The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Experiments in molecular genetics

1972 • 28,260 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

A new method for sequencing DNA.

1977 • 7,941 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA

1972 • 2,842 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Genetic engineering. Principles and methods

1987 • 715 citations

Filamentous coliphage M13 as a cloning vehicle: insertion of a HindII fragment of the lac regulatory region in M13 replicative form in vitro.

1977 • 711 citations

The making of strand-specific M13 probes

1982 • 652 citations

Nucleotide sequence of the kanamycin resistance transposon Tn903

1981 • 577 citations

A bacterial clone synthesizing proinsulin.

1978 • 515 citations

Sequence of the gene for iso-l-cytochrome c in saccharomyces cerevisiae

1979 • 348 citations

Single-stranded DNA phages

1980 • 278 citations

A set of synthetic oligodeoxyribonucleotide primers for DNA sequencing in the plasmid vector pBR322

1981 • 260 citations

Methylation of single-stranded DNA in vitro introduces new restriction endonuclease cleavage sites

1978 • 246 citations

A versatile primer for DNA sequencing in the M13mp2 cloning system

1980 • 241 citations

Extracellular nucleases of Pseudomonas BAL 31. III. Use of the double-strand deoxyriboexonuclease activity as the basis of a convenient method for the mapping of fragments of DNA produced by cleavage with restriction enzymes

1978 • 234 citations

In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites.

1978 • 200 citations

Characterization of a mini-ColC1 plasmid

1976 • 196 citations

Nucleotide sequence of naturally occurring deletion mutants of cauliflower mosaic virus

1981 • 139 citations

Construction and properties of a new cloning vehicle, allowing direct sereening for recombinant plasmids

1980 • 117 citations

The use of exonuclease III for preparing single stranded DNA for use as a template in the chain terminator sequencing method

1979 • 101 citations

A method for sequencing single-stranded cloned DNA in both directions

1981 • 85 citations

The rapid purification of T4 DNA ligase from a lambda T4 lig lysogen.

1980 • 81 citations

[7] Synthetic adaptors for cloning DNA

1979 • 69 citations

Constructed Mutants Using Synthetic Oligodeoxyribonucleotides as Site-Specific Mutagens

1981 • 30 citations

A STRATEGY FOR HIGH-SPEED DNA SEQUENCING

1981 • 9 citations

The Filamentous Phage M13 as a Carrier DNA for Operon Fusions In Vitro

1978 • 7 citations