Hepatitis C: progress and problems

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis

1989 • 3,401 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Genetic organization and diversity of the hepatitis C virus.

1991 • 1,717 citations

Detection of Antibody to Hepatitis C Virus in Prospectively Followed Transfusion Recipients with Acute and Chronic Non-A, Non-B Hepatitis

1989 • 1,698 citations

Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa

1989 • 1,658 citations

The Natural History of Community-Acquired Hepatitis C in the United States

1992 • 1,614 citations

Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region

1993 • 1,401 citations

A Role for Hepatitis C Virus Infection in Type II Cryoglobulinemia

1992 • 1,302 citations

Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus

1990 • 1,236 citations

Recombinant Interferon Alfa Therapy for Chronic Hepatitis C

1989 • 1,233 citations

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

1990 • 1,208 citations

Risk Factors for Hepatocellular Carcinoma among Patients with Chronic Liver Disease

1993 • 1,118 citations

Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution

1992 • 938 citations

Membranoproliferative Glomerulonephritis Associated with Hepatitis C Virus Infection

1993 • 894 citations

Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease

1991 • 854 citations

Significance of serum hepatitis C virus RNA levels in chronic hepatitis C

1993 • 822 citations

Lack of Protective Immunity Against Reinfection with Hepatitis C Virus

1992 • 760 citations

Detection of hepatitis C viral sequences in non-A, non-B hepatitis

1990 • 732 citations

The Declining Risk of Post-Transfusion Hepatitis C Virus Infection

1992 • 727 citations

Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

1992 • 712 citations

Long-Term Mortality after Transfusion-Associated Non-A, Non-B Hepatitis

1992 • 692 citations

Detection of hepatitis C virus by polymerase chain reaction and response to interferon-α therapy: Relationship to genotypes of hepatitis C virus

1992 • 689 citations

Transmission of Hepatitis C Virus from Mothers to Infants

1994 • 682 citations

Transfusion-Associated Hepatitis Not Due to Viral Hepatitis Type A or B

1975 • 657 citations

Nucleotide sequence and mutation rate of the H strain of hepatitis C virus.

1991 • 609 citations

Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites

1993 • 601 citations

Risk Factors for Acute Non-A, Non-B Hepatitis in the United States and Association With Hepatitis C Virus Infection

1990 • 597 citations

Interferon Alfa-2a Therapy in Cryoglobulinemia Associated with Hepatitis C Virus

1994 • 589 citations

Vaccination of chimpanzees against infection by thehepatitis C virus.

1994 • 572 citations

Detection of hepatitis C viral sequences in blood donations by "nested" polymerase chain reaction and prediction of infectivity

1990 • 569 citations

Long-term clinical and histopathological follow-up of chronic posttransfusion hepatitis

1991 • 542 citations

The Pathology of Hepatitis C

1992 • 539 citations

Hepatitis C Virus Infection in Post-Transfusion Hepatitis

1991 • 538 citations

Hepatitis C Virus Infection in Patients with Essential Mixed Cryoglobulinemia

1992 • 535 citations

Recurrent and acquired hepatitis C viral infection in liver transplant recipients

1992 • 511 citations

Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay

1991 • 509 citations

The histological features of chronic hepatitis C and autoimmune chronic hepatitis: A comparative analysis

1992 • 498 citations

Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus

1993 • 476 citations

Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis.

1992 • 465 citations

LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase.

1991 • 455 citations

NS3 is a serine protease required for processing of hepatitis C virus polyprotein

1993 • 454 citations

Factors predictive of response to interferon-α therapy in hepatitis C virus infection

1994 • 444 citations

Infection of peripheral mononuclear blood cells by hepatitis C virus

1992 • 442 citations

Hepatitis C virus antibodies in chronic active hepatitis: pathogenetic factor or false-positive result?

1990 • 429 citations

Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end.

1991 • 426 citations

Hepatitis C virus infection in medical personnel after needlestick accident

1992 • 425 citations

Importance of Heterosexual Activity in the Transmission of Hepatitis B and Non-A, Non-B Hepatitis

1989 • 422 citations

At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide.

1993 • 421 citations

A second hepatitis C virus-encoded proteinase.

1993 • 416 citations

LONG-INCUBATION POST-TRANSFUSION HEPATITIS WITHOUT SEROLOGICAL EVIDENCE OF EXPOSURE TO HEPATITIS-B VIRUS

1974 • 414 citations

Biosynthesis and biochemical properties of the hepatitis C virus core protein

1994 • 413 citations

Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses

1994 • 411 citations

Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins

1994 • 411 citations

Sequence analysis of the 5' noncoding region of hepatitis C virus.

1992 • 410 citations

Reliability of polymerase chain reaction for detection of hepatitis C virus

1993 • 403 citations

Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: Variability and stability

1992 • 384 citations

Decrease in Serum Hepatitis C Viral RNA during Alpha-Interferon Therapy for Chronic Hepatitis C

1991 • 383 citations

Transmission of Hepatitis C Virus by Organ Transplantation

1991 • 382 citations

Quantitative analysis of hepatitis C virus RNA in serum during interferon alfa therapy

1993 • 381 citations

Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus

1993 • 374 citations

Pathological diagnosis of chronic hepatitis C: A multicenter comparative study with chronic hepatitis B

1993 • 373 citations

Hepatitis C Virus Infection as a Risk Factor for Hepatocellular Carcinoma in Patients with Cirrhosis

1992 • 361 citations

Hepatitis C in Hospital Employees with Needlestick Injuries

1991 • 343 citations

Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells

1993 • 333 citations

Sensitivity, specificity, and predictability of biopsy interpretations in chronic hepatitis

1993 • 315 citations

Heterosexual Co-transmission of Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV)

1991 • 312 citations

Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes

1993 • 310 citations

ANTI-HEPATITIS C ANTIBODIES AND NON-A, NON-B POST-TRANSFUSION HEPATITIS IN THE NETHERLANDS

1989 • 308 citations

Detection of three types of hepatitis C virus in blood donors: investigation of type‐specific differences in serologic reactivity and rate of alanine aminotransferase abnormalities

1993 • 299 citations

Hepatitis C virus and porphyria cutanea tarda: Evidence of a strong association

1992 • 298 citations

The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients

1992 • 295 citations

Quantitation of hepatitis C virus RNA in liver transplant recipients

1994 • 291 citations

A pilot study of ribavirin therapy for chronic hepatitis C

1992 • 291 citations

Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV

1993 • 290 citations

Interferon-alpha in mixed cryoglobulinemia patients: a randomized, crossover-controlled trial

1993 • 285 citations

Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children

1994 • 283 citations

Identification of Genotypes of Hepatitis C Virus by Sequence Comparisons in the Core, E1 and NS-5 Regions

1994 • 283 citations

Type 2 autoimmune hepatitis and hepatitis C virus infection

1990 • 281 citations

Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay.

