The dictyostelium essential light chain is required for myosin function

Electron microscope studies on the structure of natural and synthetic protein filaments from striated muscle

1963 • 1,452 citations

Mechanism of adenosine triphosphate hydrolysis by actomyosin

1971 • 1,289 citations

[18] Purification of muscle actin

1982 • 1,186 citations

Regulation and Kinetics of the Actin-Myosin-ATP Interaction

1980 • 1,077 citations

Substructure of the myosin molecule

1971 • 1,062 citations

The Function of Myosin and Myosin Light Chain Kinase Phosphorylation in Smooth Muscle

1985 • 1,052 citations

Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination

1987 • 984 citations

Antisense RNA Inactivation of Myosin Heavy Chain Gene Expression in Dictyostelium discoideum

1987 • 677 citations

Chapter 2 Cultivation and Synchronous Morphogenesis of Dictyostelium under Controlled Experimental Conditions

1987 • 610 citations

Fluorescent antibody localization of myosin in the cytoplasm, cleavage furrow, and mitotic spindle of human cells.

1976 • 539 citations

Acanthamoeba Myosin

1973 • 513 citations

Muscle Contraction and Free Energy Transduction in Biological Systems

1985 • 446 citations

The effect of myosin antibody on the division of starfish blastomeres

1977 • 445 citations

Cytoplasmic Structure and Contractility in Amoeboid Cells

1979 • 343 citations

Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain

1988 • 326 citations

Myosin I is located at the leading edges of locomoting Dictyostelium amoebae

1989 • 323 citations

Localization of actin and myosin for the study of ameboid movement in Dictyostelium using improved immunofluorescence.

1984 • 306 citations

Studies on the role of myosin alkali light chains

1977 • 300 citations

Gene replacement in Dictyostelium: generation of myosin null mutants.

1989 • 299 citations

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila

1991 • 281 citations

Capping of surface receptors and concomitant cortical tension are generated by conventional myosin

1989 • 274 citations

Cytoplasmic myosin from Drosophila melanogaster.

1986 • 256 citations

Regulation of myosin self-assembly: phosphorylation of Dictyostelium heavy chain inhibits formation of thick filaments.

1980 • 252 citations

In pursuit of myosin function.

1989 • 252 citations

Reversible cyclic AMP-dependent change in distribution of myosin thick filaments in Dictyostelium

1985 • 250 citations

Biochemical and structural studies of actomyosin-like proteins from non-muscle cells

1974 • 230 citations

Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium

1985 • 225 citations

Developmental Regulation of Dictyostelium discoideum Actin Gene Fusions Carried on Low-Copy and High-Copy Transformation Vectors

1986 • 221 citations

Dominant effects of tubulin overexpression in Saccharomyces cerevisiae.

1989 • 191 citations

Hydrolysis of ATP and reversible binding to F-actin by myosin heavy chains free of all light chains

1981 • 185 citations

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant.

1990 • 173 citations

Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein.

1987 • 166 citations

Genetic dissection of Drosophila myofibril formation: effects of actin and myosin heavy chain null alleles.

1989 • 156 citations

Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium.

1991 • 148 citations

The free heavy chain of vertebrate skeletal myosin subfragment 1 shows full enzymatic activity.

1982 • 145 citations

Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors.

1986 • 139 citations

Chapter 19 Agar-Overlay Immunofluorescence: High-Resolution Studies of Cytoskeletal Components and Their Changes during Chemotaxis

1987 • 138 citations

Subunit Structure of Myosin

1969 • 137 citations

Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform.

1990 • 137 citations

Electron microscopy of scallop myosin

1983 • 132 citations

Posttranslational Regulation of Keratins: Degradation of Mouse and Human Keratins 18 and 8

1989 • 121 citations

Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function.

1987 • 118 citations

Regulatory properties of single-headed fragments of scallop myosin

1979 • 115 citations

Light Chains of Myosin

1969 • 107 citations

Actin activation of Ca2+-sensitive Mg2+-ATPase activity of Acanthamoeba myosin II is enhanced by dephosphorylation of its heavy chains.

