The human cytomegalovirus UL37 immediate-early regulatory protein is an integral membrane N-glycoprotein which traffics through the endoplasmic reticulum and Golgi apparatus

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

1990 • 1,280 citations

Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf-liver microsomes

1975 • 863 citations

Characterization of membrane proteins in detergent solutions

1976 • 853 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

The DNA Sequence of Human Herpesvirus-6: Structure, Coding Content, and Genome Evolution

1995 • 556 citations

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

1995 • 544 citations

SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane.

1991 • 544 citations

Sequence specificity in the dimerization of transmembrane .alpha.-helixes

1992 • 490 citations

Retrieval of transmembrane proteins to the endoplasmic reticulum.

1993 • 414 citations

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein.

1990 • 360 citations

Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.

1986 • 334 citations

Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter

1987 • 223 citations

Formation and isomerization of disulfide bonds in proteins: Protein disulfide-isomerase

1984 • 216 citations

Monoclonal antibodies to human cytomegalovirus: three surface membrane proteins with unique immunological and electrophoretic properties specify cross-reactive determinants

1982 • 165 citations

Identification and characterization of three distinct families of glycoprotein complexes in the envelopes of human cytomegalovirus

1988 • 152 citations

Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis

1993 • 142 citations

Quaternary structure of influenza virus hemagglutinin after acid treatment

1986 • 138 citations

Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression

1992 • 134 citations

An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein

1988 • 123 citations

Processing of the gp55-116 envelope glycoprotein complex (gB) of human cytomegalovirus

1989 • 119 citations

The 86-kilodalton IE-2 protein of human cytomegalovirus is a sequence-specific DNA-binding protein that interacts directly with the negative autoregulatory response element located near the cap site of the IE-1/2 enhancer-promoter

1993 • 110 citations

An enhancer element in the short unique region of human cytomegalovirus regulates the production of a group of abundant immediate early transcripts

1988 • 110 citations

Synthesis and processing of the envelope gp55-116 complex of human cytomegalovirus

1986 • 109 citations

An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter.

1993 • 109 citations

Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes

1996 • 101 citations

Viral polypeptides detected by a complement-dependent neutralizing murine monoclonal antibody to human cytomegalovirus

1985 • 99 citations

Expression of the acidic nuclear immediate-early protein (IE1) of human cytomegalovirus in stable cell lines and its preferential association with metaphase chromosomes

1989 • 99 citations

Identification of binding sites for the 86-kilodalton IE2 protein of human cytomegalovirus within an IE2-responsive viral early promoter

1994 • 93 citations

Human cytomegalovirus UL36-38 and US3 immediate-early genes: temporally regulated expression of nuclear, cytoplasmic, and polysome-associated transcripts during infection

1991 • 89 citations

Expression of the human cytomegalovirus UL36–38 immediate early region during permissive infection

1991 • 88 citations

Human cytomegalovirus immediate-early gene 2 protein interacts with itself and with several novel cellular proteins

1993 • 84 citations

Identification and mapping of dimerization and DNA-binding domains in the C terminus of the IE2 regulatory protein of human cytomegalovirus

1993 • 82 citations

Identification of a transactivating function mapping to the putative immediate-early locus of human herpesvirus 6

1991 • 71 citations

Oligomerization of the human cytomegalovirus major envelope glycoprotein complex gB (gp55-116)

1992 • 68 citations

Expression of human cytomegalovirus UL36 and UL37 genes is required for viral DNA replication

1995 • 65 citations

Characterization of human immunodeficiency virus type 2 envelope glycoproteins: dimerization of the glycoprotein precursor during processing

1989 • 64 citations

Functional Roles of Immediate Early Proteins Encoded by the Human Cytomegalovirus UL36-38, UL115-119, TRS1/IRS1 and US3 Loci

1996 • 63 citations

Nucleotide sequence analysis of a 38.5-kilobase-pair region of the genome of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene homologs and transactivating functions

1994 • 55 citations

Immediate-early proteins of human cytomegalovirus strains AD169, Davis, and towne differ in electrophoretic mobility

1981 • 52 citations

Selective induction of chromosomal gene expression by human cytomegalovirus

1988 • 50 citations

Potent antiviral activity of an antisense oligonucleotide complementary to the intron-exon boundary of human cytomegalovirus genes UL36 and UL37

1995 • 48 citations

The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression

1993 • 39 citations

Nuclear compartmentation of glycoprotein B of human cytomegalovirus

1990 • 35 citations

Alternate promoter selection within a human cytomegalovirus immediate-early and early transcription unit (UL119-115) defines true late transcripts containing open reading frames for putative viral glycoproteins

1991 • 29 citations

RNA Analysis and Isolation of cDNAs Derived from the Human Cytomegalovirus Immediate-Early Region at 0.24 Map Units

1990 • 22 citations

Subcellular localization of the major immediate early protein (IE1) of human cytomegalovirus at early times after infection

1988 • 17 citations

Isolation and characterization of a human cytomegalovirus glycoprotein containing a high content of O-linked oligosaccharides

1988 • 16 citations

The Acidic Domain of the Human Cytomegalovirus UL37 Immediate Early Glycoprotein Is Dispensable for Its Transactivating Activity and Localization but Is Not for Its Synergism

1996 • 15 citations