Selective inhibition of DNA polymerase-α family with chemically synthesized derivatives of PHYLPA, a unique Physarum lysophosphatidic acid

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

1989 • 846 citations

The bioactive phospholipid lysophosphatidic acid is released from activated platelets

1993 • 653 citations

Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells.

1992 • 355 citations

Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin

1992 • 266 citations

Lysophosphatidic acid, but not phosphatidic acid, is a potent Ca2(+)-mobilizing stimulus for fibroblasts. Evidence for an extracellular site of action.

1990 • 264 citations

Phosphatidic acid that accumulates in platelet-derived growth factor-stimulated Balb/c 3T3 cells is a potential mitogenic signal.

1992 • 195 citations

Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin

1989 • 185 citations

Involvement of lysophospholipase D in the production of lysophosphatidic acid in rat plasma

1986 • 165 citations

Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus

1991 • 140 citations

Structural study of immunoaffinity-purified DNA polymerase α-DNA primase complex from calf thymus

1988 • 125 citations

Inhibition of eukaryotic DNA polymerase alpha with a novel lysophosphatidic acid (PHYLPA) isolated from myxoamoebae of Physarum polycephalum.

1992 • 90 citations

[7] Sea urchin nuclear DNA polymerasel

1974 • 86 citations

Lysophosphatidic acid: A bioactive phospholipid with growth factor-like properties

1992 • 75 citations

A factor that activates oscillatory chloride currents in Xenopus oocytes copurifies with a subfraction of serum albumin.

1991 • 65 citations

Synthesis of 1-O-acylglycerol 2,3-cyclic phosphate: Determination of the absolute structure of PHYLPA, a specific inhibitor of DNA polymerase α

1993 • 48 citations

Differences in the regulation of endothelin-1- and lysophosphatidic-acid-stimulated Ins(1,4,5)P3 formation in rat-1 fibroblasts

1991 • 48 citations

Inhibition of Cell Proliferation by a Unique Lysophosphatidic Acid, PHYLPA, Isolated from Physarum polycephalum: Signaling Events of Antiproliferative Action by PHYLPA.

1993 • 41 citations

Novel Properties of DNA Polymerase β with Poly(rA). oligo(dT) Template-Primer1

1979 • 31 citations

The mitogenic activities of phosphatidate are acyl-chain-length dependent and calcium independent in C3H/10T1/2 cells.

1991 • 27 citations

Isolation of a New Species of Physarum Lysophosphatidic Acid, PHYLPA, and its Effect on DNA Polymerase Activity.

1993 • 23 citations

Inhibition of mammalian DNA polymerases by recombinant alpha-interferon and gamma-interferon.

1987 • 18 citations

Stimulation of DNA polymerase .alpha. activity by microtubule-associated proteins

1991 • 18 citations