Glycoconjugates in autoimmunity

Cellular and Molecular Immunology

1994 • 3,469 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Cellular and Molecular Immunology

1992 • 2,768 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens

1985 • 1,184 citations

Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG

1985 • 1,136 citations

GLYCOBIOLOGY

1988 • 1,107 citations

Biological and clinical aspects of interleukin 6

1990 • 1,091 citations

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1993 • 1,087 citations

The Biochemistry and Cell Biology of Antigen Processing and Presentation

1993 • 1,022 citations

Ion motive ATPases. I. Ubiquity, properties, and significance to cell function

1987 • 964 citations

Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells.

1988 • 924 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Interleukin‐6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides

1988 • 859 citations

Dominance and Crypticity of T Cell Antigenic Determinants

1993 • 838 citations

Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis

1988 • 793 citations

Biology of Animal Lectins

1993 • 752 citations

T Cell-Dependent B Cell Activation

1993 • 727 citations

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

1991 • 694 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

The Role of the T Cell Receptor in Positive and Negative Selection of Developing T Cells

1990 • 589 citations

Origin of Murine B Cell Lineages

1993 • 579 citations

Transplantation of discordant xenografts: a review of progress

1990 • 538 citations

A bacterium lipopolysaccharide that elicits Guillain-Barré syndrome has a GM1 ganglioside-like structure.

1993 • 500 citations

Autoimmune Diseases: The Failure of Self Tolerance

1990 • 495 citations

Acquisition of immunologic self-tolerance

1989 • 484 citations

Collectins: collagenous C-type lectins of the innate immune defense system

1994 • 461 citations

Structure of sulfated glucuronyl glycolipids in the nervous system reacting with HNK-1 antibody and some IgM paraproteins in neuropathy.

1986 • 432 citations

Cytokine regulation of T-cell function: potential for therapeutic intervention

1993 • 412 citations

Diversity of Cytokine Synthesis and Function of Mouse CD4⁺ T Cells

1991 • 371 citations

Transgenic Mice and Analysis of B-Cell Tolerance

1992 • 362 citations

Blood group ABH and Ii antigens of human erythrocytes: chemistry, polymorphism, and their developmental change.

1981 • 344 citations

Self-Nonself Discrimination by T Cells

1990 • 331 citations

The CD5 B Cell

1989 • 327 citations

Characterization of sulfated glucuronic acid containing glycolipids reacting with IgM M-proteins in patients with neuropathy.

1987 • 315 citations

Autoantibodies against the platelet glycoprotein IIb/IIIa complex in patients with chronic ITP

1984 • 302 citations

Age-related galactosylation of the N-linked oligosaccharides of human serum IgG.

1988 • 290 citations

Development in the thymus: it takes two to tango

1993 • 281 citations

Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice

1992 • 281 citations

Characterization of a blood group I-active ganglioside. Structural requirements for I and i specificities.

1979 • 276 citations

Genetic susceptibility to post-thymectomy autoimmune diseases in mice

1981 • 265 citations

Campylobacter jejuni strains from patients with guillain‐barré syndrome belong mostly to penner serogrpup 19 and contain β‐N‐acetylglucosamine residues

1993 • 256 citations

Experimental demyelination of nerve induced by serum of patients with neuropathy and an anti‐MAG IgM M‐protein

1987 • 247 citations

The spectrum of neurologic disease associated with anti‐GM ₁ antibodies

1990 • 240 citations

T-Cell Differentiation is Influenced by Thymic Microenvironments

1991 • 239 citations

Major parietal cell antigen in autoimmune gastritis with pernicious anemia is the acid-producing H+,K+-adenosine triphosphatase of the stomach.

1988 • 227 citations

Peripheral T Cell Tolerance

1992 • 223 citations

GALACTOSYLATION OF IgG ASSOCIATED OLIGOSACCHARIDES: REDUCTION IN PATIENTS WITH ADULT AND JUVENILE ONSET RHEUMATOID ARTHRITIS AND RELATION TO DISEASE ACTIVITY

1988 • 221 citations

Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigens

1991 • 216 citations

Multiple levels of peripheral tolerance

1993 • 216 citations

Gangliosides GM1 and GD1b are antigens for IgM M-protein in a patientwith motor neuron disease

1986 • 208 citations

Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy

1991 • 206 citations

Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype.

1991 • 204 citations

Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells

1992 • 201 citations

Autoantibodies against platelet glycoprotein Ib in patients with chronic immune thrombocytopenic purpura

1984 • 200 citations

A comparative analysis of disease-associated changes in the galactosylation of serum IgG

1989 • 198 citations

The development and repertoire of B-1 cells (CD5 B cells)

1991 • 198 citations

Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells.