1992 • 275 citations

Vertical transmission of hepatitis C virus

1991 • 274 citations

Hepatitis B and Hepatitis C in Emergency Department Patients

1992 • 274 citations

Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis

1992 • 270 citations

Reinfection of liver graft by hepatitis C virus after liver transplantation.

1992 • 265 citations

Prevalence of Hepatitis C Virus RNA in Organ Donors Positive for Hepatitis C Antibody and in the Recipients of Their Organs

1992 • 260 citations

Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV): use of type-specific peptides to serologically differentiate infections with HCV types 1, 2, and 3

1993 • 259 citations

Quantification of hepatitis C virus by competitive reverse transcription—polymerase chain reaction: Increase of the virus in advanced liver disease

1993 • 257 citations

Risk for Non-A, Non-B (Type C) Hepatitis through Sexual or Household Contact with Chronic Carriers

1990 • 247 citations

Hepatitis C antibody and chronic liver disease in haemophilia

1990 • 246 citations

The significance of antibody to hepatitis C virus in patients with chronic hepatitis B

1991 • 243 citations

Clinical and virological profiles in patients with multiple hepatitis virus infections

1993 • 242 citations

Hepatitis C virus antibodies in chronic alcoholic patients: Association with severity of liver injury

1990 • 241 citations

Peripheral blood leukocytes serve as a possible extrahepatic site for hepatitis C virus replication

1993 • 240 citations

Non-A, Non-B Post-Transfusion Hepatitis: Looking Back in the Second Decade

1993 • 239 citations

T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections

1994 • 239 citations

High prevalence of thyroid autoantibodies in a prospective series of patients with chronic hepatitis C before interferon therapy

1993 • 237 citations

Quantitative evaluation of hepatitis C virus RNA in patients with concurrent human immunodeficiency virus infections

1993 • 236 citations

Rapidly progressive non-A, non-B hepatitis in patients with human immunodeficiency virus infection

1989 • 235 citations

Genotypes and titers of hepatitis C virus for predicting response to interferon in patients with chronic hepatitis C

1994 • 234 citations

Sexual transmission of hepatitis C virus

1993 • 234 citations

Hepatitis C virus RNA and hepatitis B virus DNA in serum and liver of patients with fulminant hepatitis

1993 • 229 citations

Liver/kidney microsome antibody type 1 and hepatitis C virus infection

1992 • 226 citations

Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses

1993 • 220 citations

Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome

1993 • 219 citations

Response to interferon α therapy is influenced by the iron content of the liver

1994 • 216 citations

Hepatitis C viremia in chronic liver disease: Relationship to interferon-α or corticosteroid treatment

1994 • 215 citations

NON-A, NON-B HEPATITIS OCCURRING IN AGAMMAGLOBULINAEMIC PATIENTS AFTER INTRAVENOUS IMMUNOGLOBULIN

1984 • 214 citations

Detection of hepatitis C virus RNA in serum of patients with chronic hepatitis C treated with interferon-α

1992 • 212 citations

Posttransfusion Non-A, Non-B Hepatitis: Physicochemical Properties of Two Distinct Agents

1983 • 211 citations

Association between hepatitis C virus and mixed cryoglobulinemia [see comment].

1991 • 209 citations

Detection of replicative intermediates of hepatitis C viral RNA in liver and serum of patients with chronic hepatitis C.

1991 • 207 citations

Incidence and risk factors for hepatitis C seroconversion in hemodialysis: A prospective study

1993 • 206 citations

Antibodies to hepatitis C virus in autoimmune liver disease: evidence for geographical heterogeneity

1991 • 205 citations

Effect of screening for hepatitis C virus antibody and hepatitis B virus core antibody on incidence of post-transfusion hepatitis

1991 • 196 citations

Antibodies to hepatitis B virus and hepatitis C virus in alcoholic hepatitis and cirrhosis: Their prevalence and clinical relevance

1991 • 194 citations

Prevalence of hepatitis C virus antibody in a cohort of hemophilia patients [see comments]

1990 • 194 citations

Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: definition of optimal conditions for specimen collection and clinical application in interferon-treated patients.

1994 • 193 citations

Is hepatitis C virus infection a trigger of porphyria cutanea tarda?

1993 • 193 citations

Resolution of acute hepatitis C after therapy with natural beta interferon

1991 • 190 citations

Anti-GOR and hepatitis C virus in autoimmune liver diseases

1992 • 189 citations

Prevalence of Hepatitis C Virus Infection in Hemodialysis Patients: A Longitudinal Study Comparing the Results of RNA and Antibody Assays

1993 • 189 citations

Long-term follow-up of patients with chronic hepatitis C treated with α-interferon

1992 • 186 citations

A Structurally Flexible and Antigenically Variable N-Terminal Domain of the Hepatitis C Virus E2/NS1 Protein: Implication for an Escape from Antibody

1993 • 186 citations

The nomenclature of chronic active hepatitis: An obituary

1993 • 186 citations

The impact of hepatitis C virus infection on renal allograft recipients

1994 • 185 citations

Quantitation of hepatitis C virus RNA in serum of asymptomatic blood donors and patients with type C chronic liver disease

1993 • 185 citations

Detection of Replicative Form of Hepatitis C Virus RNA in Peripheral Blood Mononuclear Cells

1992 • 184 citations

The Hepatitis C Virus Encodes a Serine Protease Involved in Processing of the Putative Nonstructural Proteins from the Viral Polyprotein Precursor

