The HIV-1 coat protein gp120 regulates cxcr4-mediated signaling in neural progenitor cells

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

2003 • 4,175 citations

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Pathways to neuronal injury and apoptosis in HIV-associated dementia

2001 • 1,190 citations

CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity

2001 • 1,024 citations

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

1998 • 697 citations

Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

1999 • 513 citations

The chemokine SDF‐lα triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway

1999 • 510 citations

β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

2003 • 497 citations

CXCR4 Regulates Interneuron Migration in the Developing Neocortex

2003 • 441 citations

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

2002 • 413 citations

The chemokine SDF1 regulates migration of dentate granule cells

2002 • 383 citations

A Dual Role for the SDF-1/CXCR4 Chemokine Receptor System in Adult Brain: Isoform-Selective Regulation of SDF-1 Expression Modulates CXCR4-Dependent Neuronal Plasticity and Cerebral Leukocyte Recruitment after Focal Ischemia

2002 • 372 citations

Neurogenesis after ischaemic brain insults

2003 • 370 citations

Chemokine receptors: signposts to brain development and disease

2003 • 292 citations

SDF-1α induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells

2001 • 292 citations

A Point Mutation That Confers Constitutive Activity to CXCR4 Reveals That T140 Is an Inverse Agonist and That AMD3100 and ALX40-4C Are Weak Partial Agonists

2002 • 246 citations

Chemotaxis of macrophages is abolished in the Wiskott‐Aldrich syndrome

1998 • 241 citations

The Chemokine Stromal Cell-Derived Factor-1 Regulates the Migration of Sensory Neuron Progenitors

2005 • 216 citations

Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells

2004 • 216 citations

Chemokines Promote Quiescence and Survival of Human Neural Progenitor Cells

2004 • 163 citations

Differential signalling of the chemokine receptor CXCR4 by stromal cell‐derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes

2000 • 159 citations

Stromal cell‐derived factor 1‐mediated CXCR4 signaling in rat and human cortical neural progenitor cells

2004 • 152 citations

Antigenically Distinct Conformations of CXCR4

2001 • 151 citations

Protean agonism at histamine H ₃ receptors in vitro and in vivo

2003 • 145 citations

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways

2003 • 144 citations

Encephalopathy and progression of human immunodeficiency virus disease in a cohort of children with perinatally acquired human immunodeficiency virus infection

1998 • 125 citations

HIV‐1 Promotes Quiescence in Human Neural Progenitor Cells

2004 • 120 citations

Expression of chemokine receptors CXCR4, CCR2, CCR5 and CX3CR1 in neural progenitor cells isolated from the subventricular zone of the adult rat brain

2004 • 110 citations

JNK and p38 MAP kinases in CD4⁺ and CD8⁺ T cells

2003 • 100 citations

Regulation of CXCR4 Receptor Dimerization by the Chemokine SDF-1α and the HIV-1 Coat Protein gp120: A Fluorescence Resonance Energy Transfer (FRET) Study

2004 • 94 citations

High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells

2004 • 77 citations

Exploitation of Cellular Signaling by HIV-1: Unwelcome Guests with Master Keys That Signal Their Entry

2000 • 75 citations

Impaired Spatial Cognition and Synaptic Potentiation in a Murine Model of Human Immunodeficiency Virus Type 1 Encephalitis

2002 • 74 citations

Recent developments in the HIV neuropathies

2003 • 65 citations

Phosphorylation and Regulation of Psychostimulant-Sensitive Neurotransmitter Transporters

2004 • 61 citations

Neuropathogenesis of central nervous system HIV-1 infection

2002 • 58 citations

Soluble Fractalkine Prevents Monocyte Chemoattractant Protein-1-Induced Monocyte Migration via Inhibition of Stress-Activated Protein Kinase 2/p38 and Matrix Metalloproteinase Activities

2004 • 55 citations

Recent developments in the HIV neuropathies

2003 • 49 citations

Exploitation of the HIV‐1 coat glycoprotein, gp120, in neurodegenerative studies in vivo

2001 • 41 citations

Cognitive Decline With Immunologic and Virologic Stability in Four Children With Human Immunodeficiency Virus Disease

2003 • 39 citations

CD4 dependence of gp120IIIB-CXCR4 interaction is cell-type specific

2003 • 21 citations

Selected Models of HIV-Induced Neurological Disease

1995 • 19 citations

Chemokine Receptors, Neural Progenitor Cells, and the AIDS Dementia Complex

2004 • 13 citations