NADPH Oxidase 1 and Its Derived Reactive Oxygen Species Mediated Tissue Injury and Repair

The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology

2007 • 6,348 citations

Cell transformation by the superoxide-generating oxidase Mox1

1999 • 1,457 citations

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

2009 • 1,435 citations

Vascular NAD(P)H oxidases: specific features, expression, and regulation

2003 • 1,029 citations

Respiratory burst oxidases: the engines of ROS signaling

2011 • 896 citations

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

2010 • 871 citations

VEGF-receptor signal transduction

2003 • 846 citations

Novel gp91 ^phox Homologues in Vascular Smooth Muscle Cells

2001 • 841 citations

A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

2000 • 596 citations

NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair

2011 • 541 citations

Functions and mechanisms of action of CCN matricellular proteins

2008 • 522 citations

TNF-Induced Activation of the Nox1 NADPH Oxidase and Its Role in the Induction of Necrotic Cell Death

2007 • 504 citations

VEGF Receptor Signal Transduction

2001 • 496 citations

Reactive oxygen generated by Nox1 triggers the angiogenic switch

2002 • 473 citations

Redox signaling in angiogenesis: Role of NADPH oxidase

2006 • 470 citations

Nox1 Is Involved in Angiotensin II–Mediated Hypertension

2005 • 460 citations

Upregulation of Nox-Based NAD(P)H Oxidases in Restenosis After Carotid Injury

2002 • 449 citations

Dermal Wound Healing Is Subject to Redox Control

2005 • 426 citations

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

2013 • 352 citations

Molecular composition and regulation of the Nox family NAD(P)H oxidases

2005 • 296 citations

The Angiogenic Factor Cyr61 Activates a Genetic Program for Wound Healing in Human Skin Fibroblasts

2001 • 294 citations

Nox1-dependent Reactive Oxygen Generation Is Regulated by Rac1

2006 • 263 citations

Myocardial Ischemia-Reperfusion Injury, Antioxidant Enzyme Systems, and Selenium: A Review

2007 • 260 citations

Role of gp91 ^phox (Nox2)-Containing NAD(P)H Oxidase in Angiogenesis in Response to Hindlimb Ischemia

2005 • 258 citations

VEGF Signaling Through NADPH Oxidase-Derived ROS

2007 • 238 citations

Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation

2009 • 226 citations

Point Mutations in the Proline-rich Region of p22 Are Dominant Inhibitors of Nox1- and Nox2-dependent Reactive Oxygen Generation

2005 • 224 citations

Tissue distribution and putative physiological function of NOX family NADPH oxidases.

2004 • 207 citations

Cytokine Activation of Nuclear Factor κB in Vascular Smooth Muscle Cells Requires Signaling Endosomes Containing Nox1 and ClC-3

2007 • 206 citations

ROS Are Required for Mouse Spermatogonial Stem Cell Self-Renewal

2013 • 204 citations

Role of TGFβ-Mediated Inflammation in Cutaneous Wound Healing

2006 • 201 citations

NAD(P)H Oxidase 1, a Product of Differentiated Colon Epithelial Cells, Can Partially Replace Glycoprotein 91phox in the Regulated Production of Superoxide by Phagocytes

2003 • 190 citations

The general case for redox control of wound repair

2003 • 189 citations

Nox1-Based NADPH Oxidase Is the Major Source of UVA-Induced Reactive Oxygen Species in Human Keratinocytes

2007 • 182 citations

Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what for?

2010 • 182 citations

Current knowledge on oxidative stress in hepatic ischemia/reperfusion

2013 • 172 citations

NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury

2012 • 166 citations

Oxidative Stress and Ischemia-Reperfusion Injury in Gastrointestinal Tract and Antioxidant, Protective Agents

2007 • 163 citations

Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering

2009 • 149 citations

Nox1 Mediates Basic Fibroblast Growth Factor-Induced Migration of Vascular Smooth Muscle Cells

2007 • 143 citations

NADPH Oxidase-1 Plays a Crucial Role in Hyperoxia-induced Acute Lung Injury in Mice

2009 • 143 citations

The Nox Family of NADPH Oxidases: Friend or Foe of the Vascular System?

