Tumor Necrosis Factor in Alcohol Enhanced Endotoxin Liver Injury

Cachectin: More Than a Tumor Necrosis Factor

1987 • 1,457 citations

Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.

1987 • 1,345 citations

Galactosamine-induced sensitization to the lethal effects of endotoxin.

1979 • 940 citations

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

1990 • 828 citations

Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients

1991 • 543 citations

Increased tumor necrosis factor production by monocytes in alcoholic hepatitis

1989 • 542 citations

Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess

1987 • 539 citations

Methylprednisolone Therapy in Patients with Severe Alcoholic Hepatitis

1989 • 487 citations

Increased Plasma Tumor Necrosis Factor in Severe Alcoholic Hepatitis

1990 • 470 citations

Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral venous blood in patients with cirrhosis

1988 • 430 citations

Colchicine in the Treatment of Cirrhosis of the Liver

1988 • 327 citations

Plasma Tumor Necrosis Factor α Predicts Decreased Long‐Term Survival in Severe Alcoholic Hepatitis

1990 • 305 citations

Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice

1989 • 304 citations

Ethanol-induced liver fibrosis in rats fed high fat diet

1986 • 279 citations

Acute in vivo effects of human recombinant tumor necrosis factor.

1987 • 256 citations

The Effects of Acute and Chronic Alcoholism on Tumor Necrosis Factor and the Inflammatory Response

1989 • 239 citations

Intestinal endotoxins as mediators of hepatic injury—An idea whose time has come again

1989 • 208 citations

Serum-free in vitro bioassay for the detection of tumor necrosis factor

1986 • 195 citations

Endotoxin induced hepatic necrosis in rats on an alcohol diet

1987 • 172 citations

Biochemical and clinical response of fulminant viral hepatitis to administration of prostaglandin E. A preliminary report.

1989 • 162 citations

Involvement of tumor necrosis factor-α in development of hepatic injury in galactosamine-sensitized mice

1990 • 159 citations

Endotoxemia, encephalopathy, and mortality in cirrhotic patients.

1987 • 146 citations

The protective effects of prostaglandin E1 in an experimental massive hepatic cell necrosis model

1987 • 142 citations

Involvement of tumor necrosis factor-α in the pathogenesis of activated macrophage-mediated hepatitis in mice

1990 • 128 citations

Acute Alcohol Infusion Suppresses Endotoxin‐induced Serum Tumor Necrosis Factor

1989 • 117 citations

Cytokines and inflammation

1992 • 101 citations

Abnormal polyunsaturated fatty acid patterns of serum lipids in alcoholism and cirrhosis: arachidonic acid deficiency in cirrhosis.

1985 • 79 citations

Quantitative studies of ferritinlike iron in erythrocytes of thalassemia, sickle-cell anemia, and hemoglobin Hammersmith with Mössbauer spectroscopy.

1979 • 70 citations

Endotoxin-induced hypercoagulability: A possible aggravating factor of alcoholic liver disease

1989 • 55 citations

Endotoxin and the Liver. I. Toxicity in Rats with Choline Deficient Fatty Livers

1968 • 51 citations

Experimental Shigella Infections. III. Sensitivity of Normal, Starved and Carbon Tetrachloride Treated Guinea Pigs to Endotoxin

1960 • 48 citations

Prostaglandin E2 and leukotriene B4 synthesis by peripheral leucocytes in alcoholics.

1989 • 26 citations

Endotoxin-induced hyperinsulinemia and hyperglucagonemia after experimental liver injury

1981 • 19 citations