The small RNAs of Epstein-Barr virus

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1981 • 3,596 citations

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

1988 • 3,446 citations

DNA sequence and expression of the B95-8 Epstein—Barr virus genome

1984 • 2,039 citations

Optimal alignments in linear space

1988 • 1,229 citations

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1990 • 1,003 citations

Tumor suppressor genes

1991 • 775 citations

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1990 • 585 citations

Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus.

1981 • 577 citations

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1992 • 543 citations

Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells.

1991 • 415 citations

Adenovirus virus-associated RNA and translation control

1991 • 387 citations

Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La Lupus antibodies

1982 • 363 citations

Initiation of protein synthesis in mammalian cells

1986 • 359 citations

Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III.

1989 • 340 citations

Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2.

1992 • 325 citations

Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1

1990 • 319 citations

Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII.

1981 • 315 citations

Localization of Epstein-Barr virus-encoded small RNAs by in situ hybridization.

1986 • 307 citations

Morphological transformation of human keratinocytes expressing the LMP gene of Epstein Barr virus

1990 • 299 citations

Early events in Epstein-Barr virus infection of human B lymphocytes

1991 • 297 citations

The Epstein-Barr virus : recent advances

1986 • 274 citations

Abundant expression of EBER1 small nuclear RNA in nasopharyngeal carcinoma. A morphologically distinctive target for detection of Epstein-Barr virus in formalin-fixed paraffin-embedded carcinoma specimens.

1991 • 248 citations

Viral latency and transformation: The strategy of Epstein-Barr virus

1989 • 241 citations

The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation

1991 • 238 citations

Recombinant Epstein-Barr virus with small RNA (EBER) genes deleted transforms lymphocytes and replicates in vitro.

1991 • 220 citations

Structural analyses of EBER1 and EBER2 ribonucleoprotein particles present in Epstein-Barr virus-infected cells

1988 • 217 citations

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system.

1991 • 207 citations

The Double Stranded RNA-Activated Protein Kinase Induced by Interferon: dsRNA-PK

1989 • 202 citations

The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro.

1989 • 202 citations

Characterization of the major Epstein-Barr virus-specific RNA in Burkitt lymphoma-derived cells

1982 • 199 citations

Epstein-Barr virus small nuclear RNAs are not expressed in permissively infected cells in AIDS-associated leukoplakia.

1990 • 184 citations

Epstein-Barr virus small RNA (EBER) genes: Unique transcription units that combine RNA polymerase II and III promoter elements

1989 • 170 citations

Interferon-Induced and Double-Stranded RNA-Activated Enzymes: A Specific Protein Kinase and 2′,5′-Oligoadenylate Synthetases

1991 • 170 citations

Epstein-Barr virus-associated lymphoproliferative disorders.

1992 • 164 citations

Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI

1991 • 162 citations

Virus infection induces redistribution and membrane localization of the nuclear antigen La (SS-B): a possible mechanism for autoimmunity.

1989 • 136 citations

Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase.

1990 • 131 citations

Striking Similarities Are Exhibited by Two Small Epstein-Barr Virus-Encoded Ribonucleic Acids and the Adenovirus-Associated Ribonucleic Acids VAI and VAII

1981 • 129 citations

Influence of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virus

1989 • 124 citations

Expression of Epstein–Barr virus replicative proteins in aids‐related non‐Hodgkin's lymphoma cells

1991 • 117 citations

The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence of RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase

1991 • 111 citations

EAP, a highly conserved cellular protein associated with Epstein-Barr virus small RNAs (EBERs).

1991 • 111 citations

Characterization of the autoantigen La as a nucleic acid-dependent ATPase/dATPase with melting properties

1990 • 110 citations

Correlation of the expression of Epstein-Barr virus latent membrane protein and in situ hybridization with biotinylated BamHI-W probes in Hodgkin's disease.

1992 • 108 citations

Epstein Barr virus (EBV) encoded small RNAs: targets for detection by in situ hybridisation with oligonucleotide probes.

1992 • 107 citations

The War Against the Interferon-induced dsRNA-Activated Protein Kinase: Can Viruses Win?

1992 • 105 citations

Transient expression of the Epstein-Barr virus LMP1 gene in human primary B cells induces cellular activation and DNA synthesis.

1992 • 101 citations

Two families of sequences in the small RNA-encoding region of Epstein-Barr virus (EBV) correlate with EBV types A and B

1989 • 98 citations

Identification of transcribed regions of Epstein-Barr virus DNA in Burkitt lymphoma-derived cells

1979 • 97 citations

The retinoblastoma gene and cell growth control

1990 • 91 citations

Isolation and characterization of the genes for two small RNAs of herpesvirus papio and their comparison with Epstein-Barr virus-encoded EBER RNAs

1988 • 87 citations

Translational control by the Epstein‐Barr virus small RNA EBER‐1

1990 • 84 citations

Construction and analysis of additional adenovirus substitution mutants confirm the complementation of VAI RNA function by two small RNAs encoded by Epstein-Barr virus

1985 • 79 citations

The La antigen shuttles between the nucleus and the cytoplasm in CV-1 cells

1989 • 73 citations

Localization of Epstein-Barr virus-encoded RNAs EBER-1 and EBER-2 in interphase and mitotic Burkitt lymphoma cells.

1992 • 67 citations

In vitrotranscription of two Epstein-Barr virus specified small RNA molecules

1982 • 62 citations

Intracellular Distribution of the La Antigen in CV-1 Cells after Herpes Simplex Virus Type 1 Infection Compared with the Localization of U Small Nuclear Ribonucleoprotein Particles

1989 • 61 citations

Epstein-Barr virus-encoded small RNAs (EBERs) do not modulate interferon effects in infected lymphocytes

1992 • 57 citations

Functional Expression and RNA Binding Analysis of the Interferon-Induced, Double-Stranded RNA-Activated, 68,000-M_r Protein Kinase in a Cell-Free System

1991 • 56 citations

Cell growth effects of Epstein--Barr virus leader protein

1992 • 51 citations

Epstein–Barr viral DNA in Hodgkin's disease: Amplification and detection using the polymerase chain reaction

1991 • 44 citations

RNA polymerase III-transcribed EBER 1 and 2 transcription units are expressed and hypomethylated in the major Epstein-Barr virus-carrying cell types

1992 • 43 citations

Epstein-Barr Virus In B Lymphocytes: Viral Gene Expression and Function in Latency

1992 • 33 citations

A synthetic peptide substrate for initiation factor-2 kinases

1991 • 30 citations

The substrate specificity of protein kinases which phosphorylate the α subunit of eukaryotic initiation factor 2

1991 • 20 citations

A Gene Expressed in the Endoderm of the Sea Urchin Embryo

1988 • 8 citations

Intracellular location of the two small RNA coded by Epstein-Barr virus genome and their variations according to viral expression

1984 • 1 citations