The Prolactin Receptor and Severely Truncated Erythropoietin Receptors Support Differentiation of Erythroid Progenitors

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

1993 • 1,395 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

1995 • 1,027 citations

A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS

1964 • 889 citations

Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria

1996 • 785 citations

Expression cloning of the murine erythropoietin receptor

1989 • 776 citations

Versatile retroviral vectors for potential use in gene therapy.

1994 • 690 citations

Signaling Through the Hematopoietic Cytokine Receptors

1995 • 617 citations

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

1991 • 597 citations

Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors

1993 • 380 citations

A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization

1989 • 370 citations

Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity

1990 • 325 citations

The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains.

1991 • 297 citations

Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.

1995 • 291 citations

Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor

1993 • 283 citations

Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors.

1984 • 233 citations

Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis.

1991 • 231 citations

Growth and Differentiation in the Hemopoietic System

1987 • 220 citations

CYTOKINE RECEPTOR SIGNAL TRANSDUCTION AND THE CONTROL OF HEMATOPOIETIC CELL DEVELOPMENT

1996 • 207 citations

Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.

1996 • 204 citations

A stochastic model of self‐renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture

1982 • 199 citations

Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.

1996 • 181 citations

Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells.

1994 • 159 citations

Mechanism-based design of prolactin receptor antagonists.

1993 • 143 citations

Macrophage lineage switching of murine early pre-B lymphoid cells expressing transduced fms genes.

1990 • 129 citations

Interleukin-3, Erythropoietin, and Prolactin Activate a STAT5-like Factor in Lymphoid Cells

1995 • 128 citations

Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: influence of colony-stimulating factors.

1991 • 117 citations

Functional Regions of the Mouse Thrombopoietin Receptor Cytoplasmic Domain: Evidence for a Critical Region Which Is Involved in Differentiation and Can Be Complemented by Erythropoietin

1996 • 93 citations

Expression of the GM-CSF gene after retroviral transfer in hematopoietic stem cell lines induces synchronous granulocyte-macrophage differentiation

1991 • 87 citations

Investigations of a stochastic model of haemopoiesis.

1973 • 84 citations

Erythropoietin receptor signals both proliferation and erythroid-specific differentiation.

1993 • 83 citations

Production of erythropoietic bursts by progenitor cells from adult human peripheral blood in an improved serum-free medium: role of insulinlike growth factor 1

1991 • 82 citations

Roles of erythropoietin, insulin-like growth factor 1, and unidentified serum factors in promoting maturation of purified murine erythroid colony-forming units

1992 • 78 citations

Tyrosine kinase activation through the extracellular domains of cytokine receptors

1993 • 66 citations

Expression of a constitutively active erythropoietin receptor in primary hematopoietic progenitors abrogates erythropoietin dependence and enhances erythroid colony-forming unit, erythroid burst-forming unit, and granulocyte/macrophage progenitor growth.

1993 • 61 citations

The extended box 2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells

1994 • 61 citations

2 Cytokine receptors and signal transduction

1994 • 52 citations

Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiation.

1994 • 51 citations

Induced expression of c-fms in normal hematopoietic cells shows evidence for both conservation and lineage restriction of signal transduction in response to macrophage colony-stimulating factor

1994 • 46 citations

Monoclonal antibodies against rabbit mammary prolactin receptors. Specific antibodies to the hormone binding domain.

1985 • 32 citations

STATs Find That Hanging Together Can Be Stimulating

1996 • 30 citations

A low-affinity human granulocyte-macrophage colony-stimulating factor/murine erythropoietin hybrid receptor functions in murine cell lines

1993 • 28 citations

Cited By (0)

No citing papers found in database