DNA viruses and viral proteins that interact with PML nuclear bodies

RING Finger Proteins

2000 • 1,216 citations

SUMO-1 Modification of IκBα Inhibits NF-κB Activation

1998 • 1,002 citations

Pml Is Critical for Nd10 Formation and Recruits the Pml-Interacting Protein Daxx to This Nuclear Structure When Modified by Sumo-1

1999 • 809 citations

A new protease required for cell-cycle progression in yeast

1999 • 718 citations

Efficient Persistence of Extrachromosomal KSHV DNA Mediated by Latency-Associated Nuclear Antigen

1999 • 691 citations

Ubiquitination: RING for destruction?

2000 • 496 citations

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

1997 • 484 citations

Role of Promyelocytic Leukemia (Pml) Sumolation in Nuclear Body Formation, 11s Proteasome Recruitment, and as2O3-Induced Pml or Pml/Retinoic Acid Receptor α Degradation

2001 • 477 citations

The Disruption of ND10 during Herpes Simplex Virus Infection Correlates with the Vmw110- and Proteasome-Dependent Loss of Several PML Isoforms

1998 • 402 citations

Sequestration and Inhibition of Daxx-Mediated Transcriptional Repression by PML

2000 • 357 citations

HSV-1 IE protein Vmw110 causes redistribution of PML.

1994 • 354 citations

The Latency-Associated Nuclear Antigen Tethers the Kaposi's Sarcoma-Associated Herpesvirus Genome to Host Chromosomes in Body Cavity-Based Lymphoma Cells

1999 • 351 citations

The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition.

1996 • 336 citations

Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins

1999 • 330 citations

Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0)

1993 • 316 citations

EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins.

1993 • 312 citations

Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

1996 • 307 citations

Visualization of gene activity in living cells

2000 • 305 citations

Viral Immediate-Early Proteins Abrogate the Modification by SUMO-1 of PML and Sp100 Proteins, Correlating with Nuclear Body Disruption

1999 • 303 citations

ICP0, a regulator of herpes simplex virus during lytic and latent infection

2000 • 297 citations

Review: Properties and Assembly Mechanisms of ND10, PML Bodies, or PODs

2000 • 286 citations

The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0

1994 • 281 citations

Nuclear domain 10, the site of DNA virus transcription and replication

1998 • 273 citations

Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)

1999 • 273 citations

Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

1998 • 269 citations

Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

1995 • 261 citations

Nuclear Domain 10 as Preexisting Potential Replication Start Sites of Herpes Simplex Virus Type-1

1996 • 261 citations

The Nuclear Dot Protein Sp100, Characterization of Domains Necessary for Dimerization, Subcellular Localization, and Modification by Small Ubiquitin-like Modifiers

1999 • 258 citations

Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 Induces the Proteasome-Dependent Degradation of the Catalytic Subunit of DNA-Dependent Protein Kinase

1999 • 255 citations

Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110

1999 • 251 citations

The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells

1997 • 250 citations

Epstein-Barr Virus Immediate-Early Protein BZLF1 Is SUMO-1 Modified and Disrupts Promyelocytic Leukemia Bodies

2001 • 225 citations

Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon

2000 • 218 citations

A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation.

1996 • 214 citations

Intracellular Localization of Proteasomal Degradation of a Viral Antigen

1999 • 214 citations

The Nuclear Domain 10 (ND10) Is Disrupted by the Human Cytomegalovirus Gene Product IE1

1996 • 213 citations

Human Cytomegalovirus Immediate Early Interaction with Host Nuclear Structures: Definition of an Immediate Transcript Environment

1997 • 205 citations

The Papillomavirus Minor Capsid Protein, L2, Induces Localization of the Major Capsid Protein, L1, and the Viral Transcription/Replication Protein, E2, to PML Oncogenic Domains

1998 • 203 citations

Cell cycle regulation of PML modification and ND10 composition

1999 • 190 citations

Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation

1998 • 182 citations

ICP0 Is Required for Efficient Reactivation of Herpes Simplex Virus Type 1 from Neuronal Latency

2001 • 182 citations

Chromatin components as part of a putative transcriptional repressing complex

1998 • 179 citations

Disruption of PML Subnuclear Domains by the Acidic IE1 Protein of Human Cytomegalovirus Is Mediated through Interaction with PML and May Modulate a RING Finger-Dependent Cryptic Transactivator Function of PML

1998 • 176 citations

Alphaherpesvirus Proteins Related to Herpes Simplex Virus Type 1 ICP0 Affect Cellular Structures and Proteins