1992 • 197 citations

Experimental conduction block induced by serum from a patient with anti‐GM1 antibodies

1992 • 187 citations

Three types of blood group I specificity among monoclonal anti-I autoantibodies revealed by analogues of a branched erythrocyte glycolipid.

1979 • 183 citations

Monoclonal IgM with unique specificity to gangliosides GM ₁ and GD _1b and to lacto‐ N ‐tetraose associated with human motor neuron disease

1988 • 183 citations

Antigen-presenting cell types

1993 • 179 citations

The three-dimensional structure of the carbohydrate within the Fc fragment of immunoglobulin G.

1983 • 178 citations

Complement-Mediated Demyelination in Patients with IgM Monoclonal Gammopathy and Polyneuropathy

1990 • 177 citations

Subsets of CD4⁺ T Cells and their Roles in the Induction and Prevention of Autoimmunity

1991 • 174 citations

MHC molecules as peptide receptors

1993 • 169 citations

An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus.

1993 • 168 citations

Abnormal glycosylation of serum igg from patients with chronic inflammatory diseases

1988 • 167 citations

Cell biology of antigen presentation

1993 • 166 citations

Effects of galactose depletion from oligosaccharide chains on immunological activities of human IgG.

1989 • 162 citations

Pristane‐induced arthritis. the immunologic and genetic features of an experimental murine model of autoimmune disease

1989 • 156 citations

Synthesis and assembly of functional mammalian Na,K-ATPase in yeast.

1990 • 155 citations

The three-dimensional structure of the carbohydrate within the Fc fragment of immunoglobulin G

1983 • 150 citations

Expression of the developmental I antigen by a cloned human cDNA encoding a member of a beta-1,6-N-acetylglucosaminyltransferase gene family.

1993 • 144 citations

REDUCED B-CELL GALACTOSYLTRANSFERASE ACTIVITY IN RHEUMATOID ARTHRITIS

1987 • 141 citations

Autoimmune reactions to heat‐shock proteins in pristane‐induced arthritis

1990 • 140 citations

V_H4—21, A Human V_H Gene Segment Overrepresented in the Autoimmune Repertoire

1992 • 135 citations

Tolerance mechanism in experimental ovarian and gastric autoimmune diseases.

1992 • 134 citations

cDNA cloning of the beta-subunit of the rat gastric H,K-ATPase.

1990 • 134 citations

B-Cell neoplasms with homogeneous cold-reacting antibodies (cold agglutinins)

1982 • 133 citations

Demyelination induced by intraneural injection of human antimyelin‐associated glycoprotein antibodies

1988 • 131 citations

A protein structural change in aglycosylated IgG3 correlates with loss of huFcγR1 and hufcγR111 binding and/or activation

1990 • 128 citations

Self‐Ignorance in the Peripheral T‐Cell Pool

1993 • 124 citations

How αβ T-cell receptors ‘see’ peptide/MHC complexes

1993 • 124 citations

Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease.

1990 • 120 citations

IgM deposits at nodes of ranvier in a patient with amyotrophic lateral sclerosis, anti‐GM1 antibodies, and multifocal motor conduction block

1990 • 119 citations

Changes in normal glycosylation mechanisms in autoimmune rheumatic disease.

1992 • 117 citations

“Cytoplasmic” Islet Cell Antibodies: Evidence That the Target Antigen Is a Sialoglycoconjugate

1985 • 116 citations

The role of IgG glycoforms in the pathogenesis of rheumatoid arthritis

1988 • 115 citations

Experimental autoimmune neuropathy with anti-GM1 antibodies and immunoglobulin deposits at the nodes of Ranvier

1991 • 113 citations

Biosynthesis of blood group I antigens. Identification of a UDP-GlcNAc:GlcNAc beta 1-3Gal(-R) beta 1-6(GlcNAc to Gal) N-acetylglucosaminyltransferase in hog gastric mucosa.

1984 • 111 citations

Localization of GM1 and Gal(β1‐3)GalNAc antigenic determinants in peripheral nerve

1993 • 108 citations

Guillain-Barré syndrome associated with high titers of anti-GM1 antibodies

1992 • 104 citations

Selective differentiation of CD4+ T helper cell subsets

1993 • 104 citations

Peptide Binding to Major Histocompatibility Complex Molecules

1993 • 104 citations

The parietal cell autoantibodies recognized in neonatal thymectomy-induced murine gastritis are the α and β subunits of the gastric proton pump

1991 • 97 citations

Islet cell antigens in insulin-dependent diabetes: Pandora's box revisited

1992 • 97 citations

Cold Agglutination

1989 • 95 citations

Binding of Cytoplasmic Islet Cell Antibodies Is Blocked by Human Pancreatic Glycolipid Extracts

