Post-traumatic inflammation following spinal cord injury

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Matrix Metalloproteinases: A Review

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A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

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Chondroitinase ABC promotes functional recovery after spinal cord injury

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The glial scar and central nervous system repair

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Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection

1996 • 1,440 citations

Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

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Degeneration and regeneration of axons in the lesioned spinal cord

1996 • 1,123 citations

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

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Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

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Functional plasticity of microglia: A review

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Neuronal and Glial Apoptosis after Traumatic Spinal Cord Injury

1997 • 901 citations

Cellular inflammatory response after spinal cord injury in sprague-dawley and lewis rats

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Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

1998 • 794 citations

Regeneration of adult axons in white matter tracts of the central nervous system

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A Monitored Contusion Model of Spinal Cord Injury in the Rat

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Robust Regeneration of Adult Sensory Axons in Degenerating White Matter of the Adult Rat Spinal Cord

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Ischemia-induced neuronal apoptosis

1996 • 600 citations

Activation of CPP32-Like Caspases Contributes to Neuronal Apoptosis and Neurological Dysfunction after Traumatic Brain Injury

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Modulation of life and death by the TNF receptor superfamily

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Acute Inflammatory Response in Spinal Cord Following Impact Injury

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Energetics in the pathogenesis of neurodegenerative diseases

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Matrix Metalloproteinases Limit Functional Recovery after Spinal Cord Injury by Modulation of Early Vascular Events

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Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury

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IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways

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MASCIS Evaluation of Open Field Locomotor Scores: Effects of Experience and Teamwork on Reliability

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Apoptosis after traumatic human spinal cord injury

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Traumatic spinal cord injury induces nuclear factor-kappaB activation.

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Chapter 4 Cell death in models of spinal cord injury

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ProNGF Induces p75-Mediated Death of Oligodendrocytes following Spinal Cord Injury

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Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord

1999 • 409 citations

Systemically Administered Interleukin-10 Reduces Tumor Necrosis Factor-Alpha Production and Significantly Improves Functional Recovery Following Traumatic Spinal Cord Injury in Rats

1999 • 404 citations

Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat

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Chapter 6 Glutamate receptors and the induction of excitotoxic neuronal death

1994 • 387 citations

Traumatic Spinal Cord Injury Induces Nuclear Factor-κB Activation

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Vascular Events After Spinal Cord Injury: Contribution to Secondary Pathogenesis

2000 • 379 citations

Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats

1997 • 371 citations

Expression of Pro‐Inflammatory Cytokine and Chemokine mRNA Upon Experimental Spinal Cord Injury in Mouse: an In Situ Hybridization Study

1997 • 354 citations

Vascular mechanisms in the pathophysiology of human spinal cord injury

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The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats

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Laminin is induced in astrocytes of adult brain by injury.

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Modulating astrogliosis after neurotrauma

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Activated Macrophages and the Blood–Brain Barrier: Inflammation after CNS Injury Leads to Increases in Putative Inhibitory Molecules

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The CNS lesion scar: new vistas on an old regeneration barrier

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Interleukin-10 Improves Outcome and Alters Proinflammatory Cytokine Expression after Experimental Traumatic Brain Injury

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Free radicals in central nervous system ischemia.

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Mechanisms of cell death in hypoxia/reoxygenation injury

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Sequential mRNA Expression for Immediate Early Genes, Cytokines, and Neurotrophins in Spinal Cord Injury

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Spinal Cord Injury Produced by Consistent Mechanical Displacement of the Cord in Rats: Behavioral and Histologic Analysis

1992 • 247 citations

Age-related effects of interleukin-1 beta on polymorphonuclear neutrophil-dependent increases in blood-brain barrier permeability in rats

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Glial cell extracellular matrix: boundaries for axon growth in development and regeneration

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A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device

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Intracerebral administration of interleukin-1β and induction of inflammation, apoptosis, and vasogenic edema

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Protective Effect of the Energy Precursor Creatine Against Toxicity of Glutamate and β‐Amyloid in Rat Hippocampal Neurons

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Spinal cord injury in the rat

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Oxygen free radicals regulate NMDA receptor function via a redox modulatory site

1990 • 205 citations

Effects of pro-inflammatory cytokines in experimental spinal cord injury

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Modeling of Acute Spinal Cord Injury in the Rat: Neuroprotection and Enhanced Recovery with Methylprednisolone, U-74006F and YM-14673

1994 • 186 citations

Cytokine-induced Acute Inflammation in the Brain and Spinal Cord

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Glutamate neurotoxicity in spinal cord cell culture

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Effects of Interleukin-10 (IL-10) on Pain Behavior and Gene Expression Following Excitotoxic Spinal Cord Injury in the Rat

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Neurotoxin induced nerve cell degeneration: Possible involvement of calcium

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Astrocytes Are the Major Source of Nerve Growth Factor Upregulation Following Traumatic Brain Injury in the Rat

1998 • 161 citations

Increase of interleukin-1β mRNA and protein in the spinal cord following experimental traumatic injury in the rat

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Spinal Cord Injury Elicits Expression of Keratan Sulfate Proteoglycans by Macrophages, Reactive Microglia, and Oligodendrocyte Progenitors