1980 • 104 citations

Domains, motions and regulation in the myosin head

1988 • 97 citations

Effects of cAMP on single cell motility in Dictyostelium.

1984 • 97 citations

Spatial and temporal control of nonmuscle myosin localization: identification of a domain that is necessary for myosin filament disassembly in vivo.

1991 • 90 citations

Relation of structure to function in myosin. II. Salt denaturation and recombination experiments

1970 • 89 citations

Hybrid formation between scallop myofibrils and foreign regulatory light-chains

1980 • 85 citations

Intermolecular versus intramolecular interactions of Dictyostelium myosin: possible regulation by heavy chain phosphorylation.

1989 • 85 citations

Antisense RN

1990 • 85 citations

Cell division in Dictyostelium with special emphasis on actomyosin organization in cytokinesis

1991 • 76 citations

Regulation of smooth muscle myosin

1991 • 75 citations

Light-chain movement and regulation in scallop myosin

1983 • 73 citations

Posttranslational regulation of keratins: degradation of mouse and human keratins 18 and 8.

1989 • 66 citations

Substructure of the myosin molecule. Production and properties of the alkali subunits

1968 • 65 citations

Mapping myosin light chains by immunoelectron microscopy. Use of anti-fluorescyl antibodies as structural probes.

1989 • 61 citations

Tryptic digestion of scallop S1: evidence for a complex between the two light-chains and a heavy-chain peptide

1984 • 57 citations

Relation of structure to function in myosin. I. Subunit dissociation in concentrated salt solutions

1970 • 55 citations

Expression of Dictyostelium myosin tail segments in Escherichia coli: domains required for assembly and phosphorylation.

1990 • 55 citations

Localisation of light chain and actin binding sites on myosin

1986 • 55 citations

Chemoattractant‐elicited translocation of myosin in motile Dictyostelium

1989 • 52 citations

Dictyostelium discoideum myosin: isolation and characterization of cDNAs encoding the essential light chain.

1988 • 47 citations

Calcium regulation of porcine aortic myosin.

1981 • 46 citations

The essential light chains constitute part of the active site of smooth muscle myosin

1986 • 43 citations

Position of the amino terminus of myosin light chain 1 and light chain 2 determined by electron microscopy with monoclonal antibody

1987 • 38 citations

Immunochemical analysis of the supramolecular structure of myosin in contractile cytoskeletons of Dictyostelium amoebae.

1985 • 37 citations

Expression in Escherichia coli of a functional Dictyostelium myosin tail fragment.

1987 • 37 citations

Regulation of scallop myosin by mutant regulatory light chains

1990 • 35 citations

Regulatory and essential light-chain-binding sites in myosin heavy chain subfragment-1 mapped by site-directed mutagenesis

1989 • 33 citations

Inhibition of acanthamoeba actomyosin-II ATPase activity and mechanochemical function by specific monoclonal antibodies.

1984 • 32 citations

Localization of a light-chain binding site on smooth muscle myosin revealed by light-chain overlay of sodium dodecyl sulfate-polyacrylamide electrophoretic gels.

1984 • 31 citations

Regulatory and essential light-chain interactions in scallop myosin

1982 • 27 citations

Identification of sequences necessary for the association of cardiac myosin subunits.

1991 • 21 citations

Small sub-units of myosin

1967 • 20 citations

The actin‐activated ATPase of regulated and unregulated scallop heavy meromyosin

1986 • 18 citations

Involvement of 17K Dalton Light Chain of Smooth Muscle Myosin in Substrate-Induced Conformational Change

1980 • 16 citations

Dictyostelium discoideum essential myosin light chain: Gene structure and characterization

1991 • 16 citations

Expression and organization of BP74, a cyclic AMP-regulated gene expressed during Dictyostelium discoideum development.

1989 • 15 citations

Antisense “Pseudogenetics”

1989 • 14 citations

Regulatory Mechanism by the Phosphorylation of 20-kDa Light Chain of Porcine Aorta Smooth Muscle Myosin1

1990 • 12 citations