1993 • 183 citations

Hepatitis C Virus Is Detected in a Monocyte/Macrophage Subpopulation of Peripheral Blood Mononuclear Cells of Infected Patients

1992 • 183 citations

Effect of interferon administration on serum hepatitis C virus RNA in patients with chronic hepatitis C

1991 • 180 citations

Occupational risk for hepatitis C virus infection among New York City dentists

1991 • 178 citations

Hepatitis C Virus Infection in Spouses of Patients with Type C Chronic Liver Disease

1994 • 176 citations

Mother-to-Infant Transmission of Hepatitis C Virus

1992 • 173 citations

Short-term prednisone therapy affects aminotransferase activity and hepatitis C virus RNA levels in chronic hepatitis C

1994 • 173 citations

High Prevalence of Hepatitis C Virus (HCV) RNA in Dialysis Patients: Failure of Commercially Available Antibody Tests to Identify a Significant Number of Patients with HCV Infection

1993 • 170 citations

Increased detection of hepatitis C virus (HCV)‐infected blood donors by a multiple‐antigen HCV enzyme immunoassay

1992 • 166 citations

Comparative efficacy of interferon alfa in cirrhotic and noncirrhotic patients with non-A, non-B, C hepatitis

1994 • 166 citations

Long-term follow-up of patients with chronic hepatitis C treated with different doses of interferon-alpha 2b.

1993 • 165 citations

Sequence analysis of the 5' nincoding region of hepatitis C virus

1992 • 165 citations

Early events in hepatitis C virus infection of chimpanzees.

1990 • 165 citations

Detection, semiquantitation, and genetic variation in hepatitis C virus sequences amplified from the plasma of blood donors with elevated alanine aminotransferase.

1990 • 162 citations

High sustained response rate and clearance of viremia in chronic hepatitis C after treatment with interferon-α2b for 60 weeks

1994 • 160 citations

Transmission of hepatitis C in an isolated area in Japan: Community-acquired infection

1994 • 159 citations

Possible Role of High-Titer Maternal Viremia in Perinatal Transmission of Hepatitis C Virus

1994 • 159 citations

Failure to detect hepatitis C virus genome in human secretions with the polymerase chain reaction

1991 • 159 citations

Association between hepatitis C virus and mixed cryoglobulinemia

1991 • 157 citations

Intravenous immunoglobulin prophylaxis causing liver damage in 16 of 77 patients with hypogammaglobulinemia or IgG subclass deficiency

1988 • 156 citations

Infrequent Vertical Transmission of Hepatitis C Virus

1993 • 156 citations

Antibody to hepatitis C virus increases with time on hemodialysis.

1992 • 156 citations

Hepatitis C virus antibodies and liver disease in patients with porphyria cutanea tarda

1993 • 155 citations

Sensitivity of serological assays to identify blood donors with hepatitis C viraemia

1992 • 154 citations

Mother-to-Child Transmission of Hepatitis C Virus Detected by Nested Polymerase Chain Reaction

1992 • 154 citations

Autoimmune Chronic Hepatitis Exacerbated by Alpha-Interferon

1992 • 153 citations

Hepatitis C virus antigen in hepatocytes: Immunomorphologic detection and identification

1992 • 153 citations

An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans

1994 • 152 citations

Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology.

1992 • 152 citations

Sexual transmission of hepatitis C virus: cohort study (1981-9) among European homosexual men.

1990 • 150 citations

Quantitation and typing of serum hepatitis C virus RNA in patients with chronic hepatitis C treated with interferon-β

1993 • 149 citations

Role of Hepatitis C Virus Infection in Spontaneous Hepatitis B Surface Antigen Clearance during Chronic Hepatitis B Virus Infection

1992 • 148 citations

Failure To Detect Vertical Transmission of Hepatitis C Virus

1992 • 147 citations

Interferon-alpha 2b therapy reduces liver fibrosis in chronic non-A, non-B hepatitis: a quantitative histological evaluation.

1993 • 147 citations

Intrafamilial Transmission of Hepatitis C Virus: The Important Role of Infections between Spouses

1992 • 147 citations

Improved detection of hepatitis c virus antibodies in high-risk populations

1992 • 145 citations

A unique, predominant hepatitis C virus variant found in an infant born to a mother with multiple variants

1993 • 145 citations

Effect of concurrent acute infection with hepatitis C virus on acute hepatitis B virus infection.

1993 • 144 citations

Fulminant or subfulminant non-A, non-B viral hepatitis: The role of hepatitis C and E viruses

1993 • 144 citations

Hypervariable region of hepatitis C virus envelope glycoprotein (E2/NS1) in an agammaglobulinemic patient

1994 • 143 citations

Hepatitis C Virus Not Found in Fulminant Non-A, Non-B Hepatitis

1991 • 143 citations

Interferon-α for chronic hepatitis C: An analysis of pretreatment clinical predictors of response

1994 • 142 citations

Antibody response to core, envelope and nonstructural hepatitis C virus antigens: Comparison of immunocompetent and immunosuppressed patients

1993 • 142 citations

Use of a signature nucleotide sequence of hepatitis C virus for detection of viral RNA in human serum and plasma

1991 • 141 citations

Absence of hepatitis C viral RNA from saliva and semen of patients with chronic hepatitis C

1992 • 140 citations

Predicting interferon therapy efficacy from hepatitis C virus genotype and RNA titer

1994 • 140 citations

A multicenter study of viral hepatitis in a United States hemophilic population

1993 • 139 citations

Rapid sequence variation of the hypervariable region of hepatitis C virus during the course of chronic infection

1993 • 138 citations

Viral pathogenesis of hepatocellular carcinoma in the United States

1993 • 135 citations

Tattooing as a risk of hepatitis C virus infection

1992 • 135 citations

Effects of anticoagulants and storage of blood samples on efficacy of the polymerase chain reaction assay for hepatitis C virus

1992 • 134 citations

Hepatitis C virus RNA in anti-HCV positive hemodialyzed patients: Significance and therapeutic implications

1993 • 134 citations

Storage conditions of blood samples and primer selection affect the yield of cDNA polymerase chain reaction products of hepatitis C virus

1992 • 134 citations

Discrepancy between biochemical and virological responses to interferon-$alpha; in chronic hepatitis C

1993 • 133 citations

A pilot study of ribavirin and interferon beta for the treatment of chronic hepatitis C

1993 • 131 citations

Loss of antibodies against hepatitis C virus in HIV-seropositive intravenous drug users

1990 • 128 citations

Production of Nonstructural Proteins of Hepatitis C Virus Requires a Putative Viral Protease Encoded by NS3

1994 • 128 citations

Identification of an immunodominant epitope within the capsid protein of hepatitis C virus.

