CREB as a Memory Modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in drosophila

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

1994 • 1,802 citations

Transposition of Cloned P Elements into Drosophila Germ Line Chromosomes

1982 • 1,560 citations

Protein synthesis and memory: A review.

1984 • 1,450 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

1991 • 1,300 citations

Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons

1993 • 1,212 citations

Classical conditioning and retention in normal and mutantDrosophila melanogaster

1985 • 1,170 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

1994 • 959 citations

Genetic dissection of consolidated memory in Drosophila

1994 • 901 citations

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

1993 • 817 citations

A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in Aplysia

1986 • 767 citations

Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation

1990 • 741 citations

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity.

1994 • 718 citations

Theories in Cognitive Psychology: The Loyola Symposium

1975 • 694 citations

CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

1991 • 655 citations

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

1994 • 612 citations

Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor

1993 • 592 citations

Loss of calcium/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant

1984 • 589 citations

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons

1993 • 549 citations

C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia

1994 • 528 citations

The Drosophila learning and memory gene rutabaga encodes a - adenylyl cyclase

1992 • 513 citations

Quantitative methods in psychology.

1960 • 502 citations

Developmental switch of CREM function during spermatogenesis: from antagonist to activator

1992 • 495 citations

Long-Term Sensitization of a Defensive Withdrawal Reflex in Aplysia

1973 • 493 citations

Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization.

1994 • 488 citations

Advances in second messenger and phosphoprotein research

1992 • 481 citations

MINIREVIEW: Cyclic AMP Response Element Binding Proteins: A Cornucopia of Transcription Factors

1990 • 394 citations

Neurobiology of comparative cognition

1991 • 388 citations

CREB: A mediator of long-term memory from mollusks to mammals

1994 • 371 citations

Theoretical Implications of the Spacing Effect 1

2024 • 368 citations

Activation of cAMP-Responsive genes by stimuli that produce long-term facilitation in aplysia sensory neurons

1993 • 353 citations

Heterodimer formation between CREB and JUN proteins.

1990 • 347 citations

Monosynaptic connections made by the sensory neurons of the gill- and siphon-withdrawal reflex in Aplysia participate in the storage of long-term memory for sensitization

1985 • 334 citations

Preferential expression in mushroom bodies of the catalytic subunit of protein kinase A and its role in learning and memory

1993 • 302 citations

Neural and Behavioural Plasticity

1991 • 300 citations

Long-Term Habituation of a Defensive Withdrawal Reflex in Aplysia

1972 • 286 citations

Neurobiology of Comparative Cognition

2014 • 284 citations

A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression.

1994 • 278 citations

Pituitary hormone FSH directs the CREM functional switch during spermatogenesis

1993 • 267 citations

Memory: Organization and Locus of Change

1992 • 267 citations

Flavor-Illness Aversions: the Peculiar Roles of Odor and Taste in Memory for Poison

1980 • 265 citations

Inhibitor of protein synthesis blocks longterm behavioral sensitization in the isolated gill‐withdrawal reflex of Aplysia

1989 • 240 citations

The functional versatility of CREM is determined by its modular structure.

1993 • 226 citations

Uber das Gedachtnis

1996 • 207 citations

cAMP-dependent protein kinase and the disruption of learning in transgenic flies

1991 • 181 citations

Vectors: a survey of molecular cloning vectors and their uses.

1988 • 173 citations

Thiophosphorylation of U1-70K protein inhibits pre-mRNA splicing

1993 • 152 citations

Different binding specificities and transactivation of variant CRE's by CREB complexes

1994 • 144 citations

Structural correlates of information storage in the mammalian brain: a review and hypothesis

1984 • 139 citations

latheo, a new gene involved in associative learning and memory in Drosophila melanogaster, identified from P element mutagenesis.

1992 • 136 citations

IDENTIFICATION OFLINOTTE, A NEW GENE AFFECTING LEARNING AND MEMORY INDROSOPHILA MELANOGASTER

2007 • 136 citations

Alternative usage of initiation codons in mRNA encoding the cAMP-responsive-element modulator generates regulators with opposite functions.

1992 • 131 citations

Transsynaptic Control of Gene Expression

1993 • 124 citations

Identification ofLinotte, a New Gene Affecting Learning and Memory inDrosophila Melanogaster

1993 • 116 citations

The promoter of the gene encoding 3',5'-cyclic adenosine monophosphate (cAMP) response element binding protein contains cAMP response elements: evidence for positive autoregulation of gene transcription.

1993 • 104 citations

Hormonal control of gene expression: multiplicity and versatility of cyclic adenosine 3',5'-monophosphate-responsive nuclear regulators.

1993 • 103 citations

An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription.

1994 • 86 citations

Long-Term Synaptic Changes Produced by a Cellular Analog of Classical Conditioning in Aplysia

1990 • 76 citations

Genetic dissection of the learning/memory gene dunce of Drosophila melanogaster.

1993 • 76 citations

cAMP induces long-term morphological changes in sensory neurons ofAplysia

1991 • 75 citations

Retrograde amnesia in honeybees ( Apis mellifera carnica ).

1976 • 48 citations

Changes in dendritic and synaptic structure in chick forebrain consequent on passive avoidance learning

1991 • 43 citations

Tracking the flow of learned information from membrane receptors to genome

1986 • 40 citations

Differential Effects ofDunceMutations on Associative Learning and Memory inDrosophila

1993 • 33 citations

Effect of cycloheximide on protein synthesis and memory in praying mantis

1980 • 27 citations

Structural changes underlying long-term memory storage in Aplysia: a molecular perspective

1994 • 20 citations