Impaired Spatial Cognition and Synaptic Potentiation in a Murine Model of Human Immunodeficiency Virus Type 1 Encephalitis

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Developments of a water-maze procedure for studying spatial learning in the rat

1984 • 6,896 citations

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice

1999 • 918 citations

Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta.

1993 • 789 citations

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes.

1988 • 785 citations

Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus‐type 1 (HIV‐1) infection

1991 • 755 citations

Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

1997 • 631 citations

Impaired Hippocampal Representation of Space in CA1-Specific NMDAR1 Knockout Mice

1996 • 594 citations

Changes to AIDS dementia complex in the era of highly active antiretroviral therapy

1999 • 422 citations

Abnormal Synaptic Plasticity and Impaired Spatial Cognition in Mice Transgenic for Exon 1 of the Human Huntington's Disease Mutation

2000 • 406 citations

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

1997 • 331 citations

Changes in pathological findings at autopsy in AIDS cases for the last 15 years

2000 • 327 citations

Clinical‐neuropathologic correlation in HIV‐associated dementia

1993 • 325 citations

Slow, persistent replication of lentiviruses: role of tissue macrophages and macrophage precursors in bone marrow.

1985 • 320 citations

Reduced basal ganglia volume in HIV‐1‐associated dementia

1993 • 318 citations

Incidence and prevalence of neurological disorders associated with HIV since the introduction of highly active antiretroviral therapy (HAART)

2000 • 309 citations

Biology and Pathogenesis of Lentiviruses

1989 • 281 citations

Microglial and Astrocyte Chemokines Regulate Monocyte Migration through the Blood-Brain Barrier in Human Immunodeficiency Virus-1 Encephalitis

1999 • 278 citations

Impaired Synaptic Plasticity and cAMP Response Element-Binding Protein Activation in Ca²⁺/Calmodulin-Dependent Protein Kinase Type IV/Gr-Deficient Mice

2000 • 251 citations

Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice

2000 • 245 citations

Reactive Gliosis as a Consequence of Interleukin-6 Expression in the Brain: Studies in Transgenic Mice

1994 • 242 citations

Interleukin-6 (IL-6) Production by Astrocytes: Autocrine Regulation by IL-6 and the Soluble IL-6 Receptor

1999 • 229 citations

Drawing Abilities in Williams Syndrome: A Case Study

2000 • 223 citations

Selective Neuronal Vulnerability in HIV Encephalitis

1992 • 216 citations

THE NEUROPATHOLOGY OF THE ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS)

1988 • 209 citations

Cortical dendritic pathology in human immunodeficiency virus encephalitis.

1992 • 194 citations

Early viral replication in the brain of SIV-infected rhesus monkeys.

1991 • 184 citations

Pro-inflammatory cytokines induce the transcription factors C/EBP? and C/EBP? in astrocytes

2000 • 181 citations

Suppression of Inflammatory Neurotoxins by Highly Active Antiretroviral Therapy in Human Immunodeficiency Virus‐Associated Dementia

1998 • 162 citations

Human immunodeficiency virus encephalitis in SCID mice.

1996 • 161 citations

Deficits in memory and hippocampal long-term potentiation in mice with reduced calbindin D28K expression.

1996 • 158 citations

Magnetic resonance imaging measurement of gray matter volume reductions in HIV dementia

1995 • 145 citations

Enhanced HIV replication in macrophage colony-stimulating factor-treated monocytes.

1991 • 143 citations

Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages

2001 • 135 citations

Cascading Glia Reactions: a Common Pathomechanism and Its Differentiated Control by Cyclic Nucleotide Signaling

2000 • 129 citations

Magnetic Resonance Imaging Morphometric Analysis of Cerebral Volume Loss in Human Immunodeficiency Virus Infection

1993 • 126 citations

An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis

1997 • 124 citations

Human immunodeficiency virus type 1 (HIV-1) infection of the nervous system: a review.

1988 • 109 citations

Encephalitis caused by human immunodeficiency virus: CT and MR imaging manifestations with clinical and pathologic correlation.

1990 • 95 citations

A hypothermic miniaturized stereotaxic instrument for surgery in newborn rats

1993 • 95 citations

Impaired learning and memory and altered hippocampal neurodevelopment resulting from interleukin-2 gene deletion

1999 • 83 citations

Advanced Glycation Endproducts in Neurofilament Conglomeration of Motoneurons in Familial and Sporadic Amyotrophic Lateral Sclerosis

1998 • 82 citations

Brain-IL-1β induces local inflammation but systemic anti-inflammatory response through stimulation of both hypothalamic–pituitary–adrenal axis and sympathetic nervous system

1999 • 63 citations

Spatial learning impairment in a murine model of AIDS

1992 • 61 citations

Covalent Crosslinking of Neurofilament Proteins by Oxidized Catechols as a Potential Mechanism of Lewy Body Formation

1995 • 59 citations

1H MR spectroscopy of the brain in HIV-1-seropositive subjects: evidence for diffuse metabolic abnormalities.

1998 • 58 citations

Development of laboratory and animal model systems for HIV-1 encephalitis and its associated dementia

1997 • 56 citations

Intact LTP and Fear Memory but Impaired Spatial Memory in Mice Lacking Cav2.3 (αIE) Channel

2001 • 52 citations

Lentivirus infection of macrophages.

1994 • 38 citations

Characterization of Carbon Disulfide Neurotoxicity in C57BL6 Mice: Behavioral, Morphologic, and Molecular Effects

2000 • 37 citations

The development of animal model systems for HIV-1 encephalitis and its associated dementia

1995 • 35 citations

Brain-derived peptides inhibit synaptic transmission via presynaptic GABAB receptors in CA1 area of rat hippocampal slices

1996 • 34 citations

Target cells during early SIV encephalopathy

1993 • 32 citations

Suppression of neurocognitive damage in LP‐BM5‐infected mice with a targeted deletion of the TNF‐α gene

2000 • 30 citations

Gliosis in the LP-BM5 murine leukemia virus-infected mouse: an animal model of retrovirus-induced dementia

1996 • 24 citations

Evidence of neuronal degeneration in C57Bl/6 mice infected with the LP-BM5 leukemia retrovirus mixture

1998 • 24 citations

Age-dependent changes in the immunoreactivity for neurofilaments in rabbit hippocampus

1997 • 24 citations

No loss of hippocampal neurons in AIDS patients

2000 • 22 citations

Selected Models of HIV-Induced Neurological Disease

1995 • 19 citations

Effects of 2,5-hexanedione on calpain-mediated degradation of human neurofilaments in vitro

2000 • 16 citations

Protein Synthesis Inhibition in Neocortical Grafts Evaluated by Systemic Amino Acid Uptake Autoradiography

2000 • 1 citations