The evolution of genes: the chicken preproinsulin gene

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning

1977 • 951 citations

Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone

1977 • 532 citations

The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions

1980 • 531 citations

Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone

1979 • 517 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

The primary structure of rabbit β-globin mRNA as determined from cloned DNA

1977 • 428 citations

Human Growth Hormone: Complementary DNA Cloning and Expression in Bacteria

1979 • 399 citations

Organisation and sequences at the 5′ end of a cloned complete ovalbumin gene

1979 • 340 citations

The evolution and sequence comparison of two recently diverged mouse chromosomal β-globin genes

1979 • 337 citations

The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution

1979 • 317 citations

Splicing and the formation of stable RNA

1979 • 274 citations

Comparison of Total Sequence of a Cloned Rabbit β-Globin Gene and Its Flanking Regions with a Homologous Mouse Sequence

1979 • 256 citations

Isolation of the chicken β-globin gene and a linked embryonic β-like globin gene from a chicken DNA recombinant library

1979 • 243 citations

The primary sequence of rabbit α-globin mRNA

1978 • 174 citations

The structure and transcription of four linked rabbit β-like globin genes

1979 • 171 citations

Darwinian Evolution of Proteins

1970 • 163 citations

Molecular Evolution of Myoglobin and the Fossil Record: a Phylogenetic Synthesis

1973 • 155 citations

Is the evolution of insulin Darwinian or due to selectively neutral mutation?

1975 • 151 citations

Nucleotide sequence of a cDNA clone encoding human preproinsulin

1979 • 141 citations

SV40 recombinants carrying rabbit β-globin gene coding sequences

1979 • 139 citations

Non-Darwinian Evolution: A Critique

1970 • 137 citations

Differences in the nature of the interaction of insulin and proinsulin with zinc

1972 • 85 citations

Stochastic versus augmented maximum parsimony method for estimating superimposed mutations in the divergent evolution of protein sequences. Methods tested on cytochrome c amino acid sequences

1976 • 76 citations

Immunological and chemical characterization of bovine preproinsulin.

1977 • 60 citations

Interaction of zing with proinsulin

1970 • 59 citations

Primary Structures of the Proinsulin Connecting Peptides of the Rat and the Horse

1972 • 43 citations

Synthesis and properties of carbonylbis(methionyl)insulin, a proinsulin analog which is convertible to insulin by cyanogen bromide cleavage

1976 • 36 citations

Isolation and Amino‐Acid Sequence of the C‐Peptide of Duck Proinsulin

1973 • 13 citations