1988 • 93 citations

Predictive value of anti-GM1 ganglioside antibodies in neuromuscular diseases: a study of 180 sera

1991 • 92 citations

Sulfated glucuronyl glycolipids reacting with anti-myelin-associated glycoprotein monoclonal antibodies including IgM paraproteins in neuropathy: Species distribution and partial characterization of epitopes

1986 • 92 citations

Molecular targets in pernicious anaemia

1991 • 91 citations

Agalactosyl IgG: An aid to differential diagnosis in early synovitis

1991 • 90 citations

Sensory neuropathy associated with monoclonal immunoglobulin M to GD1b ganglioside

1992 • 89 citations

Isolation and characterization of gastric microsomal glycoproteins. evidence for a glycosylated β-subunit of the H+/K−-ATPase

1990 • 87 citations

N-glycosylation of HIV-gp120 may constrain recognition by T lymphocytes.

1991 • 83 citations

Role of the transmembrane and extracytoplasmic domain of beta subunits in subunit assembly, intracellular transport, and functional expression of Na,K-pumps.

1993 • 83 citations

Antigenic specificities of human monoclonal and polyclonal IgM rheumatoid factors. The C gamma 2-C gamma 3 interface region contains the major determinants.

1988 • 82 citations

Identification and Characterization of Gangliosides Reacting with IgM Paraproteins in Three Patients with Neuropathy Associated with Biclonal Gammopathy

1988 • 80 citations

Monosaccharide and oligosaccharide analysis of proteins transferred to polyvinylidene fluoride membranes after sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

1993 • 80 citations

Plasmapheresis alleviates neuropathy accompanying IgM anti—Myelin‐Associated glycoprotein paraproteinemia

1988 • 79 citations

Kinetic study of a galactosyltransferase in the B cells of patients with rheumatoid arthritis

1990 • 78 citations

Autoanti-red cell antibodies synthesized by patients with infectious mononucleosis utilize the VH4-21 gene segment.

1993 • 78 citations

Poly-N-acetyllactosamine-specific tomato lectin interacts with gastric parietal cells Identification of a tomato-lectin binding 60-90×103/Mr membrane glycoprotein of tubuloveslcles

1990 • 75 citations

Antibodies to sulfated glycolipids in Guillain-Barré syndrome

1991 • 75 citations

Assembly and Intracellular Transport of MHC Class I Molecules

1993 • 71 citations

Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases

1992 • 69 citations

The role of oil and agalactosyl IgG in the induction of arthritis in rodent models

1991 • 69 citations

Cytokines and Peripheral Tolerance to Alloantigen

1993 • 69 citations

Parietal cell antibodies in pernicious anemia inhibit H+, K+-adenosine triphosphatase, the proton pump of the stomach

1989 • 69 citations

Patterns of reactivity of human anti‐GM1 antibodies with spinal cord and motor neurons

1992 • 68 citations

Acute motor neuropathy with antibodies to GM1 ganglioside

1991 • 67 citations

Gastric parietal cell antigens of 60–90, 92, and 100–120 kDa associated with autoimmune gastritis and pernicious anemia

1989 • 65 citations

Ultrastructural localization of gastric parietal cell antigen with peroxidase-coupled antibody.

1970 • 64 citations

α and β Subunits of the Gastric H/K -ATPase Are Concordantly Targeted by Parietal Cell Autoantibodies Associated with Autoimmune Gastritis

1993 • 62 citations

"Cytoplasmic" islet cell antibodies. Evidence that the target antigen is a sialoglycoconjugate

1985 • 62 citations

Topology and affinity of T-cell receptor mediated recognition of peptide—MHC complexes

1993 • 57 citations

Variable gene usage, physiology and development of Ly-1+ (CD5+) B cells

1992 • 56 citations

An anti‐B cell autoantibody from Wiskott‐Aldrich syndrome which recognizes i blood group specificity on normal human B cells

1992 • 56 citations

Antibody specificity and immunoglobulin V_H utilization of human monoclonal CD5⁺ B cell lines

1991 • 56 citations

Development of αβ T cells

1993 • 56 citations

Function and pathology of the sugar chains of human immunoglobulin G

1990 • 52 citations

Transient expression of a p58 protein kinase cDNA enhances mammalian glycosyltransferase activity

1990 • 52 citations

A new human monoclonal cold agglutinin Sa recognizing terminal N- acetylneuraminyl groups on the cell surface

1980 • 50 citations

New perspectives on immunointervention in autoimmune diseases

1990 • 49 citations

B-cell tolerance

1992 • 49 citations

The mouse gastric H,K-ATPase beta subunit. Gene structure and co-ordinate expression with the alpha subunit during ontogeny.

