Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis

1989 • 3,401 citations

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

1991 • 1,849 citations

Genetic organization and diversity of the hepatitis C virus.

1991 • 1,717 citations

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

1990 • 1,208 citations

Hepatitis C virus infection is associated with the development of hepatocellular carcinoma.

1990 • 1,108 citations

Structure and organization of the hepatitis C virus genome isolated from human carriers

1991 • 970 citations

Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease

1991 • 854 citations

Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

1992 • 712 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups.

1990 • 640 citations

Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis.

1991 • 636 citations

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.

1988 • 626 citations

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins

1991 • 611 citations

Nucleotide sequence and mutation rate of the H strain of hepatitis C virus.

1991 • 609 citations

Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: Comparative study of four distinct genotypes

1992 • 578 citations

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

1988 • 540 citations

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

1988 • 514 citations

Nucleotide sequence of the genomic RNA of hepatitis C virus isolated from a human carrier: comparison with reported isolates for conserved and divergent regions

1991 • 476 citations

Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus

1993 • 476 citations

Analysis of a new hepatitis C virus type and its phylogenetic relationship to existing variants

1992 • 430 citations

Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

1988 • 412 citations

Sequence analysis of the 5' noncoding region of hepatitis C virus.

1992 • 410 citations

Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: Variability and stability

1992 • 384 citations

Hypervariable regions in the putative glycoprotein of hepatitis C virus

1991 • 353 citations

There are two major types of hepatitis C virus in Japan

1990 • 335 citations

Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting

1991 • 288 citations

Genomic structure of the human prototype strain H of hepatitis C virus: comparison with American and Japanese isolates.

1991 • 281 citations

At least five related, but distinct, hepatitis C viral genotypes exist.

1992 • 267 citations

Pestivirus glycoprotein which induces neutralizing antibodies forms part of a disulfide-linked heterodimer

1990 • 247 citations

The Taiwanese hepatitis C virus genome: Sequence determination and mapping the 5′ termini of viral genomic and antigenomic RNA

1992 • 189 citations

Marked sequence diversity in the putative envelope proteins of hepatitis C viruses

1992 • 177 citations

A new type of hepatitis C virus in patients in Thailand

1992 • 171 citations

Sequence analysis of the 5' nincoding region of hepatitis C virus

1992 • 165 citations

A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan

1989 • 164 citations

The Putative Nucleocapsid and Envelope Protein Genes of Hepatitis C Virus Determined by Comparison of the Nucleotide Sequences of Two Isolates Derived from an Experimentally Infected Chimpanzee and Healthy Human Carriers

1990 • 151 citations

Molecular cloning of hepatitis C virus genome from a single Japanese carrier: sequence variation within the same individual and among infected individuals

1992 • 148 citations

Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus

1992 • 142 citations

Type-Restricted Neutralization of Molecular Clones of Human Immunodeficiency Virus

1988 • 115 citations

A second group of hepatitis C viruses

1991 • 95 citations

Prevalence of Antibody against Non-A, non-B Hepatitis Virus in Japanese Patients with Hepatocellular Carcinoma

1990 • 90 citations

Japanese isolates of the non-A, non-B hepatitis viral genome show sequence variations from the original isolate in the U.S.A.

1989 • 56 citations

Distribution of plural HCV types in Japan

1991 • 52 citations

A structural protein of hepatitis C virus expressed in E. coli facilitates accurate detection of hepatitis C virus

1990 • 52 citations

Sequence diversity of hepatitis C viral genomes.

1990 • 50 citations

Molecular structure of the Japanese hepatitis C viral genome

1991 • 45 citations

Correlation between the serum level of hepatitis C virus RNA and disease activities in acute and chronic hepatitis C

1992 • 25 citations

A Structural Protein Encoded by the 5′ Region of the Hepatitis C Virus Genome Efficiently Detects Viral Infection

1990 • 5 citations