The microcirculation during endotoxemia

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

1992 • 1,635 citations

The Pathogenesis of Sepsis

1991 • 1,376 citations

BIOCHEMISTRY OF ENDOTOXINS

1990 • 1,201 citations

Adhesion molecules and inflammatory injury

1994 • 1,023 citations

Biologically active products of stimulated liver macrophages (Kupffer cells)

1990 • 926 citations

The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion

1994 • 863 citations

Antibiotics prevent liver injury in rats following long-term exposure to ethanol

1995 • 698 citations

The effects of bacterial endotoxins on host mediation systems. A review.

1978 • 648 citations

Nitrogen Oxide Levels in Patients After Trauma and During Sepsis

1991 • 609 citations

Inactivation of Kupffer cells prevents early alcohol-induced liver injury

1994 • 550 citations

The coronary circulation in human septic shock.

1986 • 466 citations

Stress Proteins and Immunology

1990 • 458 citations

The Clearance, Tissue Distribution, and Cellular Localization of Intravenously Injected Lipopolysaccharide in Rabbits

1979 • 427 citations

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.

1989 • 405 citations

Pathogenesis of Disseminated Intravascular Coagulation in Sepsis

1993 • 349 citations

Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia

1992 • 327 citations

Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion?

1992 • 323 citations

Alterations in nitric oxide production in various forms of circulatory shock.

1995 • 321 citations

Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2.

1993 • 289 citations

Bacterial Endotoxic Lipopolysaccharides

2024 • 267 citations

Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia

1993 • 252 citations

Acute effects of Escherichia coli endotoxin on the pulmonary microcirculation of anesthetized sheep structure:function relationships.

1983 • 245 citations

Protective effects of hsp70 in inflammation

1994 • 241 citations

Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection.

1993 • 223 citations

Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats

1992 • 213 citations

Endotoxin-induced cytokine gene expression and excretion in the liver

1994 • 213 citations

Intestinal endotoxins as mediators of hepatic injury—An idea whose time has come again

1989 • 208 citations

Endotoxin, septic shock and acute lung injury: Neutrophils, macrophages and inflammatory mediators

1992 • 195 citations

Uptake by liver cells of endotoxin following its intravenous injection.

1981 • 187 citations

Bacterial heat shock proteins directly induce cytokine mRNA and interleukin-1 secretion in macrophage cultures

1994 • 166 citations

Recognition of Bacterial Endotoxins by Receptor-Dependent Mechanisms

1993 • 159 citations

Mediators of septic shock

1993 • 156 citations

Complement and tumor necrosis factor-α contribute to Mac-1 (CD11b/CD18) up-regulation and systemic neutrophil activation during endotoxemia in vivo

1994 • 143 citations

Myocardial and circulatory effects of E. coli endotoxin; modification of responses to catecholamines

1973 • 135 citations

Relationship between tumor necrosis factor-alpha and neutrophils in endotoxin-induced liver injury

1993 • 128 citations

Tumor Necrosis Factor in Alcohol Enhanced Endotoxin Liver Injury

1992 • 127 citations

The nonspecific nature of endotoxin tolerance

1995 • 126 citations

Inhibition of Nitric Oxide Synthesis Causes Myocardial Ischemia in Endotoxemic Rats

1995 • 122 citations

Endotoxin, interleukin-1, and tumor necrosis factor cause neutrophil-dependent microvascular leakage in postcapillary venules.

1992 • 102 citations

The role of tumor necrosis factor-α in acute endotoxin-induced hepatotoxicity in ethanol-fed rats

1994 • 102 citations

Common pathway of endothelial-leukocyte interaction in shock, ischemia, and reperfusion

1993 • 99 citations

INCREASED NITRIC OXIDE SYNTHESIS DURING THE DEVELOPMENT OF ENDOTOXIN TOLERANCE

1995 • 77 citations

Kupffer Cell Function in Host Defense

1987 • 66 citations

Pathogenesis of disseminated intravascular coagulation in sepsis

1993 • 63 citations

Species differences in Kupffer cells and endotoxin sensitivity

1984 • 63 citations

Induction of Endotoxin Tolerance

1983 • 60 citations

Fine structure of hepatic sinusoids and sinusoidal cells in disease

1990 • 57 citations

The effect of endotoxin and tumour necrosis factor on erythrocyte and leucocyte deformability in vitro

1993 • 55 citations

VALUE OF SUPEROXIDE DISMUTASE FOR PREVENTION OF MULTIPLE ORGAN FAILURE AFTER MULTIPLE TRAUMA

1993 • 55 citations

Microvascular responses to E. coli endotoxin with altered adrenergic activity.

