V_H‐Gene Family Dominance in Ageing Mice

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A plaque assay for all cells secreting Ig of a given type or class

1976 • 1,034 citations

Age Influence on the Immune System

1980 • 703 citations

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

1984 • 644 citations

A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells

1983 • 561 citations

B220: a B cell-specific member of the T200 glycoprotein family

1981 • 525 citations

Aging and Immune Function

1991 • 361 citations

The Cellular and Subcellular Bases of Immunosenescence

1989 • 326 citations

Developmentally regulated and strain-specific expression of murine VH gene families.

1988 • 186 citations

Idiotype‐Directed Interactions during Ontogeny Play a Major Role in the Establishment of the Adult B Cell Repertoire

1986 • 166 citations

Frequencies of mitogen-reactive B cells in the mouse. I. Distribution in different lymphoid organs from different inbred strains of mice at different ages

1977 • 158 citations

The Generation of Diversity in Phosphorylcholine-Binding Antibodies

1984 • 153 citations

Comparison of the fetal and adult functional B cell repertoires by analysis of VH gene family expression.

1988 • 104 citations

The genetic control of antibody variable regions in the mouse

1978 • 95 citations

Repertoire diversity of antibody response to bacterial antigens in aged mice. II. Phosphorylcholine-antibody in young and aged mice differ in both VH/VL gene repertoire and in specificity.

1991 • 91 citations

A monoclonal antibody against Igh6-4 determinant

1986 • 88 citations

High connectivity, natural antibodies preferentially use 7183 and QUPC52 V_H families

1987 • 88 citations

Altered VH gene segment utilization in the response to phosphorylcholine by aged mice.

1989 • 76 citations

A new murine Ig VH gene family.

1988 • 75 citations

The Senescence of the Immune System

1981 • 75 citations

Selection of V_H gene repertoires: differentiating B cells of adult bone marrow mimic fetal development

1990 • 74 citations

Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice.

1987 • 72 citations

Expression of antibody V-regions is genetically and developmentally controlled and modulated by the B lymphocyte environment

1989 • 70 citations

Frequencies of background immunoglobulin-secreting cells in mice as a function of organ, age, and immune status

1981 • 59 citations

A selective increase in the generation of phosphorylcholine-specific B cells associated with aging.

1986 • 50 citations

Immunoglobulin V_H gene expression in Ly‐1⁺ and conventional B lymphocytes

1989 • 37 citations

Differential expression of VH gene families in peripheral B cell repertoires of newborn or adult immunoglobulin H chain congenic mice.

1992 • 35 citations

Cellular basis for the age-associated increase in autoimmune reactions

1990 • 31 citations

Selection of antibody repertoires: transfer of mature T lymphocytes modifies V_H gene family usage in the actual and available B cell repertoires of athymic mice

1989 • 22 citations