Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Cell locomotion and focal adhesions are regulated by substrate flexibility

1997 • 2,930 citations

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1993 • 2,169 citations

A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation.

1986 • 1,644 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages

1997 • 1,218 citations

The Fibronectin Domain ED-A Is Crucial for Myofibroblastic Phenotype Induction by Transforming Growth Factor-β1

1998 • 801 citations

2.0 Å Crystal Structure of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop and Synergy Region

1996 • 621 citations

Rho-mediated Contractility Exposes a Cryptic Site in Fibronectin and Induces Fibronectin Matrix Assembly

1998 • 589 citations

Molecular interactions in cell adhesion complexes

1997 • 583 citations

Mechanisms of Myofibroblast Activity and Phenotypic Modulation

1999 • 580 citations

Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

2000 • 574 citations

Focal adhesions – the cytoskeletal connection

2000 • 569 citations

The fibronexus: a transmembrane association of fibronectin-containing fibers and bundles of 5 nm microfilaments in hamster and human fibroblasts

1979 • 536 citations

Interdependent SMAD and JNK Signaling in Transforming Growth Factor-β-mediated Transcription

1999 • 534 citations

Fibronectins

1990 • 523 citations

The Molecular Architecture of Focal Adhesions

1995 • 479 citations

Transforming Growth Factor-β1 Promotes the Morphological and Functional Differentiation of the Myofibroblast

2000 • 466 citations

Integrin Dynamics and Matrix Assembly

2000 • 459 citations

Molecular diversity of cell-matrix adhesions

1999 • 444 citations

Physical State of the Extracellular Matrix Regulates the Structure and Molecular Composition of Cell-Matrix Adhesions

2000 • 402 citations

Partial primary structure of bovine plasma fibronectin: Three types of internal homology

1983 • 399 citations

Involvement of microtubules in the control of adhesion-dependent signal transduction

1996 • 358 citations

Alignment of fibroblasts on grooved surfaces described by a simple geometric transformation

1986 • 333 citations

Formation of cell-to-substrate contacts during fibroblast motility: An interference-reflexion study

1980 • 307 citations

In vivo co-distribution of fibronectin and actin fibers in granulation tissue: immunofluorescence and electron microscope studies of the fibronexus at the myofibroblast surface.

1984 • 261 citations

Fibronectin Matrix Regulates Activation of RHO and CDC42 GTPases and Cell Cycle Progression

1998 • 234 citations

Monoclonal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed human cells.

1987 • 204 citations

Structure and function of fibronectin modules

1996 • 204 citations

Modulation of Cell-adhesive Activity of Fibronectin by the Alternatively Spliced EDA Segment

1997 • 189 citations

The Compact Conformation of Fibronectin Is Determined by Intramolecular Ionic Interactions

1999 • 176 citations

Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation

1994 • 147 citations

Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis.

1990 • 141 citations

Fibronectin Regulates Assembly of Actin Filaments and Focal Contacts in Cultured Cells via the Heparin-binding Site in Repeat III₁₃

1999 • 130 citations

Molecular Interactions in the Submembrane Plaque of Cell-Cell and Cell-Matrix Adhesions

1995 • 125 citations

The Fibronectin Extra Domain A Activates Matrix Metalloproteinase Gene Expression by an Interleukin-1-dependent Mechanism

1999 • 114 citations

Polarized distribution of actin isoforms in gastric parietal cells.

1995 • 111 citations

Brief Review of the Fibronexus and Its Significance for Myofibroblastic Differentiation and Tumor Diagnosis

1993 • 104 citations

The fibronectin cell attachment sequence Arg-Gly-Asp-Ser promotes focal contact formation during early fibroblast attachment and spreading.

1987 • 96 citations

Localization of the cellular‐fibronectin‐specific epitope recognized by the monoclonal antibody IST‐9 using fusion proteins expressed in E. coli

1987 • 92 citations

Focal contacts of normal and RSV-transformed quail cells

1985 • 90 citations

A precursor of the focal contact in cultured fibroblasts

1988 • 90 citations

The Early Development of the Marsupialia, with Special Reference to the Native Cat (Dasyurus Viverrinus).

1910 • 82 citations

Rat Fibroblasts Cultured from Various Organs Exhibit Differences in α-Smooth Muscle Actin Expression, Cytoskeletal Pattern, and Adhesive Structure Organization

1998 • 75 citations

TGF-β1 Stimulation of Fibronectin Transcription in Cultured Human Lung Fibroblasts Requires Active Geranylgeranyl Transferase I, Phosphatidylcholine-Specific Phospholipase C, Protein Kinase C-δ, and p38, But Not erk1/erk2

2000 • 59 citations

Adhesion Activity in Fibronectin's Alternatively Spliced Domain EDa (EIIIA): Complementarity to Plasma Fibronectin Functions

1995 • 41 citations

Maturation of Cell-Substratum Focal Adhesions Induced by Depolymerization of Microtubules is Mediated by Increased Cortical Tension

1998 • 41 citations

Plasminogen Activator Expression in Rat Arterial Smooth Muscle Cells Depends on Their Phenotype and Is Modulated by Cytokines

1998 • 41 citations

Adhesion Activity in Fibronectin's Alternatively Spliced Domain EDa (EIIIA) and Its Neighboring Type III Repeats: Oncogene-Dependent Regulation

1994 • 37 citations

Fibronexus formation is an early event during fibronectin-induced restoration of more normal morphology and substrate adhesion patterns in transformed hamster fibroblasts

1982 • 28 citations

Identification of Two Amino Acids within the EIIIA (ED-A) Segment of Fibronectin Constituting the Epitope for Two Function-blocking Monoclonal Antibodies

1999 • 25 citations

What the papers say. Rho, rac and the actin cytoskeleton

1992 • 23 citations

A quantitative analysis of alterations in the shape of cultured fibroblasts induced by tumour-promoting phorbol ester

1989 • 21 citations

Actin-associated proteins related to focal and close cell-substrate contacts in murine fibroblasts

1987 • 4 citations