Sequence of the human insulin gene

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Atlas of protein sequence and structure

1965 • 4,462 citations

Atlas of Protein Sequence and Structure, 1966.

1967 • 1,463 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Virus-Induced Diabetes Mellitus

1979 • 1,011 citations

The internal secretion of the pancreas

1922 • 800 citations

Membrane Receptors

1974 • 636 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites

1978 • 409 citations

Physiology of Insulin In Man: The Banting Memorial Lecture 1971

1971 • 353 citations

Organisation and sequences at the 5′ end of a cloned complete ovalbumin gene

1979 • 340 citations

The evolution and sequence comparison of two recently diverged mouse chromosomal β-globin genes

1979 • 337 citations

The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution

1979 • 317 citations

Molecular Basis of Insulin Action

1985 • 309 citations

Cell-free synthesis of rat preproinsulins: characterization and partial amino acid sequence determination.

1976 • 279 citations

Isolation and characterization of a cloned rat insulin gene

1979 • 229 citations

Growth and maintenance of HeLa cells in serum-free medium supplemented with hormones.

1978 • 208 citations

Splicing as a requirement for biogenesis of functional 16S mRNA of simian virus 40.

1979 • 185 citations

Cell-free synthesis of fish preproinsulin, and processing by heterologous mammalian microsomal membranes.

1977 • 182 citations

A structurally abnormal insulin causing human diabetes

1979 • 180 citations

The Diabetic Pancreas

1977 • 173 citations

The dna sequence of bombyx mori fibroin gene including the 5′ flanking, mRNA coding, entire intervening and fibroin protein coding regions

1979 • 165 citations

Comparison of cloned rabbit and mouse β-globin genes showing strong evolutionary divergence of two homologous pairs of introns

1978 • 156 citations

INSULIN BIOSYNTHESIS IN THE RAT: DEMONSTRATION OF TWO PROINSULINS

1969 • 155 citations

Nucleotide sequence of a cDNA clone encoding human preproinsulin

1979 • 141 citations

Peptide Hormones

1974 • 121 citations

Current Views on the Etiology of Insulin-Dependent Diabetes Mellitus

1978 • 112 citations

The Causes of Diabetes

1979 • 95 citations

Processing of the mouse β-globin mRNA precursor: at least two cleavage-ligation reactions are necessary to excise the larger intervening sequence

1979 • 84 citations

Buoyant densities of DNA of mammals

1970 • 69 citations

Application of recombinant DNA technology to questions of developmental biology: A review

1979 • 65 citations

Immunological and chemical characterization of bovine preproinsulin.

1977 • 60 citations

Related base sequences in the DNA of simple and complex organisms. VI. The extent of base sequence divergence among the DNAs of various rodents

1970 • 60 citations

Familial hyperproinsulinemia: partial characterization of circulating proinsulin-like material.

1979 • 48 citations

Chemically and Hormonally Induced Diabetes

1977 • 48 citations

Synthesis and Accumulation of Proinsulin and Insulin during Development of the Embryonic Rat Pancreas*

1979 • 28 citations

Insulin of Spiny Mice (Acomys cahirinus)–Partial Characterization and Evidence for Two Insulins

1971 • 8 citations