Immobilization of Notch ligand, Delta-1, is required for induction of Notch signaling

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1998 • 1,600 citations

Signalling downstream of activated mammalian Notch

1995 • 1,375 citations

A Novel Proteolytic Cleavage Involved in Notch Signaling

2000 • 1,080 citations

Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.

1982 • 932 citations

A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1

2000 • 841 citations

The choice of cell fate in the epidermis of Drosophila

1991 • 736 citations

Nuclear Access and Action of Notch In Vivo

1998 • 730 citations

Transient Notch Activation Initiates an Irreversible Switch from Neurogenesis to Gliogenesis by Neural Crest Stem Cells

2000 • 715 citations

Notch Receptor Activation Inhibits Oligodendrocyte Differentiation

1998 • 675 citations

Jagged: A mammalian ligand that activates notch1

1995 • 617 citations

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

2000 • 492 citations

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

1994 • 483 citations

Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells

1992 • 452 citations

Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian

1999 • 413 citations

Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors

2000 • 411 citations

The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells

1998 • 328 citations

The Human Homolog of Rat Jagged1Expressed by Marrow Stroma Inhibits Differentiation of 32D Cells through Interaction with Notch1

1998 • 282 citations

Regulation of neuronal diversity in the Xenopus retina by Delta signalling

1997 • 274 citations

Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila

1994 • 260 citations

Isolation and Functional Analysis of a cDNA for Human Jagged2, a Gene Encoding a Ligand for the Notch1 Receptor

1997 • 192 citations

Human Ligands of the Notch Receptor

1999 • 182 citations

Interchangeability of Caenorhabditis elegans DSL proteins and intrinsic signalling activity of their extracellular domains in vivo

1995 • 159 citations

Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila

1997 • 147 citations

A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells

2000 • 137 citations

A dominant-negative form of Serrate acts as a general antagonist of Notch activation

1997 • 80 citations