Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

DNA sequence and expression of the B95-8 Epstein—Barr virus genome

1984 • 2,039 citations

Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

1990 • 1,280 citations

ANIMAL VIRUS DNA REPLICATION

1989 • 520 citations

Targeting the E1 Replication Protein to the Papillomavirus Origin of Replication by Complex Formation with the E2 Transactivator

1990 • 396 citations

Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus

1988 • 386 citations

Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis

1988 • 328 citations

Human cytomegalovirus encodes three G protein-coupled receptor homologues

1990 • 281 citations

A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen

1988 • 261 citations

trans-acting requirements for replication of Epstein-Barr virus ori-Lyt

1992 • 234 citations

A method for identifying the viral genes required for herpesvirus DNA replication.

1986 • 228 citations

Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins

1990 • 216 citations

The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions

1990 • 205 citations

The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity

1990 • 202 citations

Cloning of the complete human cytomegalovirus genome in cosmids

1982 • 198 citations

Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains

1990 • 197 citations

Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein

1983 • 179 citations

Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start site

1991 • 161 citations

Human cytomegalovirus. IV. Specific inhibition of virus-induced DNA polymerase activity and viral DNA replication by phosphonoacetic acid

1975 • 154 citations

Human cytomegalovirus. III. Virus-induced DNA polymerase

1975 • 154 citations

Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein.

1990 • 151 citations

Identification of the herpes simplex virus DNA polymerase gene

1977 • 149 citations

The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signal

1991 • 146 citations

Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression

1992 • 134 citations

Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells

1992 • 123 citations

Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene

1988 • 121 citations

An ICP6::lacZ insertional mutagen is used to demonstrate that the UL52 gene of herpes simplex virus type 1 is required for virus growth and DNA synthesis

1988 • 121 citations

Transactivation of the cytomegalovirus ICP36 gene promoter requires the alpha gene product TRS1 in addition to IE1 and IE2

1992 • 120 citations

The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently trans-activate the c-fos, c-myc and hsp70 promoters via basal promoter elements

1992 • 117 citations

E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection.

1992 • 115 citations

Sequence of the short unique region, short repeats, and part of the long repeats of human cytomegalovirus

1986 • 114 citations

Human cytomegalovirus immediate-early two protein region involved in negative regulation of the major immediate-early promoter

1990 • 100 citations

Specific transcription factors stimulate simian virus 40 and polyomavirus origins of DNA replication.

1992 • 99 citations

Control of human papillomavirus type 11 origin of replication by the E2 family of transcription regulatory proteins

1992 • 99 citations

Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination

1990 • 93 citations

Responsiveness of the Epstein-Barr virus NotI repeat promoter to the Z transactivator is mediated in a cell-type-specific manner by two independent signal regions

1989 • 92 citations

Human cytomegalovirus origin of DNA replication (oriLyt) resides within a highly complex repetitive region.

1992 • 89 citations

Human cytomegalovirus UL36-38 and US3 immediate-early genes: temporally regulated expression of nuclear, cytoplasmic, and polysome-associated transcripts during infection

1991 • 89 citations

Expression of the human cytomegalovirus UL36–38 immediate early region during permissive infection

1991 • 88 citations

A cluster of dispensable genes within the human cytomegalovirus genome short component: IRS1, US1 through US5, and the US6 family

1992 • 87 citations

Boundaries and structure of human cytomegalovirus oriLyt, a complex origin for lytic-phase DNA replication

1992 • 87 citations

Association of Epstein-Barr virus early antigen diffuse component and virus-specified DNA polymerase activity

1987 • 76 citations

A discrete cis element in the human immunodeficiency virus long terminal repeat mediates synergistic trans activation by cytomegalovirus immediate-early proteins

1991 • 74 citations

E2F Mediates Dihydrofolate Reductase Promoter Activation and Multiprotein Complex Formation in Human Cytomegalovirus Infection

1992 • 68 citations

Cooperation of EBV DNA Polymerase and EA-D(BMRFl)in vitro and colocalization in nuclei of infected cells

1991 • 65 citations

Multicomponent origin of cytomegalovirus lytic-phase DNA replication

1991 • 65 citations

Precise localization of genes on large animal virus genomes: use of lambda gt11 and monoclonal antibodies to map the gene for a cytomegalovirus protein family.

1985 • 64 citations

A temperature-sensitive mutation in a herpes simplex virus type 1 gene required for viral DNA synthesis maps to coordinates 0.609 through 0.614 in UL

1988 • 60 citations

Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene

1987 • 59 citations

Isolation and characterization of herpes simplex virus type 1 host range mutants defective in viral DNA synthesis

1988 • 54 citations

Physical Mapping of Temperature-sensitive Mutations of Herpes Simplex Virus Type 1 Using Cloned Restriction Endonuclease Fragments

1983 • 47 citations

Specific Transcription Factors Stimulate Simian Virus 40 and Polyomavirus Origins of DNA Replication

1992 • 45 citations

An isoform variant of the cytomegalovirus immediate-early auto repressor functions as a transcriptional activator

1992 • 43 citations

Temperature-sensitive Mutants in Two Distinct Complementation Groups of Herpes Simplex Virus Type 1 Specify Thermolabile DNA Polymerase

1981 • 37 citations

Identification and characterization of a major early cytomegalovirus DNA-binding protein

1986 • 34 citations

Two specific topoisomerase II inhibitors prevent replication of human cytomegalovirus DNA: an implied role in replication of the viral genome

1988 • 31 citations

High level expression of DNA polymerases from herpesviruses

1991 • 29 citations

The 89,000-Mr murine cytomegalovirus immediate-early protein stimulates c-fos expression and cellular DNA synthesis

1988 • 22 citations

Immunological characterization of an early cytomegalovirus single-strand DNA-binding protein with similarities to the HSV major DNA-binding protein

1987 • 17 citations

Human cytomegalovirus major immediate early gene product can induce SV40 DNA replication in human embryonic lung cells

1990 • 9 citations

Deleted Work

1955 • 0 citations