B-Cell Coactivator OBF-1 Exhibits Unusual Transcriptional Properties and Functions in a DNA-Bound Oct-1-Dependent Fashion

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 1,001 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 653 citations

The Enhanceosome and Transcriptional Synergy

1998 • 545 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

POU domain family values: flexibility, partnerships, and developmental codes.

1997 • 481 citations

POU-domain transcription factors: pou-er-ful developmental regulators.

1991 • 461 citations

Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure.

1995 • 416 citations

The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.

1995 • 391 citations

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

1995 • 374 citations

Octamania: The POU factors in murine development

1991 • 373 citations

A B-cell coactivator of octamer-binding transcription factors

1995 • 301 citations

Transcription mechanisms and regulation

1994 • 299 citations

B-cell-specif ic coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation

1996 • 284 citations

Cloning, Functional Characterization, and Mechanism of Action of the B-Cell-Specific Transcriptional Coactivator OCA-B

1995 • 273 citations

Three Functional Classes of Transcriptional Activation Domains

1996 • 267 citations

The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes

1996 • 240 citations

Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding protein.

1988 • 236 citations

Synergism in transcriptional activation: a kinetic view.

1993 • 196 citations

A simple and highly efficient procedure for rescuing autonomous plasmids from yeast

1992 • 196 citations

Transcription : mechanisms and regulation

1994 • 195 citations

Activator-induced conformational change in general transcription factor TFIIB

1994 • 177 citations

Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo

1995 • 161 citations

Chromatin Structure and RNA Polymerase II Connection: Implications for Transcription

1996 • 159 citations

B lymphocytes are impaired in mice lacking the transcriptional co‐activator Bob1/OCA‐B/OBF1

1996 • 139 citations

The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation.

1996 • 138 citations

Assembly of the isomerized TFIIA--TFIID--TATA ternary complex is necessary and sufficient for gene activation.

1996 • 136 citations

Identification of transcriptional activation and inhibitory domains in serum response factor (SRF) by using GAL4-SRF constructs.

1993 • 120 citations

Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain.

1996 • 118 citations

Functional distinctions between yeast TATA elements.

1989 • 111 citations

Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities.

1991 • 99 citations

The Carboxy-Terminal Transactivation Domain of Oct-4 Acquires Cell Specificity through the POU Domain

1997 • 99 citations

Rapid test forin vivostability and DNA binding of mutated octamer binding proteins with ‘mini extracts’, prepared from a transfected cells

1989 • 91 citations

The Large Subunit of Basal Transcription Factor SNAP_c Is a Myb Domain Protein That Interacts with Oct-1

1998 • 90 citations

Sequence-specific DNA binding of the B-cell-specific coactivator OCA-B.

1996 • 89 citations

Combinatorial regulation of transcription I: General aspects of transcriptional control

1995 • 86 citations

Inducible Expression and Phosphorylation of Coactivator BOB.1/OBF.1 in T Cells

1997 • 86 citations

Synergistic and promoter-selective activation of transcription by recruitment of transcription factors TFIID and TFIIB

1997 • 73 citations

Transcription: basal factors and activation

1996 • 69 citations

Coactivator OBF-1 Makes Selective Contacts with Both the POU-Specific Domain and the POU Homeodomain and Acts as a Molecular Clamp on DNA

1998 • 69 citations

Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription

1997 • 64 citations

Functional Characterization of the Murine Homolog of the B cell-specific Coactivator BOB.1/OBF.1

1995 • 59 citations

The Oct-1 POU domain activates snRNA gene transcription by contacting a region in the SNAP_c largest subunit that bears sequence similarities to the Oct-1 coactivator OBF-1

1998 • 55 citations

OCA-B Is a Functional Analog of VP16 but Targets a Separate Surface of the Oct-1 POU Domain

1997 • 51 citations

Coactivation by OCA-B: Definition of Critical Regions and Synergism with General Cofactors

1998 • 45 citations