Significance of serum hepatitis C virus RNA levels in chronic hepatitis C

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

Avoiding false positives with PCR

1989 • 3,564 citations

Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis

1981 • 3,549 citations

An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis

1989 • 3,401 citations

Detection of Antibody to Hepatitis C Virus in Prospectively Followed Transfusion Recipients with Acute and Chronic Non-A, Non-B Hepatitis

1989 • 1,698 citations

Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa

1989 • 1,658 citations

Recombinant Interferon Alfa Therapy for Chronic Hepatitis C

1989 • 1,233 citations

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

1990 • 1,208 citations

HEPATITIS C VIRUS ANTIBODIES AMONG RISK GROUPS IN SPAIN

1989 • 910 citations

Detection of hepatitis C viral sequences in non-A, non-B hepatitis

1990 • 732 citations

Detection of hepatitis C virus by polymerase chain reaction and response to interferon-α therapy: Relationship to genotypes of hepatitis C virus

1992 • 689 citations

Decrease in Serum Hepatitis C Viral RNA during Alpha-Interferon Therapy for Chronic Hepatitis C

1991 • 383 citations

The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients

1992 • 295 citations

At least five related, but distinct, hepatitis C viral genotypes exist.

1992 • 267 citations

Non-A, non-B hepatitis specific antibodies directed at host-derived epitope: implication for an autoimmune process

1990 • 226 citations

Luminescence Immunoassay and Molecular Applications

1990 • 165 citations

Hepatitis C virus antigen in hepatocytes: Immunomorphologic detection and identification

1992 • 153 citations

Impact of specimen handling and storage on detection of hepatitis C virus RNA

1992 • 152 citations

Polymerase chain reaction assay for hepatitis C virus RNA using a single tube for reverse transcription and serial rounds of amplification with nested primer pairs

1992 • 51 citations

Significance of antibody to the host cellular gene derived epitope GOR in chronic hepatitis C virus infection

1993 • 50 citations

An oligonucleotide probe for the detection of hepatitis B virus DNA in serum

1987 • 29 citations

Correlation between the serum level of hepatitis C virus RNA and disease activities in acute and chronic hepatitis C

1992 • 25 citations