Detection and quantification of hepatitis C virus RNA replication in the liver

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

Avoiding false positives with PCR

1989 • 3,564 citations

An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis

1989 • 3,401 citations

FLAVIVIRUS GENOME ORGANIZATION, EXPRESSION, AND REPLICATION

1990 • 1,903 citations

Genetic organization and diversity of the hepatitis C virus.

1991 • 1,717 citations

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

1990 • 1,208 citations

Detection of hepatitis C viral sequences in non-A, non-B hepatitis

1990 • 732 citations

Detection of hepatitis C virus RNA by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5'-noncoding region.

1990 • 548 citations

Evaluation of Antibodies to Hepatitis C Virus in a Study of Transfusion-Associated Hepatitis

1990 • 388 citations

Detection of replicative intermediates of hepatitis C viral RNA in liver and serum of patients with chronic hepatitis C.

1991 • 207 citations

Detection of the minus strand of hepatitis C virus RNA by reverse transcription and polymerase chain reaction: Implications for hepatitis C virus replication in infected tissue

1992 • 127 citations

Immunohistochemical Detection of Hepatitis C Virus-Infected Hepatocytes in Chronic Liver Disease With Monoclonal Antibodies to Core, Envelope and Ns3 Regions of the Hepatitis C Virus Genome

1992 • 125 citations

Detection of Hepatitis C Virus RNA in Sera and Liver Tissues of Non‐A, Non‐B Hepatitis Patients Using the Polymerase Chain Reaction

1990 • 53 citations

Antibodies to hepatitis C virus in community-acquired acute non-A, non-B hepatitis

1991 • 42 citations

Correlation of plasma hepatitis C virus RNA levels with serum alanine aminotransferase in non‐A, non‐B chronic liver disease

1993 • 31 citations

Detection and partial sequencing of hepatitis C virus RNA in the liver

1991 • 20 citations

Detection of hepatitis C viral RNA in sporadic acute non-A, non-B hepatitis by polymerase chain reaction

1993 • 15 citations