The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1998 • 676 citations

Isolation and Characterization of a Herpes Simplex Virus Type 1 Mutant Containing a Deletion within the Gene Encoding the Immediate Early Polypeptide Vmw110

1986 • 422 citations

The Disruption of ND10 during Herpes Simplex Virus Infection Correlates with the Vmw110- and Proteasome-Dependent Loss of Several PML Isoforms

1998 • 402 citations

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1985 • 383 citations

HSV-1 IE protein Vmw110 causes redistribution of PML.

1994 • 354 citations

PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia.

1996 • 347 citations

The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition.

1996 • 336 citations

Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture

1987 • 333 citations

Evidence for Covalent Modification of the Nuclear Dot–associated Proteins PML and Sp100 by PIC1/SUMO-1

1997 • 329 citations

Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0)

1993 • 316 citations

Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

1996 • 307 citations

The Adenovirus E1B-55K Transforming Polypeptide Modulates Transport or Cytoplasmic Stabilization of Viral and Host Cell mRNAs

1986 • 301 citations

Identification of a novel nuclear domain.

1991 • 285 citations

The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0

1994 • 281 citations

Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

1995 • 261 citations

Redundant control of adenovirus late gene expression by early region 4

1989 • 261 citations

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport.

1985 • 234 citations

Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

1984 • 221 citations

Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein

1983 • 197 citations

Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence

1997 • 186 citations

The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism.

1989 • 169 citations

Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein

1991 • 154 citations

The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA binding activity of the cellular transcription factor, E2F, through a direct complex.

1989 • 148 citations

Localization of the E1 B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies

1985 • 145 citations

Interaction of adenoviral E4 and E1b products in late gene expression

1990 • 143 citations

A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2.

1983 • 141 citations

The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex.

1994 • 136 citations

The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle

1997 • 127 citations

Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells

1987 • 120 citations

E4 gene function in adenovirus, adenovirus vector and adeno-associated virus infections.

1997 • 118 citations

Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix

1982 • 102 citations

Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells

1996 • 101 citations

Disruption of PML-associated nuclear bodies during human cytomegalovirus infection

1995 • 96 citations

Identification of the adenovirus early proteins and their genomic map positions

1980 • 83 citations

Human adenovirus encodes two proteins which have opposite effects on accumulation of alternatively spliced mRNAs.

1994 • 81 citations

Early region 1B of adenovirus 2 encodes two coterminal proteins of 495 and 155 amino acid residues

1984 • 65 citations

Two Adenovirus Proteins with Redundant Activities in Virus Growth Facilitates Tripartite Leader mRNA Accumulation

1993 • 61 citations

Post-transcriptional Control of Adenovirus Gene Expression

1995 • 58 citations

Organization of early region 1B of human adenovirus type 2: identification of four differentially spliced mRNAs

1985 • 56 citations

Mapping of a 14,000-dalton antigen to early region 4 of the human adenovirus 5 genome

1983 • 47 citations

RNA-Binding Activity of the E1B 55-Kilodalton Protein from Human Adenovirus Type 5

1998 • 38 citations

Selective effects on adenovirus late gene expression of deleting the E1b 55K protein

1993 • 28 citations

Regulated RNA Processing and RNA Transport during Adenovirus Infection

1998 • 27 citations

Human adenovirus type 5 recombinants expressing simian immunodeficiency virus macaque strain gag antigens

1993 • 14 citations