YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.

1984 • 579 citations

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

1990 • 565 citations

Sequences and Factors: A Guide to MHC Class-II Transcription

1992 • 540 citations

α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

1985 • 498 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

Regulation of Major Histocompatibility Complex Class-II Genes: X, Y and Other Letters of the Alphabet

1990 • 470 citations

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

1988 • 432 citations

Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated

1990 • 377 citations

Yeast HAP1 activator binds to two upstream activation sites of different sequence

1987 • 317 citations

A New Member of the Leucine Zipper Class of Proteins that Binds to the HLA DRα Promoter

1990 • 286 citations

Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H–2 gene

1986 • 252 citations

The Y-box factors: a family of nucleic acid binding proteins conserved from Escherichia coli to man.

1992 • 232 citations

Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription.

1992 • 192 citations

Xenopus Y-box transcription factors: molecular cloning, functional analysis and developmental regulation.

1990 • 192 citations

Improved FACS‐Gal: Flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs

1991 • 192 citations

OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences.

1988 • 184 citations

The murine Eα immune response gene

1983 • 180 citations

Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA.

1988 • 171 citations

MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain.

1990 • 171 citations

Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex.

1983 • 161 citations

Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts.

1986 • 159 citations

Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus.

1991 • 146 citations

A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motif

1992 • 133 citations

Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors.

1990 • 121 citations

Class II genes of the human major histocompatibility complex. The DO beta gene is a divergent member of the class II beta gene family.

1987 • 115 citations

Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line.

1988 • 101 citations

Cloning and Characterization of Chicken YB-1: Regulation of Expression in the Liver

1993 • 84 citations

Isolation and characterization of a cDNA clone for the CCAAT transcription factor EFIA reveals a novel structural motif.

1990 • 82 citations

Identification of an interferon-gamma response region 5' of the human histocompatibility leukocyte antigen DR alpha chain gene which is active in human glioblastoma multiforme lines.

1987 • 78 citations

Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene.

1991 • 73 citations

Sequence Elements Required for Activity of a Murine Major Histocompatibility Complex Class II Promoter Bind Common and Cell-Type-Specific Nuclear Factors

1990 • 68 citations

Two B cell factors bind the HLA-DRA X box region and recognize different subsets of HLA class II promoters

1991 • 65 citations

Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins.

1989 • 63 citations

Dissection of the interferon gamma-MHC class II signal transduction pathway reveals that type I and type II interferon systems share common signalling component(s).

1992 • 56 citations

Multiple regulatory regions on the 5' side of the mouse E alpha gene.

1988 • 55 citations

Molecular cloning and characterization of interferon alpha/beta response element binding factors of the murine (2'-5')oligoadenylate synthetase ME-12 gene.

1991 • 53 citations

Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-gamma-inducible expression of the HLA-DRA gene.

1992 • 47 citations

Negative regulation of the major histocompatibility complex class I promoter in embryonal carcinoma cells.

1991 • 43 citations

X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.

1990 • 41 citations

Sequences homologous to class II MHC W, X, and Y elements mediate constitutive and IFN-gamma-induced expression of human class II-associated invariant chain gene.

1991 • 38 citations

Usage of primary cells to delineate IFN-gamma-responsive DNA elements in the HLA-DRA promoter and to identify a novel IFN-gamma-enhanced nuclear factor.

1992 • 38 citations

Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes.

1990 • 36 citations

Mutant human cells defective in induction of major histocompatibility complex class II genes by interferon gamma.

1993 • 35 citations

Class II Box Consensus Sequences in the HLA-DRα Gene: Transcriptional Function and Interaction with Nuclear Proteins

1989 • 34 citations

Unusual DNA binding characterstics of anin vitrotranslation product of the CCAAT binding protein mYB-1

1992 • 32 citations

Transcriptional regulation of the HLA-DRA gene.

1991 • 32 citations

The IFN-gamma response of the murine invariant chain gene is mediated by a complex enhancer that includes several MHC class II consensus elements.

1990 • 28 citations

The presence of a DNA binding complex correlates with E beta class II MHC gene expression.

1990 • 24 citations

Regulation of the class II-associated invariant chain gene in normal and mutant B lymphocytes.

1990 • 22 citations

Transcriptional Control of the Invariant Chain Gene Involves Promoter and Enhancer Elements Common to and Distinct from Major Histocompatibility Complex Class II Genes

1990 • 15 citations

Functional analysis of cis‐linked regulatory sequences in the HLA DRA promoter by transcription in vitro

1990 • 15 citations

Isolation of the CCAAT transcription factor subunit EFIA cDNA and a potentially functional EFIA processed pseudogene from Bos taurus: insights into the evolution of the EFIA/dbpB/YB-1 gene family

1993 • 15 citations