1991 • 127 citations

Detection of the minus strand of hepatitis C virus RNA by reverse transcription and polymerase chain reaction: Implications for hepatitis C virus replication in infected tissue

1992 • 127 citations

Hepatitis C virus reinfection in allografts after orthotopic liver transplantation

1992 • 127 citations

Immunohistochemical Detection of Hepatitis C Virus-Infected Hepatocytes in Chronic Liver Disease With Monoclonal Antibodies to Core, Envelope and Ns3 Regions of the Hepatitis C Virus Genome

1992 • 125 citations

Multiple viral infection as the most common cause of fulminant and subfulminant viral hepatitis in an area endemic for hepatitis B: Application and limitations of the polymerase chain reaction

1994 • 125 citations

Lack of mother-to-infant transmission of hepatitis C virus in human immunodeficiency virus–seronegative women: A prospective study with hepatitis C virus RNA testing

1993 • 125 citations

Hepatitis C virus-specific CTL responses in the liver of chimpanzees with acute and chronic hepatitis C.

1993 • 124 citations

The role of hepatitis C virus in fulminant viral hepatitis in an area with endemic hepatitis A and B

1994 • 124 citations

Comparison of Risk Factors for Hepatitis C and Hepatitis B Virus Infection in Homosexual Men

1993 • 123 citations

NON-A, NON-B POST-TRANSFUSION HEPATITIS

1977 • 122 citations

HLA B44-restricted cytotoxic T lymphocytes recognizing an epitope on hepatitis C virus nucleocapsid protein

1993 • 121 citations

Viral and host factors that contribute to efficacy of interferon-α2a therapy in patients with chronic hepatitis C

1994 • 121 citations

Viral hepatitis in health care personnel at The Johns Hopkins Hospital. The seroprevalence of and risk factors for hepatitis B virus and hepatitis C virus infection.

1993 • 121 citations

Exacerbation of lichen planus during interferon alfa-2a therapy for chronic active hepatitis C

1993 • 119 citations

Hepatitis C Virus Infection Among Patients Attending a Clinic for Sexually Transmitted Diseases

1993 • 118 citations

Diagnosis of hepatitis C virus (HCV) infection using an immunodominant chimeric polyprotein to capture circulating antibodies: reevaluation of the role of HCV in liver disease.

1992 • 115 citations

Diagnosis of chronic hepatitis C after liver transplantation by the detection of viral sequences with polymerase chain reaction

1992 • 115 citations

Detection of genomic and intermediate replicative strands of hepatitis C virus in liver tissue by in situ hybridization.

1993 • 114 citations

Hepatitis C virus genotypes are not responsible for development of serious liver disease

1994 • 113 citations

Porphyria cutanea tarda and antibodies to hepatitis C virus

1993 • 113 citations

Analysis of Hepatitis C Virus Capsid, E1, and E2/NS1 Proteins Expressed in Insect Cells

1993 • 113 citations

Detection of hepatitis C virus antibodies and hepatitis C virus RNA in patients with alcoholic liver disease

1991 • 110 citations

Risk factors for hepatitis C virus infection in blood donors: a case‐control study

1992 • 109 citations

High Prevalence of Viral Infection in Adults with Homozygous and Heterozygous Alpha₁-Antitrypsin Deficiency and Chronic Liver Disease

1992 • 108 citations

Detection of Hepatitis C Virus Markers and Hepatitis C Virus Genomic—RNA After Needlestick Accidents

1993 • 108 citations

Seroepidemiology of hepatitis C virus infection in Taiwan

1991 • 107 citations

Long-term persistence of hepatitis C virus antibodies in a single source outbreak

1991 • 107 citations

Extraordinarily low density of hepatitis C virus estimated by sucrose density gradient centrifugation and the polymerase chain reaction

1992 • 106 citations

Treatment of chronic hepatitis C with high-dose interferon ?-2b

1993 • 106 citations

Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis

1993 • 105 citations

A multicenter randomized controlled trial of recombinant interferon-α2b in patients with acute transfusion-associated hepatitis C

1994 • 105 citations

Incidence, prevalence, and clinical course of hepatitis C following liver transplantation

1992 • 104 citations

Buoyant density of hepatitis C virus recovered from infected hosts: two different features in sucrose equilibrium density-gradient centrifugation related to degree of liver inflammation.

1994 • 104 citations

Etiological role of hepatitis E virus in sporadic fulminant hepatitis

1994 • 103 citations

Hepatitis C virus RNA and antibody response in the clinical course of acute hepatitis C virus infection

1992 • 102 citations

Hepatitis C virus RNA in blood donor sera detected by the polymerase chain reaction: Comparison with supplementary hepatitis C antibody assays

1991 • 101 citations

Acute exacerbation of liver disease during interferon alfa therapy for chronic hepatitis C

1992 • 101 citations

Hepatitis virus infection (HBV and HCV) in eleven Japanese hemodialysis units.

