Molecular insights into eukaryotic chemotaxis

Integrins: A family of cell surface receptors

1987 • 4,322 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

Turning off the signal: desensitization of β‐adrenergic receptor function

1990 • 1,241 citations

Lutropin-Choriogonadotropin Receptor: An Unusual Member of the G Protein-Coupled Receptor Family

1989 • 955 citations

Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors.

1977 • 905 citations

Spiral Calcium Wave Propagation and Annihilation in Xenopus laevis Oocytes

1991 • 720 citations

The chemotactic receptor for human C5a anaphylatoxin

1991 • 660 citations

Purification and Complementary DNA Cloning of a Receptor for Basic Fibroblast Growth Factor

1989 • 660 citations

A family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 636 citations

Two Different Subunits Associate to Create Isoform-Specific Platelet-derived Growth Factor Receptors

1989 • 633 citations

Cloning and Sequencing of Porcine LH-hCG Receptor cDNA: Variants Lacking Transmembrane Domain

1989 • 568 citations

Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor

1989 • 523 citations

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1979 • 522 citations

Gene Transfer and Molecular Cloning of the Human NGF Receptor

1986 • 447 citations

The locomotion of fibroblasts in culture I. Movements of the leading edge

1970 • 389 citations

Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain

1988 • 326 citations

Role of attachment factors and attractants in fibroblast chemotaxis.

1980 • 223 citations

Quantitative analysis of cell motility and chemotaxis in Dictyostelium discoideum by using an image processing system and a novel chemotaxis chamber providing stationary chemical gradients.

1989 • 205 citations

Mechanisms of sensing chemical gradients by polymorphonuclear leukocytes

1974 • 198 citations

Chemoattractant-elicited increases in myosin phosphorylation in dictyostelium

1985 • 173 citations

Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library.

1989 • 171 citations

B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.

1990 • 169 citations

Chemoattractant-stimulated polymorphonuclear leukocytes contain two populations of actin filaments that differ in their spatial distributions and relative stabilities.

1990 • 165 citations

Molecular genetic analysis of two G alpha protein subunits in Dictyostelium.

1991 • 153 citations

Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium.

1991 • 148 citations

Regulation of human neutrophil chemotaxis by intracellular pH.

1986 • 145 citations

Kinetic analysis of chemotactic peptide receptor modulation

1982 • 137 citations

Selection of Dictyostelium mutants defective in cytoskeletal proteins: use of an antibody that binds to the ends of alpha-actinin rods.

1986 • 128 citations

Changes in actin associated with the cytoskeleton following chemotactic stimulation of Dictyostelium discoideum

1983 • 127 citations

Cell signalling by second messenger waves

1991 • 127 citations

Targeted disruption of the ABP-120 gene leads to cells with altered motility.

1992 • 125 citations

Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum.

1975 • 125 citations

Excitation, adaption, and deadaptation of the cAMP-mediated cGMP Response in dictyostelium discoideum

1983 • 121 citations

Calcium influx stimulates a second pathway for sustained diacylglycerol production in leukocytes activated by chemoattractants.

1988 • 119 citations

Cyclic 3',5'-AMP relay in Dictyostelium discoideum III. The relationship of cAMP synthesis and secretion during the cAMP signaling response.

1980 • 111 citations

Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium.

1989 • 110 citations

Consequences of chemotactic peptide receptor modulation for leukocyte orientation.

1981 • 107 citations

Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family.

1991 • 103 citations

Molecular cloning of the fMet-Leu-Phe receptor from neutrophils

1990 • 101 citations

Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum.

1988 • 99 citations

A Ca2+ transport system associated with the plasma membrane of Dictyostelium discoideum is activated by different chemoattractant receptors.

1991 • 94 citations

Involvement of GTP-binding proteins in actin polymerization in human neutrophils.

1990 • 84 citations

The formylpeptide chemoattractant receptor copurifies with a GTP-binding protein containing a distinct 40-kDa pertussis toxin substrate.

1988 • 80 citations

Identification of actin nucleation activity and polymerization inhibitor in ameboid cells: their regulation by chemotactic stimulation.

1989 • 69 citations

Chemoattractant-stimulated GTPase activity is decreased on membranes from polymorphonuclear leukocytes incubated in chemoattractant

1989 • 69 citations

Down-regulation of cell surface cyclic AMP receptors and desensitization of cyclic AMP-stimulated adenylate cyclase by cyclic AMP in Dictyostelium discoideum. Kinetics and concentration dependence.

1987 • 47 citations

Transduction of the chemotactic signal to the actin cytoskeleton of Dictyostelium discoideum

1989 • 45 citations

Formyl peptide-induced chemotaxis of human polymorphonuclear leukocytes does not require either marked changes in cytosolic calcium or specific granule discharge. Role of formyl peptide receptor reexpression (or recycling).

1989 • 41 citations

The specificity of the cAMP receptor mediating activation of adenylate cyclase in Dictyostelium discoideum

1986 • 41 citations

Cyclic AMP induces a transient alkalinization in Dictyostelium

1987 • 33 citations

Normal chemotaxis in Dictyostelium discoideum cells with a depolarized plasma membrane potential

1990 • 31 citations

Leukocyte chemoattraction by 1,2-diacylglycerol.

1988 • 30 citations

The role of methylation in chemotaxis. An explanation of outstanding anomalies.

1990 • 20 citations

Signal transduction for chemotaxis in Dictyostelium amoebae.

1990 • 15 citations

Dynamics and function of the inositolcycle in Dictyostelium discoideum

1991 • 8 citations