1984 • 53 citations

Macrophage Endotoxin Tolerance: Effect of TNF or Endotoxin Pretreatment

1994 • 53 citations

Inactivation of Kupffer cells prevents early alcohol-induced liver injury

1994 • 49 citations

Non-enzymic activation of the fifth component of human complement, by oxygen radicals. Some properties of the activation product, C5b-like C5

1989 • 48 citations

von Willebrand factor release induced by endotoxin.

1989 • 46 citations

Polymorphonuclear neutrophil contribution to induced tolerance to bacterial lipopolysaccharide.

1991 • 45 citations

In vivo production of heat shock protein in mouse peritoneal macrophages by administration of lipopolysaccharide

1994 • 44 citations

In vivo microscopic studies of the responses of the liver to endotoxin

1982 • 44 citations

Role of endotoxin in the hepatic microvascular inflammatory response to ethanol

1995 • 43 citations

Activation of human endothelial cells by viable or heat-killed gram-negative bacteria requires soluble CD14

1995 • 43 citations

Maurice Landy and Werner Braun (Herausgeber), Bacterial Endotoxins. 691 S. 116 Abb., 201 Tab., New Brunswick, N. J. 1964: Institute of Microbiology, Rutgers, The State University. $ 12.—

1965 • 42 citations

In vivo microscopic observations of the responses of Kupffer cells and the hepatic microcirculation to Mycobacterium bovis BCG alone and in combination with endotoxin

1983 • 42 citations

Tumor Necrosis Factor and Interleukin 1 as Mediators of Endotoxin-Induced Beneficial Effects

1987 • 42 citations

The anti mac-1 monoclonal antibody inhibits neutrophil sequestration in lung and liver in a septic murine model

1991 • 41 citations

EFFECTS OF CYTOKINES TUMOR NECROSIS FACTOR α AND INTERLEUKIN 1β ON ENDOTOXIN-MEDIATED INHIBITION OF ENDOTHELIUM-DERIVED RELAXING FACTOR BIOACTIVITY AND NITRIC OXIDE PRODUCTION IN VASCULAR ENDOTHELIUM

1994 • 40 citations

In Vivo And Electron Microscopic Observations of the Hepatic Micro Vasculature in the Rat Following Portacaval Anastomosis

1983 • 40 citations

The role of pentoxifylline in endotoxin-induced alterations of red cell deformability and whole blood viscosity in the neonate

1991 • 38 citations

Endotoxin, sinusoidal cells, and liver injury.

1982 • 38 citations

Gram-Negative Bacterial Infections and Mode of Endotoxin Actions

1975 • 38 citations

Effects of<scp>d</scp>-Galactosamine-induced Acute Liver Injury on Mortality and Pulmonary Responses toEscherichia coliLipopolysaccharide: Modulation by Arachidonic Acid Metabolites

1990 • 36 citations

ROLE OF NITRIC OXIDE IN THE SMALL INTESTINAL MICROCIRCULATION DURING BACTEREMIA

1994 • 34 citations

Role of leukocytes in the initial hepatic microvascular response to endotoxemia.

1993 • 32 citations

Stress Proteins And Immunology

1990 • 31 citations

Arteriolar endothelium-dependent vasodilation occurs during endotoxin shock

1993 • 31 citations

Protective effects and role of endotoxin in experimental septicemia.

1984 • 31 citations

Attenuation of endotoxin-induced intestinal microcirculatory damage by eicosapentanoic acid

1993 • 30 citations

Endotoxin-induced procoagulant activity, eicosanoid synthesis, and tumor necrosis factor production by rat peritoneal macrophages: effect of endotoxin tolerance and glucan.