1992 • 99 citations

Detection of Hepatitis C Virus Antibody in the Absence of Viral RNA in Patients with Autoimmune Hepatitis

1992 • 99 citations

Detection of Chronic Hepatitis C Virus Infection by Four Diagnostic Systems: First–Generation and Second–Generation Enzyme–Linked Immunosorbent Assay, Second–Generation Recombinant Immunoblot Assay and Nested Polymerase Chain Reaction Analysis

1992 • 99 citations

Hepatitis C virus infection in kidney transplant recipients

1993 • 97 citations

Detection of Hepatitis C Virus Infection among Cadaver Organ Donors: Evidence for Low Transmission of Disease

1992 • 96 citations

Interferon-α in acute posttransfusion hepatitis C:. A randomized, controlled trial

1992 • 94 citations

N-Acetyl Cysteine Enhances the Response to Interferon-α in Chronic Hepatitis C: A Pilot Study

1993 • 94 citations

Analysis of hepatitis C virus genome in patients with autoimmune hepatitis type 2

1994 • 93 citations

A prospective study of hepatitis C virus infection among renal transplant recipients

1993 • 93 citations

The Natural History of Infection with Hepatitis C Virus (HCV) in Chimpanzees: Comparison of Serologic Responses Measured with First- and Second- Generation Assays and Relationship to HCV Viremia

1992 • 92 citations

Three different patterns of hepatitis C virus infection in chimpanzees

1992 • 92 citations

Risk of needle-stick injuries in the transmission of hepatitis C virus in hospital personnel

1992 • 92 citations

Aplastic anemia and viral hepatitis. Non-A, Non-B, Non-C?

1992 • 91 citations

Effect of α‐interferon therapy on hepatitis C viraemia in community‐acquired chronic non‐A, non‐B hepatitis: A quantitative polymerase chain reaction study

1991 • 91 citations

Partitioning of hepatitis C virus during Cohn‐Oncley fractionation of plasma

1992 • 90 citations

Clinical significance of concomitant hepatitis C infection in patients with alcoholic liver disease

1994 • 89 citations

Hepatitis C in Patients Undergoing Liver Transplantation

1991 • 89 citations

Hepatitis C viral RNA titers in serum prior to, during, and after oral treatment with ribavirin for chronic hepatitis C

1993 • 88 citations

Two Distinct Subtypes of Hepatitis C Virus Defined by Antibodies Directed to the Putative Core Protein

1992 • 87 citations

Management of Occupational Exposures to Bloodborne Pathogens: Hepatitis B Virus, Hepatitis C Virus, and Human Immunodeficiency Virus

1992 • 86 citations

Mixed Cryoglobulinemia in Chronic Hepatitis C Infection A Clinicopathologic Analysis of 10 Cases and Review of Recent Literature

1994 • 84 citations

p26 protein and 33-nm particle associated with nucleocapsid of hepatitis C virus recovered from the circulation of infected hosts

1992 • 83 citations

Hepatitis C viremia and anti-HCV antibodies in alcoholics

1992 • 82 citations

Prevalence of Anti‐HCV Antibody in Blood Donors in the Tokyo Area

1990 • 82 citations

Prediction of the response of chronic hepatitis C to interferon alfa: a statistical analysis of pretreatment variables.

1993 • 81 citations

Virological features of hepatitis C virus infection in hemodialysis patients

1993 • 81 citations

Prevalence of antibodies to hepatitis C virus among patients with cryptogenic chronic hepatitis and cirrhosis

1992 • 80 citations

Clinical and serological differentiation of autoimmune and hepatitis C virus-related chronic hepatitis

1993 • 80 citations

Temporal relationships of hepatitis C virus RNA and antibody responses following experimental infection of chimpanzees

1992 • 80 citations

Low risk of sexual transmission of hepatitis C virus

1993 • 77 citations

Hepatitis C virus RNA in saliva of patients with posttransfusion hepatitis and low efficiency of transmission among spouses

1992 • 77 citations

Hepatitis C and E in non-A non-B fulminant hepatic failure: a polymerase chain reaction and serological study

1994 • 76 citations

Hepatitis C viraemia in adults with type 2 autoimmune hepatitis

1991 • 76 citations

Liver damage in Italian patients with hereditary hemochromatosis is highly influenced by hepatitis B and C virus infection

1992 • 75 citations

Intrafamilial transmission of hepatitis C virus: The important role of inapparent transmission

1994 • 75 citations

Transmission of Non‐A, Non‐B Hepatitis by pH4‐Treated Intravenous Immunoglobulin

1989 • 74 citations

Contribution of hepatitis C virus to non-A, non-B fulminant hepatitis in Japan

1994 • 74 citations

Hepatic and extrahepatic HCV RNA strands in chronic hepatitis C: Different patterns of response to interferon treatment

1993 • 73 citations

Detection of hepatitis C virus RNA in chronic non-A, non-B liver disease

1992 • 73 citations

5′ end-dependent translation initiation of hepatitis C viral RNA and the presence of putative positive and negative translational control elements within the 5′ untranslated region

1992 • 73 citations

Low incidence of non-A, non-B post-transfusion hepatitis in London confirmed by hepatitis C virus serology

1991 • 71 citations

Hepatitis C Virus Replication during Acute Infection in the Chimpanzee

1992 • 70 citations

Detection of hepatitis C virus RNA in peripheral blood mononuclear cells and in saliva

1993 • 69 citations

Changes in hepatitis C virus antigen in liver with antiviral therapy

1993 • 69 citations

Treatment with interferon(s) of community-acquired chronic hepatitis and cirrhosis type C

1993 • 69 citations

Predictive Value of Screening Tests for Persistent Hepatitis C Virus Infection Evidenced by Viraemia: Japanese Experience

1993 • 68 citations

Risk of hepatitis C virus infections through household contact with chronic carriers: Analysis of nucleotide sequences

1993 • 67 citations

Detection of hepatitis C virus (HCV) RNA by PCR related to HCV antibodies in serum and liver histology in swedish blood donors

1993 • 66 citations

Sequence Variation in the Large Envelope Glycoprotein (E2jNSl) of Hepatitis C Virus during Chronic Infection

1993 • 66 citations

Hepatitis C virus replication in ‘autoimmune’ chronic hepatitis

1991 • 65 citations

Hepatitis C RNA in liver of chronic hepatitis C patients before and after interferon alfa treatment

1993 • 65 citations

Withdrawal of immunosuppressive therapy in allogeneic bone marrow transplantation reactivates chronic viral hepatitis C.

1991 • 65 citations

Sustained hypothyroidism induced by recombinant alpha interferon in patients with chronic hepatitis C.

