Degradation of Nucleosome-associated Centromeric Histone H3-like Protein CENP-A Induced by Herpes Simplex Virus Type 1 Protein ICP0

Pml Is Critical for Nd10 Formation and Recruits the Pml-Interacting Protein Daxx to This Nuclear Structure When Modified by Sumo-1

1999 • 809 citations

Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma

1985 • 803 citations

Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK

1979 • 496 citations

Herpes simplex virus type 1 ICP27 is an essential regulatory protein

1985 • 462 citations

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere.

1994 • 444 citations

Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4

1981 • 436 citations

Isolation and Characterization of a Herpes Simplex Virus Type 1 Mutant Containing a Deletion within the Gene Encoding the Immediate Early Polypeptide Vmw110

1986 • 422 citations

The Disruption of ND10 during Herpes Simplex Virus Infection Correlates with the Vmw110- and Proteasome-Dependent Loss of Several PML Isoforms

1998 • 402 citations

A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones

1987 • 401 citations

Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

2000 • 388 citations

Persistence and Expression of the Herpes Simplex Virus Genome in the Absence of Immediate-Early Proteins

1998 • 373 citations

Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency

1989 • 372 citations

HSV-1 IE protein Vmw110 causes redistribution of PML.

1994 • 354 citations

The Centromere: Hub of Chromosomal Activities

1995 • 353 citations

PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia.

1996 • 347 citations

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

1992 • 340 citations

A generalized technique for deletion of specific genes in large genomes: a gene 22 of herpes simplex virus 1 is not essential for growth

1981 • 336 citations

Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres

1997 • 336 citations

The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition.

1996 • 336 citations

Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins

1999 • 330 citations

The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation.

1992 • 318 citations

Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0)

1993 • 316 citations

Viral Immediate-Early Proteins Abrogate the Modification by SUMO-1 of PML and Sp100 Proteins, Correlating with Nuclear Body Disruption

1999 • 303 citations

During latency, herpes simplex virus type 1 DNA is associated with nucleosomes in a chromatin structure

1989 • 301 citations

Heterochromatic deposition of centromeric histone H3-like proteins

2000 • 298 citations

ICP0, a regulator of herpes simplex virus during lytic and latent infection

2000 • 297 citations

Assembly of CENP-A into Centromeric Chromatin Requires a Cooperative Array of Nucleosomal DNA Contact Sites

1997 • 295 citations

Identification of a novel nuclear domain.

1991 • 285 citations

The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0

1994 • 281 citations

Experimental investigation of herpes simplex virus latency

1997 • 275 citations

Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)

1999 • 273 citations

Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

1998 • 269 citations

Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 Induces the Proteasome-Dependent Degradation of the Catalytic Subunit of DNA-Dependent Protein Kinase

1999 • 255 citations

Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110

1999 • 251 citations

CENP-B: a major human centromere protein located beneath the kinetochore.

1990 • 238 citations

CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase.

1994 • 200 citations

Chromatin components as part of a putative transcriptional repressing complex

1998 • 179 citations

Construction and Characterization of Herpes Simplex Virus Type 1 Mutants with Defined Lesions in Immediate Early Gene 1

1989 • 177 citations

Alphaherpesvirus Proteins Related to Herpes Simplex Virus Type 1 ICP0 Affect Cellular Structures and Proteins

2000 • 174 citations

Chromatin containing CENP-A and α-satellite DNA is a major component of the inner kinetochore plate

1997 • 160 citations

Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis.

1990 • 147 citations

The cenpB gene is not essential in mice

1998 • 137 citations

Herpes simplex virus type 1 immediate-early protein Vmw110 reactivates latent herpes simplex virus type 2 in an in vitro latency system

1989 • 132 citations

Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 Inhibits Progression of Cells through Mitosis and from G ₁ into S Phase of the Cell Cycle

1999 • 122 citations

Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death

1998 • 122 citations

The Ability of Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 To Bind to a Ubiquitin-Specific Protease Contributes to Its Roles in the Activation of Gene Expression and Stimulation of Virus Replication

1999 • 122 citations

Centromerization

2000 • 112 citations

A dynamic connection between centromeres and ND10 proteins

1999 • 107 citations

ICP0 Induces the Accumulation of Colocalizing Conjugated Ubiquitin

2000 • 106 citations

A Truncated Form of Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 Is Expressed in a Cell Type Dependent Manner

1993 • 104 citations

Alphoid satellite DNA is tightly associated with centromere antigens in human chromosomes throughout the cell cycle

1989 • 104 citations

Reactivation of latent herpes simplex virus by adenovirus recombinants encoding mutant IE-0 gene products

1990 • 95 citations

A Herpes Simplex Virus Type 1 Mutant Containing a Deletion within Immediate Early Gene 1 Is Latency-competent in Mice

1989 • 95 citations

Repression of gene expression upon infection of cells with herpes simplex virus type 1 mutants impaired for immediate-early protein synthesis

1997 • 94 citations

Chromosomal organization of the herpes simplex virus genome during acute infection of the mouse central nervous system

1986 • 73 citations

A novel centromere monospecific serum to a human autoepitope on the histone H3‐like protein CENP‐A

1998 • 33 citations