HLA class I expression on human cancer cells

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

Immunity to Methylcholanthrene-Induced Sarcomas

1957 • 1,241 citations

A p16 ^INK4a -Insensitive CDK4 Mutant Targeted by Cytolytic T Lymphocytes in a Human Melanoma

1995 • 1,147 citations

Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

1994 • 921 citations

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

1993 • 888 citations

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.

1994 • 850 citations

Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes.

1994 • 771 citations

Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.

1960 • 736 citations

A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.

1992 • 694 citations

Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin.

1953 • 686 citations

BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes

1995 • 598 citations

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

1995 • 591 citations

A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes.

1996 • 542 citations

HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance

1998 • 430 citations

Two tyrosinase nonapeptides recognized on HLA‐A2 melanomas by autologous cytolytic T lymphocytes

1994 • 421 citations

A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma.

1995 • 416 citations

Cellular and Humoral immunity to Different Types of Human Neoplasms

1968 • 386 citations

A peptide encoded by human gene MAGE‐3 and presented by HLA‐A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE‐3

1994 • 379 citations

Intradermal Immunization of C3H Mice against a Sarcoma That Originated in an Animal of the Same Line

1943 • 363 citations

TUMOUR-INFILTRATING LYMPHOCYTES AND INTERLEUKIN-2 IN TREATMENT OF ADVANCED CANCER

1989 • 337 citations

Search for tumor-specific immune reactions in Burkitt lymphoma patients by the membrane immunofluorescence reaction.

1966 • 312 citations

Demonstration of cell-bound and humoral immunity against neuroblastoma cells.

1968 • 307 citations

Immunotherapy of cancer with dendritic-cell-based vaccines

1998 • 298 citations

Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein.

1997 • 269 citations

Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas.

1986 • 259 citations

Autologous cytolytic T lymphocytes recognize a MAGE‐1 nonapeptide on melanomas expressing HLA‐Cw* 1601

1994 • 233 citations

Loss of HLA class I expression in prostate cancer: Implications for immunotherapy

1995 • 189 citations

Surgical Adjuvant Active Specific Immunotherapy for Patients with Stage III Melanoma: The Final Analysis of Data from a Phase III, Randomized, Double-Blind, Multicenter Vaccinia Melanoma Oncolysate Trial

1998 • 183 citations

Use of adoptive transfer of tumor-infiltrating lymphocytes alone or in combination with cisplatin-containing chemotherapy in patients with epithelial ovarian cancer.

1991 • 168 citations

Proto-oncogene PML controls genes devoted to MHC class I antigen presentation

1998 • 165 citations

Selective changes in expression of HLA class I polymorphic determinants in human solid tumors.

1989 • 150 citations

Membrane Immunofluorescence Reactions of Burkitt Lymphoma Cells From Biopsy Specimens and Tissue Cultures<xref ref-type="fn" rid="FN1">2</xref>

1967 • 147 citations

Immunization with human papillomavirus type 16 (HPV16) oncoprotein-loaded dendritic cells as well as protein in adjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells.

1998 • 144 citations

High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas

1998 • 143 citations

Loss of transporter in antigen processing 1 transport protein and major histocompatibility complex class I molecules in metastatic versus primary breast cancer.

1995 • 137 citations

Hla Class I Antigens in Human Tumors

1995 • 133 citations

IMMUNOLOGICAL DETERMINANTS OF POLYOMA VIRUS ONCOGENESIS

1962 • 130 citations

Cellular Mucins: Targets for Immunotherapy

2017 • 130 citations

High frequency of altered HLA class I phenotypes in invasive breast carcinomas

1996 • 120 citations

DNA Immunization Targeting the Skin: Molecular Control of Adaptive Immunity

1998 • 106 citations

Human leukocyte antigen class I expression. Marker of poor prognosis in uveal melanoma.

1997 • 102 citations

Cellular Mucins: Targets for Immunotherapy

1994 • 102 citations

Processing and Presentation of Endocytically Acquired Protein Antigens by MHC Class II and Class I Molecules

1996 • 99 citations

Vaccination with IL-7 gene-modified autologous melanoma cells can enhance the anti-melanoma lytic activity in peripheral blood of patients with a good clinical performance status: a clinical phase I study

1998 • 98 citations

Regression of established tumors in mice mediated by the oral administration of a recombinant Listeria monocytogenes vaccine.

1995 • 94 citations

Antibody responses in melanoma patients immunized with an anti-idiotype antibody mimicking disialoganglioside GD2.

1998 • 90 citations

Effect of leukocytes on transplantability of human cancer

1966 • 87 citations

Loss of an HLA haplotype in pancreas cancer tissue and its corresponding tumor derived cell line

1996 • 85 citations

Melanoma patients immunized with melanoma cell vaccine induce antibody responses to recombinant MAGE-1 antigen.

