Immunosurveillance is active in colorectal cancer as downregulation but not complete loss of MHC class I expression correlates with a poor prognosis

Tissue microarrays for high-throughput molecular profiling of tumor specimens

1998 • 4,104 citations

The Three Es of Cancer Immunoediting

2004 • 2,781 citations

In search of the ‘missing self’: MHC molecules and NK cell recognition

1990 • 2,600 citations

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

1997 • 769 citations

Tissue microarray technology for high-throughput molecular profiling of cancer

2001 • 560 citations

Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products.

1986 • 547 citations

MHC antigens and tumor escape from immune surveillance

2001 • 300 citations

HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in Western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy

1990 • 252 citations

β2-Microglobulin-Free HLA Class I Heavy Chain Epitope Mimicry by Monoclonal Antibody HC-10-Specific Peptide

2003 • 153 citations

Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β₂‐microglobulin inactivation in MSI‐positive tumors and LMP7/TAP2 downregulation in MSI‐negative tumors

2003 • 152 citations

Down-Regulation of HLA-A Expression Correlates with a Better Prognosis in Colorectal Cancer Patients

2002 • 128 citations

Natural killer cells infiltrating colorectal cancer and MHC class I expression

2004 • 102 citations

An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide.

1994 • 93 citations

Antigen Presentation By Class I Major Histocompatibility Complex Molecules: A Context for Thinking About HLA‐G

1995 • 37 citations

The Cell Biology of Antigen Presentation

2002 • 34 citations

Reduction or loss of HLA-A,B,C antigens in colorectal carcinoma appears not to influence survival

1988 • 33 citations

p53 and HLA class-I expression are not down-regulated in colorectal cancer liver metastases

2004 • 23 citations

The expression of MHC class I, TAP1/2, and LMP2/7 gene in human gastric cancer cell lines.

2000 • 17 citations

Variation of HLA-ABC surface antigen expression on adenocarcinoma of the colon in correlation with the degree of differentiation.

1990 • 8 citations

Deleted Work

1955 • 0 citations