1992 • 65 citations

Hepatitis C-Related Hepatocellular Carcinoma

1993 • 64 citations

Demonstration of hepatitis C virus genome in saliva and urine of patients with type C hepatitis: Usefulness of the single round polymerase chain reaction method for detection of the HCV genome

1993 • 64 citations

Prevalence of hepatitis C in tropical communities: The importance of confirmatory assays

1991 • 62 citations

Immunodominant regions within the hepatitis C virus core and putative matrix proteins

1992 • 62 citations

Predominant etiologic association of hepatitis C virus with hepatocellular carcinoma compared with hepatitis B virus in elderly patients in a hepatitis B‐endemic area

1993 • 61 citations

Transmission of Hepatitis C Virus From Mothers to Infants

1994 • 61 citations

HEPATITIS C IS A POOR PROGNOSTIC INDICATOR IN BLACK KIDNEY TRANSPLANT RECIPIENTS

1993 • 61 citations

Hepatitis C virus infection among sexually promiscuous groups and the heterosexual partners of hepatitis C virus infected index cases

1993 • 61 citations

Early Antihepatitis C Virus Response with Second—Generation C200/C22 ELISA

1992 • 58 citations

Multiple False-positive Serologic Tests for HIV, HTLV-1, and Hepatitis C Following Influenza Vaccination, 1991

1992 • 57 citations

The presence of hepatitis C virus (HCV) antibody in human immunodeficiency virus-positive hemophilic men undergoing HCV "seroreversion"

1993 • 57 citations

Patterns of antibodies to hepatitis C virus in patients with chronic non-A, non-B hepatitis and their relationship to viral replication and liver disease

1993 • 56 citations

Intravenous Drug Abuse–the Major Route of Hepatitis C Virus Transmission among Alcohol-Dependent Individuals?

1993 • 56 citations

Outcome of HCV infection after renal transplantation

1994 • 56 citations

Seroprevalence and risk factors for hepatitis C virus antibody in pregnant women.

1992 • 54 citations

Demonstration of Sugar Moiety on the Surface of Hepatitis C Virions Recovered from the Circulation of Infected Humans

1993 • 53 citations

Peripheral-blood mononuclear cell responses to recombinant hepatitis C virus antigens in patients with chronic hepatitis C

1993 • 52 citations

Incidence of Non-A, Non-B Hepatitis after Screening Blood Donors for Antibodies to Hepatitis C Virus and Surrogate Markers

1991 • 51 citations

Recombinant immunoblot assay reaction patterns and hepatitis C virus RNA in blood donors and non‐A, non‐B hepatitis patients

1993 • 51 citations

Polymerase chain reaction assay for hepatitis C virus RNA using a single tube for reverse transcription and serial rounds of amplification with nested primer pairs

1992 • 51 citations

Interaction of immune sera with synthetic peptides corresponding to the structural protein region of hepatitis C virus.

1992 • 51 citations

Significance of antibody to the host cellular gene derived epitope GOR in chronic hepatitis C virus infection

1993 • 50 citations

Hepatitis C Virus Antibody in Alcoholic Patients

1993 • 50 citations

Clinical, biochemical and histological features in 102 patients with chronic hepatitis C virus infection

1993 • 50 citations

Enhanced Sensitivity of a Second Generation ELISA for Antibody to Hepatitis C Virus

1992 • 50 citations

Hepatitis C Viraemia in United Kingdom Blood Donors: A Multicentre Study

1992 • 49 citations

Detection of hepatitis C virus RNA by nested polymerase chain reaction in sera of patients with chronic non-A, non-B hepatitis treated with interferon

1992 • 48 citations

Serum autoantibodies and the diagnosis of type-1 autoimmune hepatitis in Italy: a reappraisal at the light of hepatitis C virus infection.

1992 • 48 citations

Hepatitis C virus c100 antigen in liver tissue from patients with acute and chronic infection.

1993 • 47 citations

Search for intrafamilial transmission of hepatitis C virus in hemophilia patients

1993 • 47 citations

Overestimation of the prevalence of antibody to hepatitis C virus in retrospective studies on stored sera

1991 • 47 citations

Hepatitis C virus viremia following clinical resolution of acute hepatitis C

1994 • 47 citations

Peptide immunogen mimicry of putative E1 glycoprotein-specific epitopes in hepatitis C virus

1994 • 47 citations

Hepatitis C viremia in patients with hepatitis C virus infection

1992 • 46 citations

Detection of serum hepatitis C virus RNA in HCV antibody-seropositive volunteer blood donors

1993 • 45 citations

Confirmation of hepatitis C virus antibody in blood donors

1993 • 45 citations

Reactivation of chronic hepatitis C after withdrawal of immunosuppressive therapy

1993 • 44 citations

Prevalence of hepatitis C viral infection in a community in Taiwan

1993 • 44 citations

Is Hepatitis C Virus Involved in Hepatitis-Associated Aplastic Anemia?

1990 • 44 citations

Detection and quantification of hepatitis C virus RNA replication in the liver

1994 • 43 citations

Elevated Serum Alanine Aminotransferase Levels in Blood Donors: The Contribution of Hepatitis C Virus

1991 • 43 citations

Detection of hepatitis C virus sequences in sera with controversial serology by nested polymerase chain reaction

1992 • 43 citations

Genotype dependence of hepatitis C virus antibodies detectable by the first-generation enzyme-linked immunosorbent assay with C100-3 protein.

1993 • 43 citations

Clinical course of acute hepatitis C and changes in HCV markers

1994 • 42 citations

Heterosexual transmission of hepatitis C virus in family groups without risk factors.

1992 • 41 citations

Non-A, non-B chronic hepatitis is chronic hepatitis C: A sensitive assay for detection of hepatitis C virus RNA in the liver

1992 • 41 citations

Virus safety of human immunoglobulins: Efficient inactivation of hepatitis C and other human pathogenic viruses by the manufacturing procedure

1992 • 40 citations

Prevalence of hepatitis C virus in family members of patients with Hepatitis C

1993 • 40 citations

HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH)

1991 • 40 citations

Detection of antigens related to hepatitis C virus RNA encoding the NS5 region in the livers of patients with chronic type C hepatitis

1994 • 39 citations

Serum hepatitis C virus (HCV)‐RNA and response to alpha‐interferon in anti‐HCV positive chronic hepatitis

1992 • 39 citations

Sequential change of the hypervariable region of the hepatitis C virus genome in acute infection

1994 • 39 citations

Treatment of chronic sporadic-type non-A, non-B hepatitis with lymphoblastoid interferon: Gamma GT levels predictive for response

1994 • 38 citations

Hepatitis C infection unrelated to blood transfusion in hemodialysis patients

1994 • 38 citations

Direct detection of circulating hepatitis C virus RNA using probes from the 5' untranslated region.