2002 • 156 citations

Neuronal, astroglial and microglial cytokine expression after an excitotoxic lesion in the immature rat brain

2000 • 154 citations

Role of Tumor Necrosis Factor-α in Neuronal and Glial Apoptosis after Spinal Cord Injury

2000 • 153 citations

Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion

2002 • 148 citations

Chapter 23 The extracellular matrix in axon regeneration

2002 • 148 citations

Diffusion anisotropy MRI for quantitative assessment of recovery in injured rat spinal cord

2001 • 137 citations

Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration

2000 • 134 citations

Postischemic Hypothermia and IL-10 Treatment Provide Long-Lasting Neuroprotection of CA1 Hippocampus Following Transient Global Ischemia in Rats

1999 • 127 citations

Posttraumatic Hypothermia Reduces Polymorphonuclear Leukocyte Accumulation Following Spinal Cord Injury in Rats

2000 • 124 citations

Development and Characterization of a Novel, Graded Model of Clip Compressive Spinal Cord Injury in the Mouse: Part 2. Quantitative Neuroanatomical Assessment and Analysis of the Relationships between Axonal Tracts, Residual Tissue, and Locomotor Recovery

2002 • 124 citations

Beneficial effects of modest systemic hypothermia on locomotor function and histopathological damage following contusion-induced spinal cord injury in rats

2000 • 121 citations

Delivery of hyper‐interleukin‐6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth

2002 • 119 citations

Immunological regulation of neuronal degeneration and regeneration in the injured spinal cord

2000 • 116 citations

Basic Fibroblast Growth Factor (bFGF) Enhances Tissue Sparing and Functional Recovery Following Moderate Spinal Cord Injury

1999 • 113 citations

Peroxynitrite generated in the rat spinal cord induces neuron death and neurological deficits

2002 • 111 citations

Apoptosis following spinal cord injury in rats and preventative effect of N-methyl-d-aspartate receptor antagonist

1999 • 106 citations

Circulating levels of IL-2R, ICAM-1, and IL-6 in spinal cord injuries

1997 • 103 citations

Myelin Gene Expression after Experimental Contusive Spinal Cord Injury

1998 • 95 citations

Tenascin-C expression and axonal sprouting following injury to the spinal dorsal columns in the adult rat

1997 • 89 citations

Differential Activation of Microglia After Experimental Spinal Cord Injury

1999 • 85 citations

Cell death and plasticity after experimental spinal cord injury

2000 • 84 citations

Rapid changes in expression of glutamate transporters after spinal cord injury

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Experimental modelling of human spinal cord injury: a model that crosses the species barrier and mimics the spectrum of human cytopathology

2002 • 78 citations

Changes in Metabotropic Glutamate Receptor Expression Following Spinal Cord Injury

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Spinal cord repair: from experimental models to human application

1998 • 75 citations

Upregulation of RGS7 may contribute to tumor necrosis factor-induced changes in central nervous function

1999 • 72 citations

Increase in TNFα Transport after SCI Is Specific for Time, Region, and Type of Lesion

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Role of Leukocytes in Spinal Cord Injury in Rats

2000 • 61 citations

Protective effects of oral creatine supplementation on spinal cord injury in rats

2002 • 61 citations

Neurobiology of Spinal Cord Injury

2000 • 52 citations

Changes in Nitric Oxide and Expression of Nitric Oxide Synthase in Spinal Cord after Acute Traumatic Injury in Rats

2002 • 50 citations

Involvement of metabotropic glutamate receptors in excitatory amino acid and GABA release following spinal cord injury in rat

2001 • 49 citations

Protective autoimmunity as a T-cell response to central nervous system trauma: prospects for therapeutic vaccines

2001 • 47 citations

Effects of dexamethasone on apoptosis-related cell death after spinal cord injury

2002 • 42 citations

Presence and significance of CD-95 (Fas/APO1) expression after spinal cord injury

2001 • 38 citations

Traumatic Brain Tissue Acidosis: Experimental and Clinical Studies

1993 • 38 citations

The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury

2001 • 37 citations

Changes of Fas and Fas ligand immunoreactivity after compression trauma to rat spinal cord

2000 • 34 citations

The vulnerability of spinal cord neurons to excitotoxic injury: Comparison with cortical neurons

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Autoimmune involvement in CNS trauma is beneficial if well controlled

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Inflammatory Cells and Mediators in CNS Disease

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Somatostatin-like immunoreactivity in human sympathetic ganglia

1987 • 23 citations

Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats

2002 • 22 citations

Increased expression of the putative axon growth-repulsive extracellular matrix molecule, keratan sulphate proteoglycan, following traumatic injury of the adult rat spinal cord

2002 • 20 citations

Kainate‐induced excitotoxicity is dependent upon extracellular potassium concentrations that regulate the activity of AMPA/KA type glutamate receptors

2002 • 18 citations

Intracellular Signal Transduction

2001 • 13 citations

Strategies for Spinal Cord Repair

2000 • 7 citations

Neurobiology of spinal cord injury

2001 • 5 citations

Calcium and Neuronal Death in Spinal Neurons

2000 • 4 citations