Receptor specificity in the self-renewal and differentiation of primary multipotential hemopoietic cells

Embryonic Stem Cell Lines Derived from Human Blastocysts

1998 • 15,541 citations

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

2000 • 2,528 citations

Bone Marrow as a Potential Source of Hepatic Oval Cells

1999 • 2,439 citations

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

1997 • 2,205 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow

2000 • 1,859 citations

Dystrophin expression in the mdx mouse restored by stem cell transplantation

1999 • 1,817 citations

From Marrow to Brain: Expression of Neuronal Phenotypes in Adult Mice

2000 • 1,709 citations

Turning Brain into Blood: A Hematopoietic Fate Adopted by Adult Neural Stem Cells in Vivo

1999 • 1,437 citations

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

1994 • 1,081 citations

Hematopoietic potential of stem cells isolated from murine skeletal muscle

1999 • 960 citations

Translating Stem and Progenitor Cell Biology to the Clinic: Barriers and Opportunities

2000 • 868 citations

Controlling Signal Transduction with Synthetic Ligands

1993 • 815 citations

Multilineage gene expression precedes commitment in the hemopoietic system.

1997 • 757 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 729 citations

IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo

1985 • 718 citations

Versatile retroviral vectors for potential use in gene therapy.

1994 • 690 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 637 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient Mice

1997 • 603 citations

Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl

1996 • 589 citations

Redesigning an FKBP–ligand interface to generate chemical dimerizers with novel specificity

1998 • 522 citations

Bcl-2 Can Rescue T Lymphocyte Development in Interleukin-7 Receptor–Deficient Mice but Not in Mutant rag-1 −/− Mice

1997 • 503 citations

Smad2 Signaling in Extraembryonic Tissues Determines Anterior-Posterior Polarity of the Early Mouse Embryo

1998 • 469 citations

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

1984 • 447 citations

GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts.

1995 • 430 citations

PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors

1998 • 425 citations

Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin

1998 • 389 citations

Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors

1993 • 380 citations

Role of c-mpl in Early Hematopoiesis

1998 • 362 citations

Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice

1997 • 292 citations

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

1986 • 288 citations

Lineage Commitment and Maturation in Hematopoietic Cells: The Case for Extrinsic Regulation

1998 • 243 citations

Enforced Expression of the GATA-2 Transcription Factor Blocks Normal Hematopoiesis

1999 • 239 citations

Do Stem Cells Play Dice?

1998 • 212 citations

Cytokine Receptor Expression on Hematopoietic Stem and Progenitor Cells

1997 • 189 citations

Do Stem Cells Play Dice?

1998 • 171 citations

A transcription factor party during blood cell differentiation

1998 • 165 citations

Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells

1994 • 153 citations

The lineage commitment of haemopoietic progenitor cells

1997 • 148 citations

In vivo administration of stem cell factor to mice increases the absolute number of pluripotent hematopoietic stem cells

1993 • 121 citations

A proliferation switch for genetically modified cells

1997 • 108 citations

The Prolactin Receptor and Severely Truncated Erythropoietin Receptors Support Differentiation of Erythroid Progenitors

1997 • 101 citations

In vivo selection using a cell-growth switch

2000 • 97 citations

A Role for G-CSF Receptor Signaling in the Regulation of Hematopoietic Cell Function but Not Lineage Commitment or Differentiation

1999 • 91 citations

A GATA-2/estrogen receptor chimera functions as a ligand-dependent negative regulator of self-renewal

1999 • 90 citations

Control of hematopoietic differentiation: Lack of specificity in signaling by cytokine receptors

1998 • 82 citations

Targeted expansion of genetically modified bone marrow cells

1998 • 76 citations

Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo

1999 • 66 citations

Thrombopoietin Does Not Induce Lineage-Restricted Commitment of Mpl-R Expressing Pluripotent Progenitors But Permits Their Complete Erythroid and Megakaryocytic Differentiation

1997 • 54 citations

Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation.

1994 • 46 citations

Absence of cytokine receptor-dependent specificity in red blood cell differentiation in vivo

1998 • 42 citations