Nucleotide sequence analysis of a 38.5-kilobase-pair region of the genome of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene homologs and transactivating functions

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

DNA sequence and expression of the B95-8 Epstein—Barr virus genome

1984 • 2,039 citations

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 • 1,618 citations

IDENTIFICATION OF HUMAN HERPESVIRUS-6 AS A CAUSAL AGENT FOR EXANTHEM SUBITUM

1988 • 1,448 citations

The Complete DNA Sequence of Varicella-Zoster Virus

1986 • 1,425 citations

Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

1990 • 1,280 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

The familyHerpesviridae: an update

1992 • 614 citations

Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1

1985 • 523 citations

Primary structure of the herpesvirus saimiri genome

1992 • 440 citations

Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases.

1988 • 405 citations

Graphic methods to determine the function of nucleic acid sequences

1984 • 367 citations

The current status and portability of our sequence handling software

1986 • 357 citations

In vitro cellular tropism of human B-lymphotropic virus (human herpesvirus-6).

1988 • 318 citations

Productive dual infection of human CD4+ T lymphocytes by HIV-1 and HHV-6

1989 • 308 citations

Predominant CD4 T-lymphocyte tropism of human herpesvirus 6-related virus

1989 • 307 citations

[7] Random cloning and sequencing by the M13/dideoxynucleotide chain termination method

1987 • 292 citations

Organization and expression of the immediate early genes of human cytomegalovirus

1983 • 288 citations

Human cytomegalovirus encodes three G protein-coupled receptor homologues

1990 • 281 citations

Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1

1985 • 270 citations

Induction of CD4 and susceptibility to HIV-1 infection in human CD8+ T lymphocytes by human herpesvirus 6

1991 • 259 citations

Measurements of the effects that coding for a protein has on a DNA sequence and their use for finding genes

1984 • 254 citations

Human herpesvirus 6 is closely related to human cytomegalovirus

1990 • 251 citations

Related functional domains in virus DNA polymerases.

1987 • 243 citations

trans-acting requirements for replication of Epstein-Barr virus ori-Lyt

1992 • 234 citations

Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri

1990 • 222 citations

The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle

1989 • 218 citations

Human herpes virus-6 increases HIV-1 expression in co-infected T cells via nuclear factors binding to the HIV-1 enhancer.

1989 • 205 citations

The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions

1990 • 205 citations

The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity

1990 • 202 citations

On the predictive recognition of signal peptide sequences

1985 • 201 citations

The Epstein-Barr virus Zta transactivator: a member of the bZIP family with unique DNA-binding specificity and a dimerization domain that lacks the characteristic heptad leucine zipper motif

1990 • 199 citations

Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins

1992 • 193 citations

Infection of natural killer cells by human herpesvirus 6

1993 • 192 citations

The DNA Sequences of the Long Repeat Region and Adjoining Parts of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 • 172 citations

Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene

1987 • 170 citations

The structure of the major immediate early gene of human cytomegalovirus strain AD169

1985 • 170 citations

Molecular Biology of Visual Pigments

1987 • 168 citations

Protein counterparts of human and simian cytomegaloviruses

1983 • 167 citations

Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis

1993 • 142 citations

Herpes Simplex and 'The Herpes Complex': Diverse Observations and A Unifying Hypothesis

1984 • 142 citations

Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression

1992 • 134 citations

Unity and Diversity in the Herpesviruses

1977 • 128 citations

Deviations from Expected Frequencies of CpG Dinucleotides in Herpesvirus DNAs May Be Diagnostic of Differences in the States of Their Latent Genomes

1989 • 123 citations

Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3

1992 • 123 citations

An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein

1988 • 123 citations

Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells

1992 • 123 citations

Transactivation of human immunodeficiency virus promoter by human herpesvirus 6

1989 • 122 citations

The 65,000-Mr DNA-binding and virion trans-inducing proteins of herpes simplex virus type 1

1987 • 121 citations

Transactivation of the cytomegalovirus ICP36 gene promoter requires the alpha gene product TRS1 in addition to IE1 and IE2

1992 • 120 citations

THE GENOMES OF THE HUMAN HERPESVIRUSES: Contents, Relationships, and Evolution

1989 • 116 citations

Sequence of the short unique region, short repeats, and part of the long repeats of human cytomegalovirus

1986 • 114 citations

The Genome of Human Herpesvirus 6: Maps of Unit-length and Concatemeric Genomes for Nine Restriction Endonucleases

1991 • 111 citations

An enhancer element in the short unique region of human cytomegalovirus regulates the production of a group of abundant immediate early transcripts

