HLA class I expression in metastatic melanoma correlates with tumor development during autologous vaccination

Progress in human tumour immunology and immunotherapy

2001 • 1,327 citations

Natural selection of tumor variants in the generation of “tumor escape” phenotypes

2002 • 1,014 citations

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

1997 • 769 citations

Does the Immune System See Tumors as Foreign or Self?

2003 • 746 citations

Tumor antigens recognized by T cells

1997 • 552 citations

Loss of Functional Beta2-Microglobulin in Metastatic Melanomas From Five Patients Receiving Immunotherapy

1996 • 515 citations

Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes

2004 • 368 citations

The selection of tumor variants with altered expression of classical and nonclassical MHC class I molecules: implications for tumor immune escape

2004 • 289 citations

Immunity to cancer: attack and escape in T lymphocyte–tumor cell interaction

2002 • 280 citations

Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2?-deoxycytidine treatment

2001 • 234 citations

Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection

1995 • 225 citations

Immunosurveillance is active in colorectal cancer as downregulation but not complete loss of MHC class I expression correlates with a poor prognosis

2005 • 224 citations

Gene-based vaccines and immunotherapeutics

2004 • 184 citations

Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen

2004 • 155 citations

Total loss of MHC class I is an independent indicator of good prognosis in breast cancer

2005 • 146 citations

Mutations of the β₂‐microglobulin gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides

1998 • 142 citations

Complete loss of HLA class I antigen expression on melanoma cells: A result of successive mutational events

2002 • 97 citations

T-cell responses of vaccinated cancer patients

2003 • 93 citations

Distribution of HLA class I altered phenotypes in colorectal carcinomas: high frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21

2004 • 89 citations

Immunoselection by T lymphocytes generates repeated MHC class I-deficient metastatic tumor variants

2000 • 84 citations

Escape strategies and reasons for failure in the interaction between tumour cells and the immune system: how can we tilt the balance towards immune-mediated cancer control?

2005 • 72 citations

Association of Antigen-Processing Machinery and HLA Antigen Phenotype of Melanoma Cells with Survival in American Joint Committee on Cancer Stage III and IV Melanoma Patients

2006 • 59 citations

Identification of different tumor escape mechanisms in several metastases from a melanoma patient undergoing immunotherapy

2006 • 55 citations

M-Vax: an autologous, hapten-modified vaccine for human cancer

2004 • 52 citations

Phase I/II study of immunotherapy with T-cell peptide epitopes in patients with stage IV melanoma

2004 • 50 citations

Phenotypic and genetic analysis of HLA class I and HLA-DR antigen expression on human melanomas.

1988 • 39 citations

Analysis of HLA class I expression in different metastases from two melanoma patients undergoing peptide immunotherapy

2001 • 35 citations

HLA class I expression on human cancer cells

2000 • 30 citations

Selective monomorphic and polymorphic HLA class I antigenic determinant loss in surgically removed melanoma lesions

2005 • 29 citations

Biological and clinical developments in melanoma vaccines

2001 • 25 citations

HLA-B locus-specific downregulation in human melanoma requires enhancer A as well as a sequence element located downstream of the transcription initiation site

2000 • 19 citations