1995 • 78 citations

Gene-based strategies for the immunotherapy of cancer

1997 • 77 citations

Heat shock protein 70 and HLA-DR molecules tissue expression

1995 • 76 citations

Expression of HLA class I and II antigens in bronchogenic carcinomas: its relationship to cellular DNA content and clinical-pathological parameters.

1991 • 74 citations

The new vaccines: building viruses that elicit antitumor immunity

1996 • 72 citations

Search for host defenses in Burkitt lymphoma: membrane immunofluorescence tests on biopsies and tissue culture lines.

1967 • 67 citations

Prognostic Value of HLA-DR Expression and Dendritic Cell Infiltration in Gastric Cancer

1997 • 66 citations

Can the HLA phenotype be used as a prognostic factor in breast carcinomas?

1991 • 56 citations

Transloading of tumor antigen-derived peptides into antigen-presenting cells

1997 • 51 citations

Molecular mimicry of carcinoembryonic antigen by peptides derived from the structure of an anti-idiotype antibody.

1998 • 50 citations

Breast cancer immunotherapy: Current status and future prospects

1996 • 48 citations

Expression of MHC class I and class II antigens in pancreatic adenocarcinomas

1996 • 48 citations

Altered HLA Expression by Metastatic Cervical Carcinoma Cells as a Factor in Impaired Immune Surveillance

1995 • 48 citations

Preparation and characterization of a polyvalent human melanoma antigen vaccine.

1986 • 47 citations

Increased Survival of Patients Treated With a Vaccinia Melanoma Oncolysate Vaccine

1997 • 47 citations

Major Histocompatibility Complex Class I and Class II Expression in Renal Cell Carcinoma and Modulation by Interferon Gamma

1996 • 46 citations

Recombinant Listeria monocytogenes cancer vaccines

1996 • 45 citations

Phase I Study to the Immunotherapy of Metastatic Malignant Melanoma by a Cancer Vaccine Consisting of Autologous Cancer Cells Transfected with the Human IL-2 Gene. University of Vienna, Austria

1996 • 39 citations

Direct Gene Transfer for Treatment of Human Cancer

1995 • 37 citations

Is the survival of melanoma patients receiving polyvalent melanoma cell vaccine linked to the human leukocyte antigen phenotype of patients?

1998 • 33 citations

A Phase I Trial of Human Gamma Interferon Transduced Autologous Tumor Cells in Patients with Disseminated Malignant Melanoma. Duke University Medical Center, Durham, North Carolina

1994 • 30 citations

MHC class I antigens and tumour-infiltrating leucocytes in laryngeal cancer: long-term follow-up

1996 • 27 citations

Active Immunization of Metastatic Melanoma Patients with Interleukin-4 Transduced, Allogeneic Melanoma Cells. A Phase I–II Study. University of Turin, Italy

1994 • 26 citations

Clinical Activity of a Polyvalent Melanoma Antigen Vaccine

1995 • 23 citations

Immunohistochemically demonstrated expression of HLA‐DR antigen in colorectal adenocarcinomas and its relation to clinicopathological features

1995 • 18 citations

Immunotherapy of acute lymphoblastic leukemia by vaccination with autologous leukemic cells transfected with a cDNA expression plasmid coding for an allogeneic HLA class I antigen combined with interleukin-2 treatment

1998 • 16 citations

A comparison of flow cytometry and immunohistochemistry in human colorectal cancers

1998 • 16 citations

Class I major histocompatibility complex antigens and tumor ploidy in breast and bronchogenic carcinomas.

1997 • 16 citations

Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene

1997 • 14 citations

Treatment with tumour infiltrating lymphocytes and interleukin-2 in patients with metastatic melanoma: A pilot study

1992 • 12 citations

Improvement in disease-free survival of melanoma patients in conjunction with serologic response in a phase Ia/Ib Southeastern Cancer Study Group trial of vaccinia melanoma oncolysate.

1989 • 12 citations

Cytokine-based gene therapy of human tumors. An overview.

1996 • 12 citations

Phase I Evaluation of Interleukin-2-Transfected Irradiated Allogeneic Melanoma for the Treatment of Metastatic Melanoma. University of Illinois at Chicago, Chicago, Illinois

1997 • 8 citations

Cytokine Gene Therapy for Human Tumors

1998 • 8 citations

Comparison of Natural Killer (NK) Sensitivities of Two Tumor Cell Lines Established from a Cancer Patient before and after Radiation Therapy

1997 • 4 citations

Immunisation of colorectal cancer patients with autologous tumour cells.

1998 • 2 citations

Deleted Work

1955 • 0 citations