2011 • 137 citations

NOX1 Deficiency Protects From Aortic Dissection in Response to Angiotensin II

2007 • 133 citations

Serotonin 5-HT_2Areceptor induces TGF-β1 expression in mesangial cells via ERK: proliferative and fibrotic signals

1999 • 125 citations

Interferon-γ activates transcription of NADPH oxidase 1 gene and upregulates production of superoxide anion by human large intestinal epithelial cells

2005 • 115 citations

Nox1 Redox Signaling Mediates Oncogenic Ras-induced Disruption of Stress Fibers and Focal Adhesions by Down-regulating Rho

2007 • 107 citations

Expression of NADPH Oxidase Isoform 1 (Nox1) in Human Placenta: Involvement in Preeclampsia

2005 • 107 citations

NADPH oxidase 1 plays a critical mediating role in oncogenic Ras-induced vascular endothelial growth factor expression

2008 • 103 citations

Expression of Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase (ThoX, LNOX, Duox) Genes and Proteins in Human Thyroid Tissues¹

2001 • 100 citations

TLR-4 Signalling Accelerates Colon Cancer Cell Adhesion via NF-κB Mediated Transcriptional Up-Regulation of Nox-1

2012 • 98 citations

A Constitutive NADPH Oxidase-Like System Containing gp91phox Homologs in Human Keratinocytes

2004 • 91 citations

NADPH Oxidase 1 Overexpression Enhances Invasion via Matrix Metalloproteinase-2 and Epithelial–Mesenchymal Transition in Melanoma Cells

2012 • 88 citations

Expression of Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase (ThoX, LNOX, Duox) Genes and Proteins in Human Thyroid Tissues

2001 • 82 citations

NADPH oxidases 1 and 4 mediate cellular senescence induced by resveratrol in human endothelial cells

2009 • 80 citations

Beneficial Effects of Antioxidant Vitamins on the Stenotic Kidney

2003 • 77 citations

Urokinase Plasminogen Activator Stimulates Vascular Smooth Muscle Cell Proliferation Via Redox-Dependent Pathways

2006 • 70 citations

Kidney Fibrosis in Hypertensive Rats: Role of Oxidative Stress

2008 • 68 citations

Composition and Functions of Vascular Nicotinamide Adenine Dinucleotide Phosphate Oxidases

2008 • 66 citations

Nox1 regulates apoptosis and potentially stimulates branching morphogenesis in sinusoidal endothelial cells

2004 • 65 citations

Nox1 Oxidase Suppresses Influenza A Virus-Induced Lung Inflammation and Oxidative Stress

2013 • 65 citations

Regulation of growth and apoptosis of cultured guinea pig gastric mucosal cells by mitogenic oxidase 1

2000 • 62 citations

UVB Radiation Induces Apoptosis in Keratinocytes by Activating a Pathway Linked to “BLT2-Reactive Oxygen Species”

2010 • 56 citations

To prevent, protect and save the ischemic heart: antioxidants revisited

2009 • 54 citations

7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: Roles of NADPH oxidase, mitochondria, and lipid rafts

2006 • 53 citations

Overexpression of manganese superoxide dismutase suppresses increases in collagen accumulation induced by culture of mesangial cells in high-media glucose

2001 • 47 citations

Co-treatment with hepatocyte growth factor and TGF-β1 enhances migration of HaCaT cells through NADPH oxidase-dependent ROS generation

2010 • 46 citations

RETRACTED: REDOX regulation of IL-13 signaling in intestinal epithelial cells: Usage of alternate pathways mediates distinct gene expression patterns

2010 • 45 citations

Role of Nicotinamide Adenine Dinucleotide Phosphate–Reduced Oxidase Proteins in Pseudomonas aeruginosa–Induced Lung Inflammation and Permeability

2013 • 43 citations

NADPH Oxidase 1 Controls the Persistence of Directed Cell Migration by a Rho-Dependent Switch of α2/α3 Integrins

2009 • 35 citations

Regulation of NOX-1 expression in beta cells: A positive feedback loop involving the Src-kinase signaling pathway

2013 • 30 citations

Whole-cell and nuclear NADPH oxidases levels and distribution in human endocardial endothelial, vascular smooth muscle, and vascular endothelial cells

2012 • 29 citations

Growth factors: the wound healing therapy of the future?

2003 • 26 citations

Mouse embryonic fibroblasts from CD38 knockout mice are resistant to oxidative stresses through inhibition of reactive oxygen species production and Ca2+ overload

2010 • 25 citations

NADPH oxidase expression and production of superoxide by human corneal stromal cells.

2009 • 24 citations

Neuregulin induces HaCaT keratinocyte migration via Rac1‐mediated NADPH‐oxidase activation

2011 • 20 citations

Nox1 Induces Differentiation Resistance in Immortalized Human Keratinocytes Generating Cells that Express Simple Epithelial Keratins

2007 • 14 citations

NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes

2013 • 13 citations