1988 • 110 citations

Map position and nucleotide sequence of the gene for the large structural phosphoprotein of human cytomegalovirus

1987 • 109 citations

Suppression of Human Immunodeficiency Virus Type 1 Replication by Human Herpesvirus-6

1990 • 104 citations

Linear amplification sequencing, a powerful method for sequencing DNA

1991 • 97 citations

The Ribonucleotide Reductase Induced by Herpes Simplex Virus Type 1 Involves Minimally a Complex of Two Polypeptides (136K and 38K)

1985 • 95 citations

DNA-binding protein associated with herpes simplex virus DNA polymerase

1985 • 89 citations

Expression of the human cytomegalovirus UL36–38 immediate early region during permissive infection

1991 • 88 citations

Genetic relationships between bovine herpesvirus 4 and the gammaherpesviruses epstein-Barr virus and herpesvirus saimiri

1992 • 87 citations

Structural features of ribonucleotide reductase

1986 • 74 citations

Regulation of cytomegalovirus late-gene expression: differential use of three start sites in the transcriptional activation of ICP36 gene expression

1989 • 73 citations

Identification of a transactivating function mapping to the putative immediate-early locus of human herpesvirus 6

1991 • 71 citations

Lack of Correlation between Human Herpesvirus-6 Infection and the Course of Human Immunodeficiency Virus Infection

1990 • 68 citations

Characterization of the DNA polymerase gene of human herpesvirus 6

1991 • 67 citations

Cooperation of EBV DNA Polymerase and EA-D(BMRFl)in vitro and colocalization in nuclei of infected cells

1991 • 65 citations

Identification of a nucleocapsid protein as a specific serological marker of human herpesvirus 6 infection

1990 • 64 citations

Identification of the human herpesvirus 6 glycoprotein H and putative large tegument protein genes

1991 • 61 citations

Identification, characterization, and sequence analysis of a cDNA encoding a phosphoprotein of human herpesvirus 6

1991 • 60 citations

The unique region of the human herpesvirus 6 genome is essentially collinear with the UL segment of human cytomegalovirus

1991 • 59 citations

Identification and separation of the two subunits of the herpes simplex virus ribonucleotide reductase

1986 • 54 citations

Regulation of the herpesvirus saimiri (HVS) delayed-early 110-kilodalton promoter by HVS immediate-early gene products and a homolog of the Epstein-Barr virus R trans activator

1991 • 53 citations

Transactivation of the human immunodeficiency virus promoter by human herpesvirus 6 (HHV-6) strains GS and Z-29 in primary human T lymphocytes and identification of transactivating HHV-6(GS) gene fragments

1991 • 50 citations

Herpes Simplex Virus Ribonucleotide Reductase Induced in Infected BHK-21/C13 Cells: Biochemical Evidence for the Existence of Two Non-identical Subunits, H1 and H2

1985 • 50 citations

Characterization of the bovine herpesvirus 4 major immediate-early transcript

1991 • 50 citations

Gene for the major antigenic structural protein (p100) of human herpesvirus 6

1992 • 48 citations

Identification and characterization of a human herpesvirus 6 gene segment that trans activates the human immunodeficiency virus type 1 promoter

1992 • 48 citations

Characterization of a bovine herpesvirus 4 immediate-early RNA encoding a homolog of the Epstein-Barr virus R transactivator

1993 • 47 citations

Gene expression in cells infected with gammaherpesvirus saimiri: properties of transcripts from two immediate-early genes

1990 • 46 citations

Identification of homologues to the human cytomegalovirus US22 gene family in human herpesvirus 6

1992 • 44 citations

Identification of the Genes Encoding Two Capsid Proteins of Herpes Simplex Virus Type 1 by Direct Amino Acid Sequencing

1990 • 43 citations

Physical mapping and nucleotide sequence of a herpes simplex virus type 1 gene required for capsid assembly

1989 • 42 citations

Analysis of nucleotide sequence of the rightmost 43 kbp of herpesvirus saimiri (HVS) L-DNA: General conservation of genetic organization between HVS and Epstein-Barr virus

1992 • 31 citations

Molecular structure and evolution of adrenergic and cholinergic receptors

1986 • 25 citations

Characterization of the major locus of immediate-early genes of rat cytomegalovirus

1993 • 25 citations

The right end of the unique region of the genome of human herpesvirus 6 U1102 contains a candidate immediate early gene enhancer and a homologue of the human cytomegalovirus US22 gene family

1992 • 19 citations

Infectivity determinants encoded in a conserved gene block of human herpesvirus-6

1992 • 14 citations

The molecular and cellular biology of human herpesvirus—6

1991 • 13 citations