HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

1982 • 877 citations

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1984 • 858 citations

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells

1985 • 613 citations

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor

1988 • 607 citations

Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

1989 • 590 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.

1987 • 565 citations

Long-Term Cultures of HTLV-III—Infected T Cells: a Model of Cytopathology of T-Cell Depletion in AIDS

1986 • 537 citations

Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.

1986 • 519 citations

Interleukin 2

1984 • 497 citations

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses.

1987 • 490 citations

HTLV-I Tax Induces Cellular Proteins that Activate the κB Element in the IL-2 Receptor α Gene

1988 • 480 citations

Activation of the HIV-1 LTR by T Cell Mitogens and the Trans-Activator Protein of HTLV-I

1987 • 460 citations

Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering

1987 • 438 citations

The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV

1988 • 427 citations

Regulation of the human interleukin-2 receptor α chain promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I

1987 • 423 citations

The interleukin 2 receptor. Functional consequences of its bimolecular structure.

1987 • 409 citations

Human cutaneous T cell lymphoma and leukemia cell lines produce and respond to T cell growth factor

1981 • 340 citations

Cellular Transcription Factors and Regulation of IL-2 Receptor Gene Expression by HTLV-I tax Gene Product

1988 • 327 citations

Kappa B-Specific DNA Binding Proteins: Role in the Regulation of Human Interleukin-2 Gene Expression

1989 • 327 citations

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1987 • 306 citations

Induction of HTLV-III/LAV from a Nonvirus-Producing T-Cell Line: Implications for Latency

1986 • 264 citations

Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells.

1985 • 237 citations

Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor.

1987 • 234 citations

Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen.

1984 • 227 citations

Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor.

1984 • 224 citations

Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells.

1984 • 192 citations

Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein.

1987 • 179 citations

Characterization of cellular proteins recognizing the HIV enhancer using a microscale DNA-affinity precipitation assay

1987 • 176 citations

Phorbol ester enhances human immunodeficiency virus-promoted gene expression and acts on a repeated 10-base-pair functional enhancer element.

1987 • 164 citations

Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor.

1987 • 147 citations

Interleukin 1-dependent induction of both interleukin 2 secretion and interleukin 2 receptor expression by thymoma cells.

1986 • 133 citations

Recent Advances in the Molecular Biology of HTLV-1: Trans-Activation of Viral and Cellular Genes

1987 • 104 citations

Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins.

1989 • 98 citations

Autocrine growth of interleukin 2-producing leukemic cells in a patient with adult T cell leukemia

1986 • 98 citations

Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins

1989 • 92 citations

Molecular Analysis of the Interleukin‐2 System

1986 • 89 citations

Expression of functional interleukin-2 receptors in human light chain/Tac ransgenic mice

1988 • 70 citations

Induction of interleukin 2 receptor (TAC) by tumor necrosis factor in YT cells.

1987 • 69 citations

Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation.

1988 • 68 citations

The ‘CC.Ar.GG’ box

1988 • 65 citations

Co-internalization of the p55 and p70 subunits of the high-affinity human interleukin 2 receptor. Evidence for a stable ternary receptor complex.

1988 • 35 citations

Induction of Interleukin-2 Receptor-α Gene Expression Is Regulated by Post-translational Activation of κ B Specific DNA Binding Proteins

1989 • 32 citations