Adhesion molecules and inflammatory injury

Nitric oxide: an endogenous modulator of leukocyte adhesion.

1991 • 3,079 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Selectins: Interpreters of Cell-Specific Carbohydrate Information During Inflammation

1992 • 1,255 citations

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

PECAM-1 is required for transendothelial migration of leukocytes.

1993 • 1,134 citations

Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro.

1989 • 1,115 citations

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

1993 • 1,058 citations

Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo.

1991 • 977 citations

Regulation of Rransendothelial Neutrophil Migration by Endogenous Interleukin-8

1991 • 813 citations

THE ROLE OF ENDOTHELIAL CELLS IN INFLAMMATION

1990 • 808 citations

Endothelial cell interactions with granulocytes: tethering and signaling molecules

1992 • 773 citations

Expression cloning of a functional glycoprotein ligand for P-selectin

1993 • 734 citations

Physiological and Molecular Mechanisms of Lymphocyte Homing

1992 • 655 citations

The Severe and Moderate Phenotypes of Heritable Mac-1, LFA-1 Deficiency: Their Quantitative Definition and Relation to Leukocyte Dysfunction and Clinical Features

1985 • 644 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140

1991 • 592 citations

Recurrent Severe Infections Caused by a Novel Leukocyte Adhesion Deficiency

1992 • 555 citations

Divalent cation regulation of the function of the leukocyte integrin LFA-1.

1992 • 492 citations

Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigration

1992 • 477 citations

Involvement of Platelet-Endothelial Cell Adhesion Molecule-1 in Neutrophil Recruitment in Vivo

1993 • 468 citations

Endothelial Interleukin-8: A Novel Inhibitor of Leukocyte-Endothelial Interactions

1989 • 459 citations

In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

1993 • 452 citations

Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies.

1986 • 423 citations

CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits.

1990 • 423 citations

Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1.

1989 • 413 citations

Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats.

1991 • 398 citations

Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140).

1992 • 385 citations

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

1992 • 383 citations

Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors.

1992 • 361 citations

Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells.

1993 • 340 citations

A PHASE I TRIAL OF IMMUNOSUPPRESSION WITH ANTIIC AM-1 (CD54) mAb IN RENAL ALLOGRAFT RECIPIENTS

1993 • 299 citations

Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor–IgG chimaera

1991 • 293 citations

E-selectin supports neutrophil rolling in vitro under conditions of flow.

1993 • 273 citations

Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140

1990 • 257 citations

Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides.

1994 • 250 citations

Gene targeting yields a CD18-mutant mouse for study of inflammation.

1993 • 240 citations

L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo

1992 • 239 citations

Selectin-mediated rolling of neutrophils on immobilized platelets

1993 • 236 citations

Endothelial leukocyte adhesion molecule-1 mediates antigen-induced acute airway inflammation and late-phase airway obstruction in monkeys.

1991 • 233 citations

Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers.

1993 • 213 citations

Requirements for leukocyte adhesion molecules in nephrotoxic nephritis.

1993 • 197 citations

Endothelial adhesion molecules and their role in inflammation

1993 • 180 citations

Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans

1993 • 180 citations

Dapsone Suppresses Integrin-Mediated Neutrophil Adherence Function

1992 • 163 citations

Roles of beta 2 integrins of rat neutrophils in complement- and oxygen radical-mediated acute inflammatory injury.

1992 • 153 citations

Role of beta 1, beta 2 integrins and ICAM-1 in lung injury after deposition of IgG and IgA immune complexes.

1993 • 149 citations

Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear.

1993 • 149 citations

In vitro inhibitory effect of IL-8 and other chemoattractants on neutrophil-endothelial adhesive interactions.

1992 • 141 citations

Expression and functional characterization of a soluble form of endothelial-leukocyte adhesion molecule 1.

1991 • 141 citations

Protective effects of selectin chimeras in neutrophil-mediated lung injury.

1993 • 122 citations

Role of leukocyte adhesion molecules in complement-induced lung injury.

1993 • 115 citations

N-(fluorenyl-9-methoxycarbonyl) amino acids, a class of antiinflammatory agents with a different mechanism of action.

1991 • 110 citations

Human/severe combined immunodeficient mouse chimeras. An experimental in vivo model system to study the regulation of human endothelial cell-leukocyte adhesion molecules.

1993 • 103 citations

Platelet Endothelial Cell Adhesion Molecule (CD31)

1993 • 90 citations

Neutrophil recognition requires a Ca(2+)-induced conformational change in the lectin domain of GMP-140.

1991 • 70 citations

Polymorphonuclear leukocyte – endothelium interactions: a role for pro-inflammatory and anti-inflammatory molecules

1993 • 65 citations

Leukotriene B4-induced neutrophil-mediated endothelial leakage in vitro and in vivo

1991 • 58 citations

Inhibition of Molt-4-endothelial adherence by synthetic peptides from the sequence of ICAM-1.

1992 • 46 citations

Inhibition of intercellular adhesion molecule 1-dependent biological activities by a synthetic peptide analog.

1991 • 31 citations

Mechanisms of Neutrophil Migration across Endothelium

1992 • 22 citations

Endothelial Cell Binding of NAP-1/IL-8: Role in Neutrophil Emigration

1993 • 19 citations

Specificity and Regulation of CD18-Dependent Adhesions

1990 • 12 citations

The Role of LFA-1 and Related Antigens in Adhesion-Mediated Functions of Human Monocytes

1990 • 2 citations