Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Interleukin-6: An Overview

1990 • 1,910 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

1990 • 1,377 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)

1990 • 1,307 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

Biological and clinical aspects of interleukin 6

1990 • 1,091 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Homeo Boxes in the Study of Development

1987 • 905 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention.

1992 • 731 citations

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

1987 • 699 citations

‘Zinc fingers’: a novel protein motif for nucleic acid recognition

1987 • 676 citations

Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines.

1990 • 642 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to CEBP

1990 • 637 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

1990 • 599 citations

Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.

1989 • 587 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells.

1989 • 488 citations

Dorsal , an Embryonic Polarity Gene in Drosophila , Is Homologous to the Vertebrate Proto-Oncogene, c- rel

1987 • 485 citations

New procedure for DNA transfection with polycation and dimethyl sulfoxide.

1984 • 481 citations

Isolation of a rel -related Human cDNAThat Potentially Encodes the 65-kD Subunit of NF-κB

1991 • 448 citations

Functional antagonism between c-Jun and MyoD proteins: A direct physical association

1992 • 424 citations

NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats

1992 • 415 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription.

1991 • 388 citations

Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos

1992 • 348 citations

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

1990 • 330 citations

The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function

1990 • 325 citations

The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

1992 • 324 citations

Human and Drosophila Homeodomain Proteins That Enhance the DNA-Binding Activity of Serum Response Factor

1992 • 314 citations

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization

1991 • 312 citations

Reciprocal Regulation of Adipogenesis by Myc and C/EBPα

1992 • 296 citations

Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.

1990 • 290 citations

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression.

1992 • 288 citations

Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein.

1990 • 287 citations

Constitutive and interleukin-1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene.

1990 • 283 citations

Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family.

1990 • 274 citations

Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP.

1990 • 272 citations

NF-κB, KBF1, dorsal, and related matters

1990 • 267 citations

Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?

1989 • 266 citations

The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in drosophila

1991 • 229 citations

The role of the CCAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP).

1990 • 210 citations

A family of constitutive C/EBP-like DNA binding proteins attenuate the IL-1 alpha induced, NF kappa B mediated trans-activation of the angiotensinogen gene acute-phase response element.

1990 • 180 citations

Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative.

1992 • 177 citations

Interleukin 1 and cyclic AMP induce kappa immunoglobulin light-chain expression via activation of an NF-kappa B-like DNA-binding protein.

1989 • 176 citations

Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene.

1990 • 172 citations

Interleukin 6 induces a liver-specific nuclear protein that binds to the promoter of acute-phase genes.

1989 • 172 citations

Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts.

1991 • 167 citations

Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.

1989 • 164 citations

Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84).

1992 • 155 citations

Two distinct forms of active transcription factor CREB (cAMP response element binding protein).

1990 • 132 citations

Evidence of Changes in Protease Sensitivity and Subunit Exchange Rate on DNA Binding by C/EBP

1990 • 127 citations

v-rel oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells

1988 • 126 citations

HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises

1989 • 126 citations

Identification of a Naturally Occurring Transforming Variant of the p65 Subunit of NF-κB

1992 • 105 citations

Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter.

1990 • 85 citations

The helix-loop-helix protein rE12 and the C/EBP-related factor rNFIL-6 bind to neighboring sites within the c-fos serum response element.

1991 • 74 citations

The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation

1992 • 66 citations

Trans-dominant negative mutants of Fos and Jun.

1990 • 66 citations

Two purified factors bind to the same sequence in the enhancer of mouse MHC class I genes: one of them is a positive regulator induced upon differentiation of teratocarcinoma cells

1989 • 65 citations

Developmentally regulated interactions of liver nuclear factors with the rat phosphoenolpyruvate carboxykinase promoter.

1990 • 43 citations

Basic peptides enhance protein/ DNA interactionin vitro

1992 • 17 citations

Deleted Work

1955 • 0 citations