Transcription: basal factors and activation

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

Crystal structure of a yeast TBP/TATA-box complex

1993 • 1,082 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Co-crystal structure of TBP recognizing the minor groove of a TATA element

1993 • 1,039 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

RNA POLYMERASE II

1991 • 729 citations

DNA sequence requirements for transcriptional initiator activity in mammalian cells

1994 • 625 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

1995 • 546 citations

Crystal structure of a TFIIB–TBP–TATA-element ternary complex

1995 • 542 citations

Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

1994 • 473 citations

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast

1993 • 465 citations

COMMON THEMES IN ASSEMBLY AND FUNCTION OF EUKARYOTIC TRANSCRIPTION COMPLEXES

1995 • 434 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1994 • 432 citations

Cdk-activating kinase complex is a component of human transcription factor TFIIH

1995 • 431 citations

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

1994 • 426 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II

1994 • 358 citations

DNA sequence requirements for transcriptional initiator activity in mammalian cells.

1994 • 340 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

Recycling of the general transcription factors during RNA polymerase II transcription.

1995 • 309 citations

The RNA polymerase II holoenzyme and its implications for gene regulation

1995 • 297 citations

Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

1994 • 294 citations

Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II

1995 • 290 citations

Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome

1995 • 280 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

General requirement for RNA polymerase II holoenzymes in vivo.

1995 • 249 citations

Transcription: In tune with the histones

1994 • 239 citations

Association of an activator with an RNA polymerase II holoenzyme.

1995 • 237 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

Drosophila TAF _II 150: Similarity to Yeast Gene TSM-1 and Specific Binding to Core Promoter DNA

1994 • 212 citations

KIN28 Encodes a C-Terminal Domain Kinase That Controls mRNA Transcription in Saccharomyces cerevisiae but Lacks Cyclin-Dependent Kinase-Activating Kinase (CAK) Activity

1995 • 208 citations

A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation.

1994 • 207 citations

A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation

1995 • 194 citations

Requirement for TFIIH kinase activity in transcription by RNA polymerase II

1995 • 189 citations

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain

1995 • 188 citations

A general mechanism for transcriptional synergy by eukaryotic activators

1995 • 185 citations

TheKIN28Gene is Required both for RNA Polymerase II Mediated Transcription and Phosphorylation of the Rpb1p CTD

1995 • 185 citations

Activator-induced conformational change in general transcription factor TFIIB

1994 • 177 citations

A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID

1992 • 170 citations

Yeast TAF IIS in a multisubunit complex required for activated transcription

1994 • 163 citations

Promoter-Selective Transcriptional Defect in Cell Cycle Mutant ts13 Rescued by hTAF _II 250

1994 • 163 citations

Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo

1995 • 161 citations

An ATP-dependent inhibitor of TBP binding to DNA.

1993 • 156 citations

RNA polymerase II C-terminal domain required for enhancer-driven transcription

1995 • 155 citations

Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcription.

1994 • 151 citations

The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA.

1995 • 143 citations

Activation of the TFIID-TFIIA complex with HMG-2.

1995 • 139 citations

The TBP-TFIIA Interaction in the Response to Acidic Activators in Vivo

1995 • 132 citations

Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.

1995 • 126 citations

Solution structure of the c-terminal core domain of human TFIIB: Similarity to cyclin A and interaction with TATA-binding protein

1995 • 120 citations

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

1994 • 116 citations

Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation.

1994 • 114 citations

The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation.

1995 • 113 citations

Regulation of transcriptional elongation by RNA polymerase II

1995 • 111 citations

Initiation of transcription by RNA polymerase II is limited by melting of the promoter DNA in the region immediately upstream of the initiation site.

1994 • 110 citations

Effects of activation-defective TBP mutations on transcription initiation in yeast

1994 • 110 citations

Recruiting TATA-Binding Protein to a Promoter: Transcriptional Activation without an Upstream Activator

1995 • 108 citations

Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation.

1994 • 103 citations

Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID.

1993 • 97 citations

Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex.

1996 • 97 citations

Model for binding of transcription factor TFIIB to the TBP-DNA complex

1995 • 97 citations

Analysis of the Yeast Transcription Factor TFIIA: Distinct Functional Regions and a Polymerase II-Specific Role in Basal and Activated Transcription

1995 • 95 citations

Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor

1995 • 89 citations

News on initiation and elongation of transcription by RNA polymerase II

1995 • 88 citations

The multifunctional TFIIH complex and transcriptional control

1994 • 88 citations

TBP mutants defective in activated transcription in vivo.

1995 • 87 citations

Interaction between a transcriptional activator and transcription factor IIB in vivo

1993 • 80 citations

Role of core promoter structure in assembly of the RNA polymerase II preinitiation complex. A common pathway for formation of preinitiation intermediates at many TATA and TATA-less promoters

1994 • 73 citations

Topological localization of the human transcription factors IIA, IIB, TATA box-binding protein, and RNA polymerase II-associated protein 30 on a class II promoter.

1994 • 63 citations

A heteroduplex template circumvents the energetic requirement for ATP during activated transcription by RNA polymerase II

1994 • 61 citations

Mutations on the DNA-Binding Surface of TATA-Binding Protein Can Specifically Impair the Response to Acidic Activators In Vivo

1995 • 58 citations

Binding of TFIID to the CYC1 TATA boxes in yeast occurs independently of upstream activating sequences.

1994 • 53 citations

Protease footprinting reveals a surface on transcription factor TFIIB that serves as an interface for activators and coactivators.

1995 • 37 citations

Clamping the TBP stirrup

1995 • 4 citations

Mimicry with gold

1995 • 3 citations