regulated inward currents in human cloned helper T lymphocytes

1986 • 151 citations

Ca(2+)-activated K+ channels in human leukemic T cells.

1992 • 128 citations

Plasma membrane inositol 1,4,5-trisphosphate receptor of lymphocytes: selective enrichment in sialic acid and unique binding specificity.

1992 • 120 citations

Ca²⁺ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca²⁺ stores. A study with the Ca²⁺ endoplasmic reticulum‐ATPase inhibitor thapsigargin

1990 • 106 citations

Comparison between the effects of the microsomal Ca2+-translocase inhibitors thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone on cellular calcium fluxes

1991 • 89 citations

Distinct patterns of transmembrane calcium flux and intracellular calcium mobilization after differentiation antigen cluster 2 (E rosette receptor) or 3 (T3) stimulation of human lymphocytes.

1986 • 89 citations

The role of intracellular Ca2+ in the regulation of the plasma membrane Ca2+ permeability of unstimulated rat lymphocytes

1991 • 82 citations

Regulation of CI− channels by multifunctional CaM kinase

1991 • 68 citations

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relations to AIDS

1988 • 55 citations

Triggering of T-lymphocytes via Either T3-Ti or T11 Surface Structures Opens a Voltage-insensitive Plasma Membrane Calcium-permeable Channel: Requirement for Interleukin-2 Gene Function

1989 • 46 citations

Calcium influx and intracellular calcium release in anti-CD3 antibody-stimulated and thapsigargin-treated human T lymphoblasts

1991 • 41 citations