1992 • 38 citations

Posttransfusion hepatitis revisited by hepatitis C antibody assays and polymerase chain reaction

1992 • 37 citations

Prospective study of the evaluation of hepatitis C virus infectivity in a high‐purity, solvent/detergent‐treated factor VIII concentrate: parallel evaluation of other markers for lipid‐enveloped and non‐lipid‐ enveloped viruses.

1993 • 37 citations

HEPATITIS C VIRUS INFECTION AND ALLOGENEIC BONE MARROW TRANSPLANTATION

1994 • 37 citations

Non-radioactive hybridization with hepatitis C virus-specific probes created during polymerase chain reaction: a fast and simple procedure to verify hepatitis C virus infection

1992 • 36 citations

Detection of hepatitis C viral RNA sequences in fresh and paraffin-embedded liver biopsy specimens of non-A, non-B hepatitis patients

1992 • 36 citations

Characterization and Mapping of a B-Cell Immunogenic Domain in Hepatitis C Virus E2 Glycoprotein Using a Yeast Peptide Library

1994 • 35 citations

Hepatitis C virus: From epidemiology and molecular virology to immunobiology Koziel MJ, Dudley D, Afdhal N, Choo Q-L, Houghton M, Ralston R, Walker B. Hepatitis C virus (HCV): specific cytotoxic t lymphocytes recognized epitopes in the core and envelope proteins of HCV. J Virol 1993;67: 7522–7532

1994 • 34 citations

Silent Mother-to-Child Transmission of Hepatitis C Virus through Two Generations Determined by Comparative Nucleotide Sequence Analysis of the Viral cDNA

1992 • 34 citations

Identification of hepatitis C viruses with a nonconserved sequence of the 5' untranslated region

1992 • 34 citations

Long‐term carriage of hepatitis C virus with normal aminotransferase after interferon treatment in patients with chronic hepatitis C

1993 • 34 citations

Post-transfusional anti-HCV-negative non-A non-B hepatitis (II) serological and polymerase chain reaction analysis for hepatitis C and hepatitis B viruses

1993 • 33 citations

High Prevalence of Antibodies to Hepatitis C Virus among Family Members of Patients with Anti-HCV-Positive Chronic Liver Disease

1993 • 33 citations

Serum ALT: Tarnished gold standard for interferon response in hepatitis C virus infection Johnson Y, Lau N, Mizokami M, Ohno T, Diamond DA, Kniffen J, Davis GL. Discrepancy between biochemical and virological responses to interferon-α in chronic hepatitis C. Lancet 1993; 342: 1208–1209

1994 • 33 citations

Clinical assessment and incidence of hepatitis C RNA in 50 consecutive RIBA‐positive volunteer blood donors

1992 • 32 citations

Prediction of hepatitis C virus infectivity in seropositive Australian blood donors by supplemental immunoassays and detection of viral RNA

1991 • 32 citations

Heterogeneity within the nonstructural protein 5-encoding region of hepatitis C viruses from a single patient

1992 • 31 citations

Nontransmission of hepatitis C from cadaver kidney donors to transplant recipients.

1993 • 31 citations

Hepatitis C Virus in Peripheral Blood Mononuclear Cells

1992 • 31 citations

Confirmation of Hepatitis C Virus Positive Blood Donors by Immunoblotting and Polymerase Chain Reaction

1992 • 30 citations

Lack of evidence for a role of HCV in hepatitis-associated aplastic anaemia

1993 • 29 citations

IgM antibody to a hepatitis C virus core peptide (CP14) for monitoring activity of liver disease in patients with acute or chronic hepatitis C

1994 • 29 citations

Seroprevalence of hepatitis B and C in a Merseyside hospital for the mentally handicapped

1994 • 28 citations

Immunohistochemical detection of the NS4 antigen of hepatitis C virus and its relation to histopathology.

1993 • 28 citations

Hepatitis C virus RNA in serum of blood donors with or without elevated transaminase levels

1993 • 27 citations

Chronic non-B, non-C hepatitis among blood donors assessed with HCV third generation tests and polymerase chain reaction

1993 • 27 citations

Use of confirmatory assays for diagnosis of hepatitis C viral infection in patients with hepatocellular carcinoma

1994 • 27 citations

Quantitative analysis of antibodies to hepatitis C virus during interferon-α therapy

1993 • 27 citations

Autoimmune Chronic Active Hepatitis: Changing Reactivity for Antibodies to Hepatitis C Virus after Immunosuppressive Treatment

1990 • 27 citations

Genetic variation of the hepatitis C virus (HCV) genome: random events or a clinically relevant issue?

1993 • 26 citations

Viruses and auto‐immune hepatitis

1994 • 25 citations

Second generation hepatitis C virus assays: Performance when testing african sera

1993 • 25 citations

Recombinant immunoblot and polymerase chain reaction testing in volunteer whole blood donors screened by a multi‐antigen assay for hepatitis C virus antibodies

1993 • 24 citations

Genetic alteration of the hepatitis C virus hypervariable region obtained from an asymptomatic carrier

1994 • 24 citations

Interaction of hepatitis B and hepatitis C infection in haemophilia

1993 • 24 citations

Association between hepatitis C virus and hepatocellular carcinoma using assays based on structural and nonstructural hepatitis C virus peptides.

1992 • 24 citations

Successful allogeneic bone marrow transplantation in an adult with aplastic anemia following orthotopic liver transplantation for non-A, non-B, non-C hepatitis.

