Novel location and function of a thyroid hormone response element.

Basic local alignment search tool

1990 • 87,358 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Basic Local Alignment Search Tool

1990 • 12,947 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Messenger RNA degradation in eukaryotes

1993 • 858 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors

1991 • 603 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Retinoic acid and thyroid hormone induce gene expression through a common responsive element

1988 • 586 citations

Two nuclear signalling pathways for vitamin D

1993 • 559 citations

Autoradiography using storage phosphor technology

1990 • 531 citations

Steroid receptors and their associated proteins.

1993 • 513 citations

Modular structure of a chicken lysozyme silencer: Involvement of an unusual thyroid hormone receptor binding site

1990 • 487 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

Enhanced Transcription of c- myc in Bursal Lymphoma Cells Requires Continuous Protein Synthesis

1985 • 469 citations

Myc and Max associate in vivo.

1992 • 428 citations

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone

1987 • 347 citations

REGULATED mRNA STABILITY

1990 • 279 citations

Identification of a retinoic acid responsive enhancer 3′ of the murine homeobox gene Hox-1.6

1992 • 268 citations

Transcriptional Regulation of Hemoglobin Switching in Chicken Embryos

1981 • 265 citations

Gene Regulation by Steroid Hormones

1990 • 255 citations

Genetic complementation reveals a novel regulatory role for 3? untranslated regions in growth and differentiation

1993 • 245 citations

Isolation and characterization of rat cDNA clones for two distinct thyroid hormone receptors.

1988 • 237 citations

Steroid receptors and their associated proteins

1993 • 231 citations

Negative regulation of the thyroid-stimulating hormone alpha gene by thyroid hormone: receptor interaction adjacent to the TATA box.

1989 • 222 citations

An HMG-like protein that can switch a transcriptional activator to a repressor

1994 • 220 citations

Identification of Nuclear Factors that Enhance Binding of the Thyroid Hormone Receptor to a Thyroid Hormone Response Element

1989 • 219 citations

Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers.

1992 • 216 citations

A muscle-specific enhancer is located at the 3' end of the myosin light-chain 1/3 gene locus.

1988 • 212 citations

Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor

1990 • 211 citations

Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA.

1985 • 204 citations

Tumor suppression by RNA from the 3′ untranslated region of α-tropomyosin

1993 • 201 citations

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.

1990 • 197 citations

A 3′ enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene

1986 • 192 citations

A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements.

1990 • 192 citations

Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers.

1992 • 190 citations

Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected β type thyroid hormone receptor

1989 • 177 citations

Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein.

1993 • 163 citations

An everted repeat mediates retinoic acid induction of the gamma F-crystallin gene: evidence of a direct role for retinoids in lens development.

1993 • 157 citations

Mechanisms of transactivation by retinoic acid receptors

1993 • 156 citations

Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor.

1989 • 135 citations

Quantitation of endogenous thyroid hormone receptors alpha and beta during embryogenesis and metamorphosis in Xenopus laevis.

1994 • 135 citations

A major thyroid hormone response element in the third intron of the rat growth hormone gene.

1990 • 123 citations

A novel cis element mediating ligand-independent activation by c-ErbA: Implications for hormonal regulation

1993 • 119 citations

Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA

1992 • 102 citations

Binding characteristics of the thyroid hormone receptor homo- and heterodimers to consensus AGGTCA repeat motifs.

1992 • 94 citations

Thyroid hormone alters the DNA binding properties of chicken thyroid hormone receptors α and β

1992 • 87 citations

DNA sequences that act as high affinity targets for the vitamin D3 receptor in the absence of the retinoid X receptor.

1994 • 85 citations

An Estrogen-Inducible Protein Binds Specifically to a Sequence in the 3′ Untranslated Region of Estrogen-Stabilized Vitellogenin mRNA

1994 • 84 citations

High-level expression of the rat whey acidic protein gene is mediated by elements in the promoter and 3' untranslated region.

1992 • 78 citations

High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociation.

1993 • 71 citations

Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect.

1992 • 71 citations

c-erbA encodes multiple proteins in chicken erythroid cells.

1988 • 70 citations

Erythroid-specific transcription of the chicken histone H5 gene is directed by a 3′ enhancer

1987 • 70 citations

Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers

1992 • 68 citations

Thyroid hormone receptor transcriptional activity is potentially autoregulated by truncated forms of the receptor.

1992 • 63 citations

Thyroid hormone inhibits thyrotropin gene expression via a position-independent negative L-triiodothyronine-responsive element.

1992 • 59 citations

Nuclear Hormone Receptors Involved in Neoplasia: Erb A Exhibits a Novel DNA Sequence Specificity Determined by Amino Acids Outside of the Zinc-Finger Domain

1993 • 57 citations

An estrogen-inducible protein binds specifically to a sequence in the 3' untranslated region of estrogen-stabilized vitellogenin mRNA.

1994 • 52 citations

The thyroid hormone receptor gene (c-erbA alpha) is expressed in advance of thyroid gland maturation during the early embryonic development of Xenopus laevis.

1991 • 52 citations

Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene product.

1990 • 49 citations

Negative thyroid hormone control of human growth hormone gene expression is mediated by 3‘-untranslated/3‘-flanking DNA.

1992 • 38 citations

DNA sequences that act as high affinity targets for the vitamin D3 receptor in the absence of the retinoid X receptor

1994 • 30 citations

Binding characteristics of the thyroid hormone receptor homo- and heterodimers to consensus AGGTCA repeat motifs

1992 • 29 citations

High-Level Expression of the Rat Whey Acidic Protein Gene Is Mediated by Elements in the Promoter and 3' Untranslated Region

1992 • 24 citations

Isolation of a thyroid hormone-responsive gene by immunoprecipitation of thyroid hormone receptor-DNA complexes.

1994 • 23 citations

High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociation

1993 • 22 citations

Regulated mRna Stability

1990 • 18 citations

Thyroid Hormone Receptor Transcriptional Activity Is Potentially Autoregulated by Truncated Forms of the Receptor

1992 • 18 citations

Presence of Functional Cyclic AMP Responsive Element in the 3′-Untranslated Region of the Human Thrombomodulin Gene

1994 • 15 citations

c-erbA Encodes Multiple Proteins in Chicken Erythroid Cells

1988 • 13 citations

The Thyroid Hormone Receptor Gene (c-erbAα) Is Expressed in Advance of Thyroid Gland Maturation during the Early Embryonic Development of Xenopus laevis

1991 • 10 citations

Isolation of a Thyroid Hormone-Responsive Gene by Immunoprecipitation of Thyroid Hormone Receptor-DNA Complexes

1994 • 10 citations