2000 • 174 citations

Covalent Modification of the Transactivator Protein IE2-p86 of Human Cytomegalovirus by Conjugation to the Ubiquitin-Homologous Proteins SUMO-1 and hSMT3b

2000 • 167 citations

Degradation of Nucleosome-associated Centromeric Histone H3-like Protein CENP-A Induced by Herpes Simplex Virus Type 1 Protein ICP0

2001 • 166 citations

Origin-Independent Assembly of Kaposi's Sarcoma-Associated Herpesvirus DNA Replication Compartments in Transient Cotransfection Assays and Association with the ORF-K8 Protein and Cellular PML

2001 • 159 citations

Repression of viral transcription during herpes simplex virus latency

2000 • 159 citations

Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product.

1998 • 132 citations

Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation

2001 • 131 citations

Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System

1999 • 130 citations

Disruption of PML-Associated Nuclear Bodies by IE1 Correlates with Efficient Early Stages of Viral Gene Expression and DNA Replication in Human Cytomegalovirus Infection

2000 • 128 citations

The Human Cytomegalovirus IE2 and UL112-113 Proteins Accumulate in Viral DNA Replication Compartments That Initiate from the Periphery of Promyelocytic Leukemia Protein-Associated Nuclear Bodies (PODs or ND10)

1999 • 126 citations

Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 Inhibits Progression of Cells through Mitosis and from G ₁ into S Phase of the Cell Cycle

1999 • 122 citations

The Ability of Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 To Bind to a Ubiquitin-Specific Protease Contributes to Its Roles in the Activation of Gene Expression and Stimulation of Virus Replication

1999 • 122 citations

A viral activator of gene expression functions via the ubiquitin-proteasome pathway

1998 • 119 citations

Interaction of the Papillomavirus E2 Protein with Mitotic Chromosomes

2000 • 119 citations

The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components.

1999 • 116 citations

A dynamic connection between centromeres and ND10 proteins

1999 • 107 citations

ICP0 Induces the Accumulation of Colocalizing Conjugated Ubiquitin

2000 • 106 citations

The DNA segregation mechanism of Epstein–Barr virus nuclear antigen 1

2000 • 102 citations

Lytic but Not Latent Replication of Epstein-Barr Virus Is Associated with PML and Induces Sequential Release of Nuclear Domain 10 Proteins

2000 • 101 citations

Evaluation of Interactions of Human Cytomegalovirus Immediate-Early IE2 Regulatory Protein with Small Ubiquitin-Like Modifiers and Their Conjugation Enzyme Ubc9

2001 • 101 citations

ND10 Protein PML Is Recruited to Herpes Simplex Virus Type 1 Prereplicative Sites and Replication Compartments in the Presence of Viral DNA Polymerase

1998 • 99 citations

Disruption of PML-associated nuclear bodies during human cytomegalovirus infection

1995 • 96 citations

Interferon γ regulates accumulation of the proteasome activator PA28 and immunoproteasomes at nuclear PML bodies

2001 • 85 citations

Formation of herpes simplex virus type 1 replication compartments by transfection: requirements and localization to nuclear domain 10

1997 • 78 citations

Replication but Not Transcription of Simian Virus 40 DNA Is Dependent on Nuclear Domain 10

2000 • 76 citations

Interactions of Herpes Simplex Virus Type 1 with ND10 and Recruitment of PML to Replication Compartments

2001 • 68 citations

Interaction of the Papillomavirus Transcription/Replication Factor, E2, and the Viral Capsid Protein, L2

2000 • 61 citations

Efficient Activation of Viral Genomes by Levels of Herpes Simplex Virus ICP0 Insufficient To Affect Cellular Gene Expression or Cell Survival

2001 • 54 citations

Non-apoptotic chromosome condensation induced by stress: delineation of interchromosomal spaces

2000 • 29 citations

Alphaherpesvirus Proteins Related to Herpes Simplex Virus Type 1 ICP0 Induce the Formation of Colocalizing, Conjugated Ubiquitin

2001 • 29 citations

A surprising role for the proteasome in the regulation of herpesvirus infection

1999 • 26 citations

Interferon Coordinately Inhibits the Disruption of PML-Positive ND10 and Immediate-Early Gene Expression by Herpes Simplex Virus

2000 • 24 citations

Human Neuron-Committed Teratocarcinoma NT2 Cell Line Has Abnormal ND10 Structures and Is Poorly Infected by Herpes Simplex Virus Type 1

2001 • 23 citations

Intranuclear Redistribution of SV40T, p53, and PML in a Conditionally SV40T-Immortalized Cell Line

1996 • 22 citations