1993 • 23 citations

Variability of IgM response in hepatitis C virus infection

1993 • 23 citations

A sensitive PCR method for detecting HCV RNA in plasma pools, blood products, and single donations

1994 • 23 citations

Seroprevalence of hepatitis C antibody in Peru

1992 • 23 citations

Antibodies and viremia in acute post‐transfusion hepatitis C: A prospective study

1994 • 22 citations

Chronic Non-A, Non-B Hepatitis in Pregnancy: Outcome and Possible Transmission to the Offspring

1989 • 22 citations

B-cell epitopes on the hepatitis C virus nucleocapsid protein determined by human monospecific antibodies

1993 • 22 citations

Histologically advanced chronic hepatitis C treated with recombinant alpha-interferon: a randomized placebo-controlled double-blind cross-over study

1993 • 21 citations

Second‐Generation Hepatitis C Elisa Antibody Tests Confirmed by the Four‐Antigen Recombinant Immunoblot Assay Correlate Well with Hepatitis C Viremia and Chronic Liver Disease in Swedish Blood Donors

1993 • 21 citations

Long-term response to higher doses of interferon (IFN) alfa-2b treatment of patients with chronic hepatitis C: A randomized multicenter trial

1993 • 21 citations

Prevalence of antibodies to hepatitis C virus in patients on peritoneal dialysis--a multicenter study.

1993 • 20 citations

HCV RNA and antibody to HCV core protein in Japanese patients with chronic liver disease

1992 • 20 citations

Seroconversion to hepatitis C Virus Antibodies in Patients with Acute Posttransfusion non-A, non-B Hepatitis in Sweden with a Second Generation Test

1992 • 20 citations

Surrogate markers are not useful for identification of HCV carriers in chronic hemodialysis patients

1991 • 20 citations

Transmission of hepatitis C via anaesthetic tubing?

1994 • 19 citations

Association of hepatitis C virus carrier state with the occurrence of hepatitis C virus core antibodies

1992 • 19 citations

Prospective assessment of donor blood screening for antibody to hepatitis C virus and high-titer antibody to HBcAg as a means of preventing posttransfusion hepatitis

1993 • 19 citations

Treatment of posttransfusion non-A, non-B acute and chronic hepatitis with human fibroblast beta-interferon: a preliminary report.

1989 • 19 citations

The effect on the safety of intravenous immunoglobulin of testing plasma for antibody to hepatitis C

1994 • 19 citations

Hepatitis C Viraemia in United Kingdom Blood Donors

1992 • 19 citations

Improved diagnosis of chronic hepatitis C virus infection by detection of antibody to multiple epitopes: Confirmation by antibody to synthetic oligopeptides

1992 • 18 citations

Long‐term follow‐up of anti‐hepatitis C virus antibodies in patients with acute nonA nonB hepatitis and different outcome of liver disease

1992 • 18 citations

Severe aplastic anemia associated with seronegative community-acquired hepatitis C virus infection

1993 • 17 citations

Immunoglobulin Preparation: Safe from Virus Transmission?

1989 • 17 citations

Molecular basis for antibody cross-reactivity between the hepatitis C virus core protein and the host-derived GOR protein

1994 • 15 citations

aplastic anemia and hepatitis C: Molecular biology exonerates another suspect Hibbs J, Frickhofen N, Rosenfeld S, Feinstone S, Kojima S, Bacigalupo A, Locasciulli A, et al. Aplastic anemia and viral hepatitis: non-A, non-B, non-C? JAMA 1992;267:2051–2054

1993 • 15 citations

Detection of hepatitis C virus antibodies with new recombinant antigens: assessment in chronic liver diseases

1992 • 14 citations

Early Appearance of Antibodies to Hepatitis C Virus in Community Acquired Acute Non-A, Non-B Hepatitis is Associated with Progression to Chronic Liver Disease

1990 • 14 citations

Diagnostic and clinical implications of the different genotypes of hepatitis C virus Nagayama R, Tsuda F, Okamoto H, Wang Y, Mitsui T, Tanaka T, Miyakawa Y, Mayumi M. Genotype dependence of hepatitis C virus antibodies detectable by the first-generation enzyme-linked immunosorbent assay with C100-3 protein. J Clin Invest 1993;92:1529?1533

1994 • 13 citations

Improved Detection of Antibodies to Hepatitis C Virus Using a Second Generation Elisa

1992 • 13 citations

Clinical significance of hepatitis C virus (HCV) infection in liver transplant recipients

1994 • 11 citations

Prevalence of hepatitis C virus antibody in a liver transplantation population

1992 • 11 citations

Etiological investigation of acute post‐transfusion non‐A, non‐B hepatitis in China

1993 • 11 citations

Hepatitis C virus antibody detection by a line ImmunoAssay and (near) full length genomic RNA detection by a new RNA‐capture polymerase chain reaction

1992 • 11 citations

Anti-Hepatitis C Virus Screening Will Reduce the Incidence of Post-Transfusion Hepatitis C Also in Low-Risk Areas

1992 • 10 citations

Hepatitis C virus testing in primary biliary cirrhosis

1992 • 10 citations

Chronic hepatitis B and C

1992 • 10 citations

Hepatitis C virus seroprevalence in the developmentally disabled.

1992 • 9 citations

Risk of Liver Disease in HCV-Seropositive Kidney Transplant Recipients

1993 • 9 citations

HCV RNA in patients with chronic hepatitis C treated with interferon‐α

1993 • 8 citations

Blood exchanged in ritual ceremonies as a possible route for infection with hepatitis C virus.

1994 • 8 citations

Absence of nonpercutaneous transmission of hepatitis C virus in a colony of Chimpanzees

1993 • 8 citations

Immunoglobulin preparations from hepatitis C antibody-positive plasma donors: influence on diagnosis and risk of infection in heart transplant recipients

1992 • 7 citations

Gamma Globulin Prophylaxis to Reduce Post-Transfusion Non-A, Non-B Hepatitis After Cardiac Surgery with Cardiopulmonary Bypass

1991 • 6 citations

Enzyme Immunoassays for Anti-Hepatitis C Virus Antibodies Improved Specificity and Analytical Sensitivity by Combination of Three Different Recombinant Viral Proteins in Second Generation Tests

1992 • 5 citations

Gene transefer as a new mode of vaccination: Implications for HCV

1993 • 4 citations

Viral hepatitis

1992 • 4 citations