Matrix Metalloproteinases Limit Functional Recovery after Spinal Cord Injury by Modulation of Early Vascular Events

A Sensitive and Reliable Locomotor Rating Scale for Open Field Testing in Rats

1995 • 4,199 citations

How Matrix Metalloproteinases Regulate Cell Behavior

2001 • 3,860 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1981 • 1,582 citations

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

1997 • 1,311 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Cerebral microvascular pathology in aging and Alzheimer's disease

2001 • 1,041 citations

Metalloproteinases in biology and pathology of the nervous system

2001 • 1,032 citations

Matrix Metalloproteinases and TIMPs Are Associated With Blood-Brain Barrier Opening After Reperfusion in Rat Brain

1998 • 847 citations

Matrix Metalloproteinase Expression Increases After Cerebral Focal Ischemia in Rats

1998 • 731 citations

Secondary Cell Death and the Inflammatory Reaction After Dorsal Hemisection of the Rat Spinal Cord

1994 • 531 citations

The role of cerebral ischemia in Alzheimer’s disease

2000 • 521 citations

Acute Inflammatory Response in Spinal Cord Following Impact Injury

1998 • 486 citations

MASCIS Evaluation of Open Field Locomotor Scores: Effects of Experience and Teamwork on Reliability

1996 • 441 citations

Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membrane.

1996 • 416 citations

Proteolytic Cascade Enzymes Increase in Focal Cerebral Ischemia in Rat

1996 • 408 citations

Tissue Destruction by Neutrophils

1989 • 389 citations

The Serpin α1-Proteinase Inhibitor Is a Critical Substrate for Gelatinase B/MMP-9 In Vivo

2000 • 371 citations

Role of neutrophils in spinal cord injury in the rat

1997 • 355 citations

Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood–brain barrier breakdown in vivo

1998 • 354 citations

Matrix Metalloproteinases in Cerebrovascular Disease

1998 • 353 citations

Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40).

1996 • 341 citations

Early appearance of activated matrix metalloproteinase-9 and blood–brain barrier disruption in mice after focal cerebral ischemia and reperfusion

1999 • 340 citations

Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases.

1994 • 338 citations

Guidebook to the extracellular matrix, anchor, and adhesion proteins

1999 • 336 citations

Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat

1997 • 307 citations

Delayed Demyelination and Macrophage Invasion: A Candidate for Secondary Cell Damage in Spinal Cord Injury

1985 • 295 citations

Matrix Metalloproteinases in the Normal Human Central Nervous System, Microglial Nodules, and Multiple Sclerosis Lesions

1996 • 290 citations

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis

1996 • 278 citations

Spinal cord contusion in the rat: Morphometric analyses of alterations in the spinal cord☆

1985 • 274 citations

Matrix Metalloproteinase-9/Gelatinase B Is Required for Process Outgrowth by Oligodendrocytes

1999 • 268 citations

Differential matrix metalloproteinase expression in cases of multiple sclerosis and stroke

1997 • 265 citations

Tumor necrosis factor-α-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window

1995 • 260 citations

A Quantitative Spatial Analysis of the Blood–Spinal Cord Barrier

1996 • 247 citations

The Expression of Tissue-type Plasminogen Activator, Matrix Metalloproteases and Endogenous Inhibitors in the Central Nervous System in Multiple Sclerosis

1996 • 247 citations

Gelatinase B–deficient Mice Are Resistant to Experimental Bullous Pemphigoid

1998 • 236 citations

Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.

1987 • 235 citations

Correlative analyses of lesion development and functional status after graded spinal cord contusive injuries in the rat

1989 • 234 citations

Gelatinase B modulates selective opening of the blood-brain barrier during inflammation

1998 • 233 citations

Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase

1989 • 233 citations

Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoid

2001 • 222 citations

Metalloproteinases mediate extracellular matrix degradation by cells from mouse blastocyst outgrowths

1992 • 221 citations

Distribution and time course of protein extravasation in the rat spinal cord after contusive injury

1989 • 218 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activity.

1986 • 215 citations

Regulation of Matrix Metalloproteinase Expression in Astrocytes, Microglia and Neurons

1996 • 211 citations

Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein

1993 • 192 citations

Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in the rat

1995 • 186 citations

Demyelination and remyelination after acute spinal cord compression

1973 • 182 citations

Gelatinase B: Structure, Regulation, and Function

1998 • 176 citations

Effects of silica on the outcome from experimental spinal cord injury: Implication of macrophages in secondary tissue damage

1994 • 175 citations

A Mouse Model of Graded Contusive Spinal Cord Injury

1998 • 132 citations

Matrilysin Is Much More Efficient Than Other Matrix Metalloproteinases in the Proteolytic Inactivation of α1-Antitrypsin

1994 • 128 citations

Matrix Metalloproteinases in the Neocortex and Spinal Cord of Amyotrophic Lateral Sclerosis Patients

1996 • 123 citations

Glucocorticoid Receptor-Mediated Suppression of Activator Protein-1 Activation and Matrix Metalloproteinase Expression after Spinal Cord Injury

2001 • 118 citations

The blood‐brain barrier: Morphology, molecules, and neurothelin

1993 • 118 citations

Injury-induced 92-kilodalton gelatinase and urokinase expression in rat brain.

1994 • 115 citations

Limited proteolysis by macrophage elastase inactivates human alpha 1-proteinase inhibitor.

1980 • 107 citations

Nerve fibres in spinal cord impact injuries

1983 • 102 citations

Purification of a Type V Collagen Degrading Metalloproteinase from Rabbit Alveolar Macrophages

1984 • 98 citations

Role of neutrophil elastase in compression-induced spinal cord injury in rats

1998 • 74 citations

Neutral proteases and disruption of the blood–brain barrier in rat

1997 • 70 citations

A Quantitative Spatial Analysis of the Blood–Spinal Cord Barrier

1996 • 58 citations

The Rev axis of HIV-1 and its associated host cofactors: A viral window onto the workings of eukaryotic posttranscriptional RNA processing

1996 • 46 citations

Expression of extracellular matrix-degrading metalloproteinases and metalloproteinase inhibitors is developmentally regulated during endoderm differentiation of embryonal carcinoma cells

1990 • 41 citations

Differential matrix metalloproteinase expression in cases of multiple sclerosis and stroke

1997 • 24 citations

Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoid

2001 • 19 citations

Correlation in the expression of type IV collagenase and the invasive and chemotactic abilities of myelomonocytic cells during differentiation into macrophages.

1992 • 18 citations