Cyclic Phosphatidic Acid Is Produced by Autotaxin in Blood

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

1997 • 1,085 citations

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

2002 • 908 citations

Identification of Human Plasma Lysophospholipase D, a Lysophosphatidic Acid-producing Enzyme, as Autotaxin, a Multifunctional Phosphodiesterase

2002 • 723 citations

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.

1992 • 577 citations

Transphosphatidylation by Phospholipase D

1967 • 563 citations

The ins and outs of lysophosphatidic acid signaling

2004 • 550 citations

Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid

1999 • 517 citations

GPR92 as a New G12/13- and Gq-coupled Lysophosphatidic Acid Receptor That Increases cAMP, LPA5

2006 • 462 citations

Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways

2002 • 413 citations

Mechanisms of lysophosphatidic acid production

2004 • 293 citations

Nucleotide Pyrophosphatases/Phosphodiesterases on the Move

2000 • 283 citations

Multiple Mechanisms Linked to Platelet Activation Result in Lysophosphatidic Acid and Sphingosine 1-Phosphate Generation in Blood

2002 • 254 citations

Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate.

2003 • 223 citations

Lysophosphatidic Acid Is Constitutively Produced by Human Peritoneal Mesothelial Cells and Enhances Adhesion, Migration, and Invasion of Ovarian Cancer Cells

2006 • 196 citations

Involvement of lysophospholipase D in the production of lysophosphatidic acid in rat plasma

1986 • 165 citations

Phospholipase D and cell signaling

1993 • 161 citations

Naturally Occurring Analogs of Lysophosphatidic Acid Elicit Different Cellular Responses through Selective Activation of Multiple Receptor Subtypes

1998 • 124 citations

Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma

2004 • 114 citations

Physiological and pathophysiological roles of lysophosphatidic acids produced by secretory lysophospholipase D in body fluids

2002 • 90 citations

Inhibition of eukaryotic DNA polymerase alpha with a novel lysophosphatidic acid (PHYLPA) isolated from myxoamoebae of Physarum polycephalum.

1992 • 90 citations

Identification of Residues Responsible for Ligand Recognition and Regioisomeric Selectivity of Lysophosphatidic Acid Receptors Expressed in Mammalian Cells

2005 • 86 citations

Inhibition of tumor invasion and metastasis by a novel lysophosphatidic acid (cyclic LPA)

1999 • 80 citations

Biological functions of a novel lipid mediator, cyclic phosphatidic acid

2002 • 79 citations

Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2

2004 • 77 citations

Purification and Properties of a Membrane-bound Phospholipase A1 from Mycobacterium phlei

1974 • 67 citations

A novel colorimetric assay for the determination of lysophosphatidic acid in plasma using an enzymatic cycling method

2003 • 59 citations

Cyclic phosphatidic acid elicits neurotrophin‐like actions in embryonic hippocampal neurons

2003 • 56 citations

Existence of a bioactive lipid, cyclic phosphatidic acid, bound to human serum albumin

1999 • 54 citations

Metabolic pathways and physiological and pathological significances of lysolipid phosphate mediators

2004 • 52 citations

Metal‐lon stimulation and inhibition of lysophospholipase D which generates bioactive lysophosphatidic acid in rat plasma

1998 • 51 citations

Conversion of Lysophospholipids to Cyclic Lysophosphatidic Acid by Phospholipase D

1996 • 50 citations

Lipid Phosphate Phosphatase-1 and Ca2+ Control Lysophosphatidate Signaling through EDG-2 Receptors

2000 • 45 citations

Inhibition of Cell Proliferation by a Unique Lysophosphatidic Acid, PHYLPA, Isolated from Physarum polycephalum: Signaling Events of Antiproliferative Action by PHYLPA.

1993 • 41 citations

Incorporation and metabolism of 2-acyl lysophospholipids by Escherich1a coli

1981 • 33 citations

Phospholipase D-catalyzed transphosphatidylation in anhydrous organic solvents

2000 • 31 citations

Attenuation by cyclic phosphatidic acid of peritoneal metastasis of azoxymethane‐induced intestinal cancers in Wistar rats

2004 • 29 citations

Selective inhibition of DNA polymerase-α family with chemically synthesized derivatives of PHYLPA, a unique Physarum lysophosphatidic acid

1995 • 26 citations

Isolation of a New Species of Physarum Lysophosphatidic Acid, PHYLPA, and its Effect on DNA Polymerase Activity.

1993 • 23 citations

Synthesis of acyl phosphatidylglycerol from phosphatidylglycerol in Escherichia coli K-12. Evidence for the participation of detergent-resistant phospholipase A and heat-labile membrane-bound factor(s).

1978 • 22 citations

Cyclic phosphatidic acid inhibits RhoA-mediated autophosphorylation of FAK at Tyr-397 and subsequent tumor-cell invasion

2003 • 17 citations

Synthesis of acyl phosphatidylglycerol from phosphatidylglycerol in Escherichia coli K-12

1978 • 17 citations

Bioactions and Synthesis of a Novel Lipid Mediator, Cyclic Phosphatidic Acid

2000 • 5 citations