1990 • 29 citations

Involvement of bradykinin and nitric oxide in the early hemodynamic effects of lipopolysaccharide in rats.

1995 • 28 citations

Increase of the Effect of Histamine by E. coli Endotoxin on the Smooth Muscle

1965 • 26 citations

Oxyradical Generation from Leukocytes during Endotoxin-Induced Microcirculatory Disturbance in Rat Mesentery-Attenuating Effect of Cetraxate

1993 • 23 citations

PAF-acether and endotoxin display similar effects on rat mesenteric microvessels: inhibition by specific antagonists.

1988 • 21 citations

Intrinsic myocardial dysfunction during endotoxemia: dependent or independent of myocardial ischemia?

1990 • 19 citations

Deficient Kupffer Cell Phagocytosis and Lysosomal Enzymes in the Endotoxin-Low- Responsive C3H/HeJ Mouse

1984 • 19 citations

Role of neutrophils in endotoxin-mediated microvascular injury in hamsters

1991 • 19 citations

The inflammatory response to endotoxins.

1979 • 17 citations

INHIBITION OF ENDOTOXIN-INDUCED MICROVASCULAR LEAKAGE BY A PLATELET-ACTIVATING FACTOR ANTAGONIST AND 5-LIPOXYGENASE INHIBITOR

1995 • 16 citations

Hepatic microvascular regulatory mechanisms. III. Aminergic mechanisms as related to mast cells.

1983 • 16 citations

EFFECTS OF NW-NITRO-L-ARGININE AND DEXAMETHASONE ON EARLY EVENTS FOLLOWING LIPOPOLYSACCHARIDE INJECTION

1994 • 16 citations

Endotoxin-induced increase in leukocyte adherence and macromolecular permeability of postcapillary venules

1990 • 16 citations

Eicosanoid profile and evidence for endotoxin tolerance in chronic ethanol-fed rats

1994 • 15 citations

Aspects of beneficial endotoxin-mediated effects

1982 • 15 citations

Role of eicosanoids in experimental alcoholic liver disease

1993 • 14 citations

Lack of endotoxin effect on the microcirculation after pretreatment with detoxified endotoxin (endotoxoid)

1968 • 12 citations

Reduced microvascular adrenergic receptor activity due to opioids in endotoxin shock.

1990 • 10 citations

Hepatic Responses to Bacterial Endotoxin (LPS)

1993 • 10 citations

Uncoupling of coronary microvascular beta 2-adrenoceptors by Escherichia coli endotoxemia.

1994 • 9 citations

Erste Beobachtungen mit dem Rasterelektronenmikroskop in der Fr�hphase der Endotoxinwirkung an der terminalen Strombahn

1969 • 8 citations

The effect of endotoxin on the neonatal erythrocyte

1993 • 7 citations

Pathophysiology of Shock, Sepsis, and Organ Failure

1995 • 6 citations

The Role of Post-Endotoxin Serum Components from BCG Infected Mice in the Protection of Compromised Hosts

1986 • 5 citations

Endotoxin-Induced Microcirculatory Disturbances

1976 • 4 citations

Hepatic microvascular regulatory mechanisms. VII. Effects of endoportally-infused endotoxin on microcirculation and mast cells in rats.

1986 • 4 citations

Modification of vasopressin microvascular responses by endotoxin, endothelin, and nitric oxide.

1994 • 4 citations

Hepatic microvascular regulatory mechanisms. VI. Effects of lodoxamide tromethamine or phentolamine-HCl on early hemodynamic and glucoregulatory alterations evoked by endotoxin.

1985 • 3 citations

The effect of endotoxin on neonatal erythrocyte intracellular calcium concentration

1994 • 3 citations

Hepatic microvascular regulatory mechanisms. IX. Effects of compound 48/80 on endotoxin-induced changes in microcirculation and mast cell integrity.

1986 • 2 citations

Endotoxins and microvascular functions

2016 • 1 citations

Emigration of activated leukocytes augments transvascular permeability in mesenteric venules of rat.

1991 • 1 citations