Alternate promoter selection within a human cytomegalovirus immediate-early and early transcription unit (UL119-115) defines true late transcripts containing open reading frames for putative viral glycoproteins

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2001 • 133,517 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

1990 • 1,280 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Herpes simplex virus type 1 ICP27 is an essential regulatory protein

1985 • 462 citations

Cytomegalovirus: Biology and Infection.

1983 • 443 citations

Cytomegalovirus infects human lymphocytes and monocytes: virus expression is restricted to immediate-early gene products.

1984 • 407 citations

Detection of Human Cytomegalovirus in Peripheral Blood Lymphocytes in a Natural Infection

1985 • 365 citations

Structural analysis of the major immediate early gene of human cytomegalovirus

1984 • 342 citations

Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient

1989 • 329 citations

Temporal Patterns of Human Cytomegalovirus Transcription: Mapping the Viral RNAs Synthesized at Immediate Early, Early, and Late Times After Infection

1982 • 311 citations

Organization and expression of the immediate early genes of human cytomegalovirus

1983 • 288 citations

Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1

1985 • 270 citations

Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27

1990 • 247 citations

Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter

1987 • 223 citations

Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region

1989 • 216 citations

Transcription in human fibroblasts permissively infected by human cytomegalovirus strain AD169

1983 • 199 citations

Synthesis of Proteins and Glycoproteins in Cells Infected with Human Cytomegalovirus

1977 • 184 citations

Cytomegalovirus Infection of Human Blood Cells

1984 • 183 citations

Human cytomegalovirus DNA: Restriction enzyme cleavage maps and map locations for immediate-early, early, and late RNAs

1981 • 171 citations

Role of DNA replication in vaccinia virus gene expression: A naked template is required for transcription of three late trans-activator genes

1990 • 158 citations

The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection

1990 • 124 citations

An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein

1988 • 123 citations

A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection

1989 • 112 citations

An enhancer element in the short unique region of human cytomegalovirus regulates the production of a group of abundant immediate early transcripts

1988 • 110 citations

Autoregulation of the human cytomegalovirus major immediate-early gene

1985 • 107 citations

Cloning of the human cytomegalovirus genome as endonuclease XbaI fragments

1981 • 99 citations

Regulation and Tissue-Specific Expression of Human Cytomegalovirus

1990 • 95 citations

Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities

1989 • 92 citations

The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule

1989 • 83 citations

Regulation of cytomegalovirus late-gene expression: differential use of three start sites in the transcriptional activation of ICP36 gene expression

1989 • 73 citations

Post-transcriptional control of human cytomegalovirus gene expression

1983 • 69 citations

Promoter occlusion prevents transcription of adenovirus polypeptide IX mRNA until after DNA replication.

1989 • 67 citations

Identification and expression of a human cytomegalovirus early glycoprotein

1989 • 62 citations

Human Cytomegalovirus: Recent Aspects from Molecular Biology

1989 • 49 citations

Human Cytomegalovirus Early Gene Expression

1990 • 45 citations

Immediate-Early Transcription Regulation of Human Cytomegalovirus

1990 • 40 citations

Characterization of a human cytomegalovirus 1.6-kilobase late mRNA and identification of its putative protein product

1991 • 20 citations

Transcriptional analysis of the eight-kilobase mRNA encoding the major capsid protein of human cytomegalovirus

1990 • 15 citations

Human cytomegalovirus nucleic acids in tissues from congenitally infected infants

1989 • 13 citations

Transcription of the human cytomegalovirus glycoprotein gene family in the short unique component of the viral genome

1990 • 13 citations