1992 • 49 citations

Rapid purification of the gastric H+/K+-ATPase complex by tomato-lectin affinity chromatography

1992 • 47 citations

Rheumatoid arthritis: how well do the theories fit the evidence?

1993 • 47 citations

Antibodies against glycosphingolipids in sera of patients with idiopathic thrombocytopenic purpura

1987 • 45 citations

A monoclonal antibody raised by immunising mice with group A streptococci binds to agalactosyl IgG from rheumatoid arthritis.

1988 • 44 citations

Structure and specificities of anti-ganglioside autoantibodies associated with motor neuropathies.

1992 • 44 citations

Selective expression of a VHIV subfamily of immunoglobulin genes in human CD5+ B lymphocytes from cord blood.

1991 • 43 citations

Characterization of an epitope (determinant) structure in a developmentally regulated glycolipid antigen defined by a cold agglutinin Fl, recognition of α-sialosyl and α-l-fucosyl groups in a branched structure

1983 • 41 citations

Monoclonal IgM in two patients with motor neuron disease bind to the carbohydrate antigens Gal(β1–3)GalNAc and Gal(β1–3)GlcNAc

1988 • 41 citations

Binding of cytoplasmic islet cell antibodies is blocked by human pancreatic glycolipid extracts

1988 • 40 citations

Autoimmune Gastritis: Tolerance and Autoimmunity to the Gastric H⁺/K⁺Atpase (Proton Pump)

1992 • 39 citations

RELATIONSHIP BETWEEN INTERLEUKIN 6, AGALACTOSYL IgG AND PRISTANE-INDUCED ARTHRITIS

1992 • 39 citations

Agalactosyl IgG in pristane-induced arthritis. Pregnancy affects the incidence and severity of arthritis and the glycosylation status of IgG

1992 • 38 citations

Antibodies against platelet glycosphingolipids: detection in serum by quantitative HPTLC-autoradiography and association with autoimmune and alloimmune processes

1989 • 38 citations

.beta. Subunit of sodium-potassium ATPase contains three disulfide bonds

1990 • 37 citations

IgG galactosylation—Its biological significance and pathology

1991 • 36 citations

HLA-DP genotyping in patients with systemic lupus erythematosus: correlations with autoantibody subsets.

1992 • 36 citations

Human Monoclonal IgM Anti-Gal(β1-3)GaINAc Autoantibodies Bind to the Surface of Bovine Spinal Motoneurons

1990 • 35 citations

[22] Human monoclonal antibodies associated with neuropathy

1989 • 33 citations

Lymphocytes from patients with rheumatoid arthritis produce agalactosylated IgG in vitro

1992 • 33 citations

Antigen processing and presentation: close encounters in the endocytic pathway

1992 • 30 citations

Fucosyl‐GM1 in Human Sensory Nervous Tissue Is a Target Antigen in Patients with Autoimmune Neuropathies

1993 • 28 citations

Modulation of CD4+ T-Cell Recognition of Influenza Hemagglutinin by Carbohydrate Side Chains Located Outside a T-Cell Determinant

1993 • 25 citations

Monoclonal antibodies specific for the core protein of the β‐subunit of the gastric proton pump (H⁺/K⁺ ATPase)

1991 • 24 citations

Importance of the IgG isotype, not the state of glycosylation, in determining human rheumatoid factor binding

1990 • 23 citations

Identification of glycoconjugates which are targets for anti-Gal(β1-3)GalNAc autoantibodies in spinal motor neurons

1991 • 22 citations

CD5+ B-cell networks

1993 • 22 citations

Presentation of antigenic peptides by MHC class I molecules

1992 • 22 citations

Measurement and clinical importance of antibodies to glycosphingolipids

1990 • 20 citations

Gastritis

1990 • 20 citations

Human IgM monoclonal proteins that bind 3-fucosyllactosamine, asialo-GM1, and GM1.

1989 • 17 citations

Neolacto (Type‐2 Chain)‐Sialoautoantigens Recognized by Human Cold Agglutinins

1990 • 16 citations

Autoreactivity and CD5+ B cells

1990 • 15 citations

Diversity and the genesis of high affinity antibodies

1987 • 13 citations

Rheumatoid arthritis

1992 • 13 citations

Is there a Role for Mycobacteria in the Etiopathogenesis of Rheumatoid Arthritis?

1991 • 12 citations

Natural and pathologic human autoimmune responses to carbohydrate antigens on red blood cells

1993 • 9 citations

Taming Rogue Immune Reactions

1990 • 6 citations

S9.17 Structural studies on the glycosylation of the gastric H+, K+-ATpase

1993 • 2 citations